Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Xuefang Cheng"'
Publikováno v:
PLoS ONE, Vol 10, Iss 2, p e0117051 (2015)
β-lapachone (β-lap), anNad(p)hquinone oxidoreductase 1 (NQO1) targeting antitumor drug candidate in phase II clinical trials, is metabolically eliminated via NQO1 mediated quinone reduction and subsequent UDP-glucuronosyltransferases (UGTs) catalyz
Externí odkaz:
https://doaj.org/article/f98ae2b1c04a404fa62a8ca5a1d7403d
Publikováno v:
European journal of hospital pharmacy : science and practice. 29(e1)
Objectives As part of the service provided by clinical pharmacists in our hospital, an assay for plasma amikacin quantification by liquid chromatography-tandem mass spectrometry (LC-MS/MS) has been established for clinical use since 2018. This study
Autor:
Miao Liu, Qiong Wang, Fang Liu, Xuefang Cheng, Xiaolan Wu, Hong Wang, Mengqiu Wu, Ying Ma, Guangji Wang, Haiping Hao
Publikováno v:
PLoS ONE, Vol 8, Iss 11, p e79172 (2013)
BACKGROUND AND PURPOSE: NAD(P)H: quinone oxidoreductase 1 (NQO1) mediated quinone reduction and subsequent UDP-glucuronosyltransferases (UGTs) catalyzed glucuronidation is the dominant metabolic pathway of tanshinone IIA (TSA), a promising anti-cance
Externí odkaz:
https://doaj.org/article/a1016c44430747f88fd25f925f916b92
Autor:
Fang Liu, Guo Yu, Guangji Wang, Huiying Liu, Xiaolan Wu, Qiong Wang, Miao Liu, Ke Liao, Mengqiu Wu, Xuefang Cheng, Haiping Hao
Publikováno v:
PLoS ONE, Vol 7, Iss 7, p e42138 (2012)
NQO1 is an emerging and promising therapeutic target in cancer therapy. This study was to determine whether the anti-tumor effect of tanshinone IIA (TSA) is NQO1 dependent and to elucidate the underlying apoptotic cell death pathways. NQO1(+) A549 ce
Externí odkaz:
https://doaj.org/article/38850368bbae45e6bb5d1eef2e0e3955
Publikováno v:
Pharmaceutical Care and Research. 17:173-229
Publikováno v:
European Journal of Hospital Pharmacy; 2022 Special Issue, Vol. 29, pe77-e82, 6p
Publikováno v:
Chinese Journal of Natural Medicines. 14:582-589
Nicotinamide phosphoribosyltransferase (NAMPT) catalyzes the first rate-limiting step in converting nicotinamide to NAD(+), essential for a number of enzymes and regulatory proteins involved in a variety of cellular processes, including deacetylation
Publikováno v:
Gene. 586:115-122
Three complete mitochondrial genomes of Blaberidae (Insecta: Blattodea) (Gromphadorhina portentosa, Panchlora nivea, Blaptica dubia) and one complete mt genome of Blattidae (Insecta: Blattodea) (Shelfordella lateralis) were sequenced to further under
Publikováno v:
Annals of Nuclear Energy. 87:209-216
Experimental studies on heat transfer to water flowing upward in a concentric annular channel are carried out at the SWAMUP test facility at both subcritical and supercritical pressure conditions. The vertical annuli contain a heated inner tube of 8
Autor:
Hanyuan Shen, Xiao-Yi Yu, Hong Wang, Xuefang Cheng, Yu-Zheng Wu, Haiping Hao, Liang Wu, Guangji Wang
Publikováno v:
Chinese Journal of Natural Medicines. 13:815-822
As a computer-assisted approach, molecular docking has been universally applied in drug research and development and plays an important role in the investigation and evaluation of herbal medicines. Herein, the method was used to estimate the pharmaco