Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Xue-mei Hao"'
Autor:
Xiao-Chen Li, Ling Wei, Guang-Qin Zhang, Zai-Ling Bai, Ying-Ying Hu, Peng Zhou, Shu-Hua Bai, Zhen Chai, Edward G Lakatta, Xue-Mei Hao, Shi-Qiang Wang
Publikováno v:
PLoS ONE, Vol 6, Iss 9, p e24787 (2011)
Heart tissues from hibernating mammals, such as ground squirrels, are able to endure hypothermia, hypoxia and other extreme insulting factors that are fatal for human and nonhibernating mammals. This study was designed to understand adaptive mechanis
Externí odkaz:
https://doaj.org/article/29418ab060584caeab96d627491b52d0
Autor:
Ming Xu, Peng Zhou, Shi-Ming Xu, Yin Liu, Xinheng Feng, Shu-Hua Bai, Yan Bai, Xue-Mei Hao, Qide Han, Youyi Zhang, Shi-Qiang Wang
Publikováno v:
PLoS Biology, Vol 5, Iss 2, p e21 (2007)
Pressure overload-induced hypertrophy is a key step leading to heart failure. The Ca(2+)-induced Ca(2+) release (CICR) process that governs cardiac contractility is defective in hypertrophy/heart failure, but the molecular mechanisms remain elusive.
Externí odkaz:
https://doaj.org/article/35ca7cafa33e4b63946bec55f5d574df
Publikováno v:
Brain research bulletin. 165
The translocator protein (TSPO), once known as peripheral-type benzodiazepine receptor, was reported to be related with several physiological functions. Etifoxine is a clinically available anxiolytic drug, and has recently shown neuroprotective effec
Autor:
Shi-Qiang Wang, Yun Bo Guo, Shu Hua Bai, Xue Mei Hao, Peng Zhou, Yan-Ting Zhao, Edward G. Lakatta, Shi Ming Xu, Heping Cheng
Publikováno v:
Proceedings of the National Academy of Sciences. 106:18028-18033
As the most prototypical G protein-coupled receptor, β-adrenergic receptor (βAR) regulates the pace and strength of heart beating by enhancing and synchronizing L-type channel (LCC) Ca 2+ influx, which in turn elicits greater sarcoplasmic reticulum
Publikováno v:
Drug Development Research. 58:111-115
Whole-cell patch-clamp recording techniques were applied to measure I Na in isolated ventricular myocytes of guinea pigs and CA1 neurons of hippocampus of Sprague-Dawley rats treated with L-thyroxine (0.5 mg/kg i.p. for 8-10 days). We found that the
Publikováno v:
Canadian Journal of Physiology and Pharmacology. 79:621-626
To elucidate possible ionic mechanisms of antimyocardial ischemia and antiarrythmia of tetramethyl pyrazine (TP), we studied L-type Ca2+ currents (ICa.L) in adult rat ventricular myocytes using the whole-cell patch-clamp technique. The results showed
Publikováno v:
Chinese Medical Journal. 120:2039-2041
Autor:
Hai-Tao Li, Sixun Peng, De-Zai Dai, Bei-Ai Zhou, Xue-Mei Hao, Wen-long Huang, Yi-qun Tang, Lu-Fan An, Feng Yu, Chai-Hong Hu
Publikováno v:
Drug Development Research. 39:138-146
CPU 86017 is derived from tetrahydroberberine and possesses potent anti-arrhythmic activities in animal models. Its effects on ion channels were studied by electrophysiological approaches. The action potential duration (APD) of isolated myocytes of g
Autor:
Edward G. Lakatta, Guangqin Zhang, Zhen Chai, Xue Mei Hao, Xiao Chen Li, Ling Wei, Shi-Qiang Wang, Zai Ling Bai, Peng Zhou, Shu Hua Bai, Ying Ying Hu
Publikováno v:
PLoS ONE
PLoS ONE, Vol 6, Iss 9, p e24787 (2011)
PLoS ONE, Vol 6, Iss 9, p e24787 (2011)
Heart tissues from hibernating mammals, such as ground squirrels, are able to endure hypothermia, hypoxia and other extreme insulting factors that are fatal for human and nonhibernating mammals. This study was designed to understand adaptive mechanis
Publikováno v:
Zhonghua yi xue za zhi. 87(10)
To express the human HCN2 and HCN4 genes in HEK293 cells and investigate the electrophysiology of the expressed channel protein.cDNA encoding human HCN2 or HCN4 gene was ligated into a shuttle vector pAdTrack-CMV. Homologous recombination was perform