Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Xuechai Chen"'
Autor:
Jianan Wang, Yuanyuan Ran, Zihan Li, Tianyuan Zhao, Fangfang Zhang, Juan Wang, Zongjian Liu, Xuechai Chen
Publikováno v:
Neural Regeneration Research, Vol 20, Iss 3, Pp 887-899 (2025)
Salsolinol (1-methyl-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline, Sal) is a catechol isoquinoline that causes neurotoxicity and shares structural similarity with 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine, an environmental toxin that causes Parkin
Externí odkaz:
https://doaj.org/article/3fc9e4e0783749c79e7d74ef72642f50
Autor:
Zihan Li, Jiarui Wu, Tianyuan Zhao, Yiyun Wei, Yajing Xu, Zongjian Liu, Xiaoqiong Li, Xuechai Chen
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 18 (2024)
Due to the increased crewed spaceflights in recent years, it is vital to understand how the space environment affects human health. A lack of gravitational force is known to risk multiple physiological functions of astronauts, particularly damage to
Externí odkaz:
https://doaj.org/article/c1a387bdafa246f88b330add1603ec45
Autor:
Xuechai Chen, Jianan Wang, Muhammad Tahir, Fangfang Zhang, Yuanyuan Ran, Zongjian Liu, Juan Wang
Publikováno v:
Cell & Bioscience, Vol 11, Iss 1, Pp 1-15 (2021)
Abstract Autophagy is a conserved degradation process crucial to maintaining the primary function of cellular and organismal metabolism. Impaired autophagy could develop numerous diseases, including cancer, cardiomyopathy, neurodegenerative disorders
Externí odkaz:
https://doaj.org/article/82da4cb1935048eb85db49851c2fe4f2
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 16 (2022)
N6-methyladenosine (m6A) is the most abundant post-transcription modification, widely occurring in eukaryotic mRNA and non-coding RNA. m6A modification is highly enriched in the mammalian brain and is associated with neurological diseases like Alzhei
Externí odkaz:
https://doaj.org/article/a187e3b6d74141a4b1f00fa8bdfb3846
Autor:
Qianqian Xiong, Xiaotong Zheng, Jianan Wang, Zixuan Chen, Yulin Deng, Rugang Zhong, Juan Wang, Xuechai Chen
Publikováno v:
Journal of Integrative Neuroscience, Vol 21, Iss 2, p 071 (2022)
As a catechol isoquinoline, salsolinol (Sal) is widely distributed in mammalian brains, and is increased in the cerebrospinal fluid (CSF) and urine of Parkinsonian patients. Sal can be metabolized to N-methyl-salsolinol (NM-Sal), an MPP+-like neuroto
Externí odkaz:
https://doaj.org/article/b95a3b1ad93a43bdab784e2a0eaaee7f
Autor:
Yuting Li, Xuechai Chen, Qianqian Xiong, Yong Chen, Hongyu Zhao, Muhammad Tahir, Jingdong Song, Bing Zhou, Juan Wang
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
Autophagy starts with the initiation and nucleation of isolation membranes, which further expand and seal to form autophagosomes. The regulation of isolation membrane closure remains poorly understood. CK1δ is a member of the casein kinase I family
Externí odkaz:
https://doaj.org/article/435624c7411144bda547722a10c463df
Publikováno v:
Cells, Vol 10, Iss 11, p 2814 (2021)
Autophagy is an evolutionarily conserved pathway, in which cytoplasmic components are sequestered within double-membrane vesicles called autophagosomes and then transported into lysosomes or vacuoles for degradation. Over 40 conserved autophagy-relat
Externí odkaz:
https://doaj.org/article/1db081a9974f4187835db54a744cb06e
Publikováno v:
Current Stem Cell Research & Therapy. 17:13-25
Emerging evidence suggests that ascorbic acid (vitamin C) enhances the reprogramming process by multiple mechanisms primarily due to its cofactor role in Fe(II) and 2-oxoglutarate-dependent dioxygenases, including the DNA demethylases Ten Eleven Tran
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::152315ddc63f401f649488f6cdc8d9d7
https://doi.org/10.2174/1574888x16666210714152730
https://doi.org/10.2174/1574888x16666210714152730
Autor:
Jianan Wang, Yuanyuan Ran, Zihan Li, Tianyuan Zhao, Fangfang Zhang, Juan Wang, Zongjian Liu, Xuechai Chen
Publikováno v:
Neural Regeneration Research; Mar2025, Vol. 20 Issue 3, p887-899, 13p
Autor:
Fuhai Gao, Jianing Xi, Xuechai Chen, Zongjian Liu, Shuiqing Yang, Lin Ye, Wei Su, Guiqin Tian, Yuanyuan Ran, Zitong Ding
Publikováno v:
Oxidative Medicine and Cellular Longevity
Oxidative Medicine and Cellular Longevity, Vol 2021 (2021)
Oxidative Medicine and Cellular Longevity, Vol 2021 (2021)
NLRP3 inflammasome-mediated pyroptosis is a proinflammatory programmed cell death pathway, which plays a vital role in functional outcomes after stroke. We previously described the beneficial effects of curcumin against stroke-induced neuronal damage
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::151777792ae97f83f80175185d648a0e
https://doi.org/10.1155/2021/1552127
https://doi.org/10.1155/2021/1552127