Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Xuebiao Wu"'
Autor:
Ruocen Liao, Xingyu Chen, Qianhua Cao, Yifan Wang, Zhaorui Miao, Xingyu Lei, Qianjin Jiang, Jie Chen, Xuebiao Wu, Xiaoli Li, Jun Li, Chenfang Dong
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
BackgroundBasal-like breast cancer (BLBC) is associated with a poor clinical outcome; however, the mechanism of BLBC aggressiveness is still unclear. It has been shown that a linker histone functions as either a positive or negative regulator of gene
Externí odkaz:
https://doaj.org/article/ce07a28d323c46f784358cf5b4cda524
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
BackgroundE-cadherin, a hallmark of epithelial-mesenchymal transition (EMT), is often repressed due to Snail-mediated epigenetic modification; however, the exact mechanism remains unclear. There is an urgent need to understand the determinants of tum
Externí odkaz:
https://doaj.org/article/11dc1ae6fe3d4e68b282a095a7b69f3e
Autor:
Qian Zhao, Lu Qian, Yuefan Guo, Jinhui Lü, Danni Li, Heying Xie, Qiong Wang, Wenjing Ma, Pengfei Liu, Yu Liu, Tao Wang, Xuebiao Wu, Junyi Han, Zuoren Yu
Publikováno v:
Theranostics. 13:2337-2349
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::153614c950f26709fc489667524f97cd
https://doi.org/10.7150/thno.82538
https://doi.org/10.7150/thno.82538
Publikováno v:
The Pharmacogenomics Journal
Although numerous genetic studies have reported the link between Val66Met in BDNF gene with smoking, the findings remain controversial, mainly due to small-to-moderate sample sizes. The main aim of current investigation is to explore whether the vari
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e7296b08f8fdc3a8e0d7e575757a0c9
http://europepmc.org/articles/PMC7253357
http://europepmc.org/articles/PMC7253357
Publikováno v:
Theranostics. 9:34-47
Basal-like breast cancer (BLBC) is the most aggressive subtype with a poor clinical outcome; however, the molecular mechanisms underlying aggressiveness in BLBC remain poorly understood. Methods: The effects of gamma-aminobutyrate aminotransferase (A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f367200bdea13260387cbd8e4445b122
https://doi.org/10.7150/thno.29407
https://doi.org/10.7150/thno.29407
Autor:
Huixin Liu, Xingyu Chen, Guoping Ren, Qianhua Cao, Jun Li, Chenfang Dong, Ruocen Liao, Xuebiao Wu
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-10 (2018)
Scientific Reports
Scientific Reports
Basal-like breast cancer (BLBC) is associated with a poor clinical outcome due to the few treatment options and absence of effective targeted agents. Here, we show that malic enzyme 1 (ME1) is dramatically upregulated in BLBC due to ME1 copy number a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7dbbc4784afab3b0b5c7effbe6f5fb8
http://link.springer.com/article/10.1038/s41598-018-35106-y
http://link.springer.com/article/10.1038/s41598-018-35106-y
Publikováno v:
Journal of Resources & Ecology; 2022, Vol. 13 Issue 3, p407-416, 10p
Autor:
Xingyu Chen, Qianhua Cao, Chenfang Dong, Guoping Ren, Xuebiao Wu, Yanjia Tan, Jian Huang, Ruocen Liao, Li Wang, Panpan Huang
Publikováno v:
The Journal of Experimental Medicine
Cao et al. show that UGT8 promotes BLBC progression through activating sulfatide–αVβ5 axis. ZA is identified as a direct inhibitor of UGT8 and suppresses BLBC progression, suggesting that inhibition of UGT8 offers a promising opportunity for trea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88ab22a0bc0f540737529fc69e109ea4
http://europepmc.org/articles/PMC5987921
http://europepmc.org/articles/PMC5987921
Autor:
Xuebiao Wu, Chenfang Dong, Xiaoli Li, Panpan Huang, Yifan Wang, Xingyu Chen, Ruocen Liao, Qianhua Cao
Publikováno v:
Theranostics
Rationale: Basal-like breast cancer (BLBC) is associated with high grade, distant metastasis, and poor prognosis; however, the mechanism underlying aggressiveness of BLBC is still unclear. Emerging evidence has suggested that phospholipid scramblase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa2604903db55212a28a0d27f9637ee4
https://pubmed.ncbi.nlm.nih.gov/32292520
https://pubmed.ncbi.nlm.nih.gov/32292520
Autor:
Jingpei Long, Qiang Fu, Qianhua Cao, Chenfang Dong, Ruocen Liao, Huixin Liu, Xiaoli Li, Mengjie Wang, Jun Yao, Danping Wang, Xingyu Chen, Xuebiao Wu, Jie Yu
Publikováno v:
The Journal of Experimental Medicine
The treatment of BLBC represents an unmet medical need. Wu et al. show that AKR1B1 facilitates BLBC progression through a positive feedback loop that activates the EMT program, suggesting that inhibition of AKR1B1 has the potential to become a valuab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b2c64dbfc1c7e21d6a8a10f4b68a2a7
http://europepmc.org/articles/PMC5379972
http://europepmc.org/articles/PMC5379972