Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Xueer Qiu"'
Autor:
Teressa M. Shaw, Devra Huey, Makky Mousa-Makky, Jared Compaleo, Kylie Nennig, Aadit P. Shah, Fei Jiang, Xueer Qiu, Devon Klipsic, Raymond R. R. Rowland, Igor I. Slukvin, Meagan E. Sullender, Megan T. Baldridge, Haichang Li, Cody J. Warren, Adam L. Bailey
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Arteriviruses infect a variety of mammalian hosts, but the receptors used by these viruses to enter cells are poorly understood. We identified the neonatal Fc receptor (FcRn) as an important pro-viral host factor via comparative genome-wide
Externí odkaz:
https://doaj.org/article/6e7bb8aedb52446288ced11b8dff371e
Autor:
Han-Yuan Liu, Zhengnian Li, Theresia Reindl, Zhixiang He, Xueer Qiu, Ryan P. Golden, Katherine A. Donovan, Adam Bailey, Eric S. Fischer, Tinghu Zhang, Nathanael S. Gray, Priscilla L. Yang
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Viral genetic diversity presents significant challenges in developing antivirals with broad-spectrum activity and high barriers to resistance. Here we report development of proteolysis targeting chimeras (PROTACs) targeting the dengue virus
Externí odkaz:
https://doaj.org/article/7d9b7ee5a0a0432baec898202007a68e
Autor:
Teressa M. Shaw, Wei Zhang, Sara S. McCoy, Adam Pagenkopf, Diana M. Carp, Shivani Garg, Maxwell H. Parker, Xueer Qiu, Robert H. Scofield, Jacques Galipeau, Yun Liang
Publikováno v:
Journal of Molecular Medicine. 100:1253-1265
Autor:
Ruud H. Wijdeven, Birol Cabukusta, Felix M. Behr, Xueer Qiu, Deeba Amiri, Daniel M. Borras, Ramon Arens, Yun Liang, Jacques Neefjes
Publikováno v:
J Immunol
The Journal of Immunology, 209(5), 907-915. AMER ASSOC IMMUNOLOGISTS
The Journal of Immunology, 209(5), 907-915. AMER ASSOC IMMUNOLOGISTS
The PD-L1/2–PD-1 immune checkpoint is essential for the proper induction of peripheral tolerance and limits autoimmunity, whereas tumor cells exploit their expression to promote immune evasion. Many different cell types express PD-L1/2, either cons
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e97fd95a95a81e591d8b8d3410576b0e
https://hdl.handle.net/1887/3486763
https://hdl.handle.net/1887/3486763
Autor:
Majed Alabdulhafid, Zobaida Alsum, Fahad A. Bashiri, Abdullah A. Alangari, Jacinta Bustamante, Emmanuelle Jouanguy, Rabih Halwani, Malak Alghamdi, Hamdy H. Hassan, Dusan Bogunovic, Areej Rashid Alkahtani, Fahad Alsohime, Najla Alotaibi, Nouf Alkhamis, Mohamad-Hani Temsah, Marta Martín-Fernández, Conor Gruber, Ayman Al-Eyadhy, Saleh Al-Muhsen, Xueer Qiu, Gamal M Hasan, Tom Le Voyer, Sofija Buta, Jean-Laurent Casanova
Publikováno v:
N Engl J Med
Deficiency of ubiquitin-specific peptidase 18 (USP18) is a severe type I interferonopathy. USP18 down-regulates type I interferon signaling by blocking the access of Janus-associated kinase 1 (JAK1) to the type I interferon receptor. The absence of U
The PD-L1/2 – PD-1 immune checkpoint is essential for the proper induction of peripheral tolerance and limits autoimmunity, whereas tumor cells exploit their expression to promote immune evasion. Many different cell types express PD-L1/2, either co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e68d0429a2aeaef3cba9b1160fd90f26
https://doi.org/10.1101/2021.08.18.456771
https://doi.org/10.1101/2021.08.18.456771
Autor:
Jérémie Rosain, Sofija Buta, Jennie B. Altman, Dusan Bogunovic, Aziz Bousfiha, Fatima Ailal, Marta Martín-Fernández, Justin Taft, Xueer Qiu, Jacinta Bustamante, Conor Gruber, Jean-Laurent Casanova
Type I interferonopathies are monogenic disorders characterized by enhanced Type I interferon (IFN-I) activity. Inherited ISG15 and USP18 deficiencies underlie type I interferonopathies by preventing the regulation of late responses to IFN-I. Specifi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4db6e1b5e7f698ab05c9110a44b4543
Autor:
Jean-Laurent Casanova, Justin Taft, Xueer Qiu, Jennie B. Altman, Dusan Bogunovic, Aziz Bousfiha, Marta Martín-Fernández, Fatima Ailal, Conor Gruber, Sofija Buta, Jérémie Rosain, Jacinta Bustamante
Publikováno v:
The Journal of Experimental Medicine
Gruber et al. describe a gain-of-function mutation in STAT2 that leads to a lethal autoinflammatory disease with autosomal recessive inheritance. This syndrome defines a novel form of type I interferonopathy characterized by impaired regulation of th
Publikováno v:
Sensors and Actuators B: Chemical. 345:130417
High Lactate Dehydrogenase (LDH) activity, a distinct feature of cancer cells, is a possible causative factor for cancer cells to metastasize, infiltrate, invade, and deteriorate. The exploration of upconversion hybrid nano fluorescent sensor (HNFS)
Autor:
Teressa Shaw, Wei Zhang, Sara S. McCoy, Xueer Qiu, Adam Pagenkopf, Jacques Galipeau, Yun Liang
Publikováno v:
The Journal of Immunology. 206:105.01-105.01
Many autoimmune diseases feature strikingly increased prevalence in females, such as systemic lupus erythematosus (female-to-male ratio 9:1), systemic sclerosis (female-to-male ratio 11:1) and Sjögren’s syndrome (female-to-male ratio 14:1). Howeve