Zobrazeno 1 - 10 of 30 pro vyhledávání: '"Xuefang Cheng"'
1
Akademický článek
UDP-glucuronosyltransferase 1A determinates intracellular accumulation and anti-cancer effect of β-lapachone in human colon cancer cells.
Autor: Huiying Liu, Qingran Li, Xuefang Cheng, Hong Wang, Guangji Wang, Haiping Hao
Publikováno v: PLoS ONE, Vol 10, Iss 2, p e0117051 (2015)
β-lapachone (β-lap), anNad(p)hquinone oxidoreductase 1 (NQO1) targeting antitumor drug candidate in phase II clinical trials, is metabolically eliminated via NQO1 mediated quinone reduction and subsequent UDP-glucuronosyltransferases (UGTs) catalyz
Externí odkaz: https://doaj.org/article/f98ae2b1c04a404fa62a8ca5a1d7403d
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2
Akademický článek
UDP-glucuronosyltransferase 1A compromises intracellular accumulation and anti-cancer effect of tanshinone IIA in human colon cancer cells.
Autor: Miao Liu, Qiong Wang, Fang Liu, Xuefang Cheng, Xiaolan Wu, Hong Wang, Mengqiu Wu, Ying Ma, Guangji Wang, Haiping Hao
Publikováno v: PLoS ONE, Vol 8, Iss 11, p e79172 (2013)
BACKGROUND AND PURPOSE: NAD(P)H: quinone oxidoreductase 1 (NQO1) mediated quinone reduction and subsequent UDP-glucuronosyltransferases (UGTs) catalyzed glucuronidation is the dominant metabolic pathway of tanshinone IIA (TSA), a promising anti-cance
Externí odkaz: https://doaj.org/article/a1016c44430747f88fd25f925f916b92
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3
Akademický článek
An NQO1-initiated and p53-independent apoptotic pathway determines the anti-tumor effect of tanshinone IIA against non-small cell lung cancer.
Autor: Fang Liu, Guo Yu, Guangji Wang, Huiying Liu, Xiaolan Wu, Qiong Wang, Miao Liu, Ke Liao, Mengqiu Wu, Xuefang Cheng, Haiping Hao
Publikováno v: PLoS ONE, Vol 7, Iss 7, p e42138 (2012)
NQO1 is an emerging and promising therapeutic target in cancer therapy. This study was to determine whether the anti-tumor effect of tanshinone IIA (TSA) is NQO1 dependent and to elucidate the underlying apoptotic cell death pathways. NQO1(+) A549 ce
Externí odkaz: https://doaj.org/article/38850368bbae45e6bb5d1eef2e0e3955
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4
Therapeutic drug monitoring of amikacin: quantification in plasma by liquid chromatography-tandem mass spectrometry and work experience of clinical pharmacists
Autor: Guorong Fan, Juan-Ni Hu, Lijie Xu, Guan-Hua Zhu, Xuefang Cheng, Qin Li
Publikováno v: European journal of hospital pharmacy : science and practice. 29(e1)
Objectives As part of the service provided by clinical pharmacists in our hospital, an assay for plasma amikacin quantification by liquid chromatography-tandem mass spectrometry (LC-MS/MS) has been established for clinical use since 2018. This study
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50b255f39f44c4788cb5d9debd6bdd1b
https://pubmed.ncbi.nlm.nih.gov/34789474
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7
NAMPT inhibition synergizes with NQO1-targeting agents in inducing apoptotic cell death in non-small cell lung cancer cells
Autor: Huiying Liu, Haiping Hao, Guangji Wang, Qing-Ran Li, Xuefang Cheng
Publikováno v: Chinese Journal of Natural Medicines. 14:582-589
Nicotinamide phosphoribosyltransferase (NAMPT) catalyzes the first rate-limiting step in converting nicotinamide to NAD(+), essential for a number of enzymes and regulatory proteins involved in a variety of cellular processes, including deacetylation
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::adfadd7e11b68914ae6ee89c54e93531
https://doi.org/10.1016/s1875-5364(16)30068-1
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8
The complete mitochondrial genomes of four cockroaches (Insecta: Blattodea) and phylogenetic analyses within cockroaches
Autor: Jia-Yong Zhang, Le-Ping Zhang, Xuefang Cheng, Kenneth B. Storey, Dan-Na Yu
Publikováno v: Gene. 586:115-122
Three complete mitochondrial genomes of Blaberidae (Insecta: Blattodea) (Gromphadorhina portentosa, Panchlora nivea, Blaptica dubia) and one complete mt genome of Blattidae (Insecta: Blattodea) (Shelfordella lateralis) were sequenced to further under
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b18ed521456904955d03239e1ce8ffb
https://doi.org/10.1016/j.gene.2016.03.057
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9
Heat transfer of water flowing upward in vertical annuli with spacers at high pressure conditions
Autor: Hengle Gu, Meng Zhao, Hongbo Li, Xuefang Cheng
Publikováno v: Annals of Nuclear Energy. 87:209-216
Experimental studies on heat transfer to water flowing upward in a concentric annular channel are carried out at the SWAMUP test facility at both subcritical and supercritical pressure conditions. The vertical annuli contain a heated inner tube of 8
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4a54d9bc81f933dfce8682d8028dbfad
https://doi.org/10.1016/j.anucene.2015.08.011
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10
Pharmacodynamics and potential synergistic effects of Mai-Luo-Ning injection on cardiovascular protection, based on molecular docking
Autor: Hanyuan Shen, Xiao-Yi Yu, Hong Wang, Xuefang Cheng, Yu-Zheng Wu, Haiping Hao, Liang Wu, Guangji Wang
Publikováno v: Chinese Journal of Natural Medicines. 13:815-822
As a computer-assisted approach, molecular docking has been universally applied in drug research and development and plays an important role in the investigation and evaluation of herbal medicines. Herein, the method was used to estimate the pharmaco
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5eccf97bf7c8e5e50c3de2c0f521952f
https://doi.org/10.1016/s1875-5364(15)30085-6
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