Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Xuechi Lin"'
Publikováno v:
International Journal of Molecular Medicine. 40:235-242
Purvalanol A is a highly selective inhibitor of Cdc2 [also known as cyclin-dependent kinase 1 (CDK1)]. Taxol is an anti-tumor chemotherapeutic drug which is widely used clinically. In this study, the CDK1 inhibitor, purvalanol A was applied to explor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::056fe389ae48f70171d5e9e8c35a580f
https://doi.org/10.3892/ijmm.2017.2989
https://doi.org/10.3892/ijmm.2017.2989
Publikováno v:
Oncology reports. 41(3)
Our previous studies demonstrated that high expression of oncoprotein 18 (Op18)/stathmin promotes malignant transformation of non‑small cell lung cancer NCI‑H1299 cells. Investigation of the cellular settings determined that NCI‑H1299 cells wer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e08d8b443b5b7a8320ddd26d83d1536c
https://pubmed.ncbi.nlm.nih.gov/30628717
https://pubmed.ncbi.nlm.nih.gov/30628717
Publikováno v:
Oncology reports. 41(1)
Our previous studies have identified that silencing oncoprotein 18 (Op18)/stathmin via RNA interference (RNAi) inhibited autocrine interleukin‑10 (IL‑10) and enhanced the sensitivity to Taxol in NCI‑H1299 non‑small cell lung cancer cells. In
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5932e867ecc3012e003f84c37f48dffa
https://pubmed.ncbi.nlm.nih.gov/30320402
https://pubmed.ncbi.nlm.nih.gov/30320402
Publikováno v:
Cell biology and toxicology. 34(1)
Stathmin (STMN) plays a vital role in maintaining the malignant behavior of cancer through directly regulating microtubule dynamics equilibrium. Taxol, an effective chemotherapeutics mainly acting to promote microtubule polymerization, has been comme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a17c92f01736224e941d9ed2e268ff63
https://pubmed.ncbi.nlm.nih.gov/28589243
https://pubmed.ncbi.nlm.nih.gov/28589243
Publikováno v:
Oncology reports. 37(4)
Taxol (paclitaxel) and vinblastine (VBL) are both efficacious chemotherapeutic agents that target the microtubules of tumor cells, but each functions in a mutual antagonistic manner. Op18/stathmin is a small molecular phosphoprotein which promotes de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8902f9c93b5c3f39212a8b9150ec0bd8
https://pubmed.ncbi.nlm.nih.gov/28259950
https://pubmed.ncbi.nlm.nih.gov/28259950
Publikováno v:
Cancer biotherapyradiopharmaceuticals. 31(2)
Taxol is a cytotoxic antiepithelioma chemotherapy drug widely used clinically, which results in appearing a broad range of taxol-resistant tumors. Oncoprotein 18 (Op18)/stathmin is a genetically highly conserved small-molecule cytosolic phosphoprotei
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e9b551e132a42d37afde3ec3ae830d3
https://pubmed.ncbi.nlm.nih.gov/26881937
https://pubmed.ncbi.nlm.nih.gov/26881937
Op18/stathmin is involved in the resistance of taxol among different epithelial carcinoma cell lines
Publikováno v:
Cancer biotherapyradiopharmaceuticals. 29(9)
Taxol is an effective chemotherapeutic agent against epithelial-derived carcinomas, and resistance of carcinoma cells to taxol has developed with the wide prescription of the drug. In this study, five different epithelial carcinoma cell lines were ra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d05b396c301776ef62417f0b5b27a751
https://pubmed.ncbi.nlm.nih.gov/25379611
https://pubmed.ncbi.nlm.nih.gov/25379611
Autor:
Min Tang, Lili Li, Zijian Li, Xuechi Lin, Juan Xu, Xiaoqian Ma, Ya Cao, Sufang Liu, Lili Guo, Yongguang Tao
Publikováno v:
Cancer Sci
The MAPKs are activated by a variety of cellular stimuli to participate in a series of signaling cascades and mediate diverse intracellular responses. One potential target of the MAPKs is Op18/stathmin, a molecule that acts as an integrator of divers
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb45413d5ef18db12c7dbb25c88109f3
https://pubmed.ncbi.nlm.nih.gov/22417000
https://pubmed.ncbi.nlm.nih.gov/22417000
Autor:
Xiaoqian Ma, Lili Li, Yongguang Tao, Zijian Li, Lili Guo, Xuechi Lin, Xiangjian Luo, Sufang Liu, Ya Cao
Publikováno v:
International journal of cancer. 124(5)
Oncoprotein 18/stathmin (Op18/stathmin) plays a crucial role in maintaining cell biological characteristics by regulating microtubule dynamics, especially entry into mitosis; phosphorylated Op18/stathmin promotes microtubule polymerization to form th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bc423678868f83ef35715aac5d478f0
https://pubmed.ncbi.nlm.nih.gov/19048596
https://pubmed.ncbi.nlm.nih.gov/19048596
Autor:
Yanfei Gong, Xuechi Lin, Liting Cai, Zuping Zhang, Wei Liu, Shun-ke Zhang, Qingren Zeng, Benwen Li, Tiebing Zeng
Publikováno v:
The Journal of parasitology. 94(2)
We previously reported that immunization with intact live cells from schistosomula of Schistosoma japonicum (S.j) partially protected the Kunming strain of mice from challenge infection. In the present work, 2 immune protective experiments were desig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53a67471d6801ed069818eb0e4485e14
https://pubmed.ncbi.nlm.nih.gov/18564740
https://pubmed.ncbi.nlm.nih.gov/18564740