Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Xue-lan Wang"'
Publikováno v:
Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology. 31(6)
Alzheimer's Disease (AD) is a chronic neurodegenerative disease that usually takes many years from preclinical phase to prodromal phase characterized by mild symptoms before the onset of dementia. Once diagnosed with AD, the brain is already severely
Autor:
Ig-wei, Gao, Li-xia, Yu, Yan, Hong, Chao, Niu, Yuan, Chen, Xue-lan, Wang, Ru-zhu, Chen, Wang Hai
Publikováno v:
Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology. 31(5)
To study the mechanism of learning and memory dysfuction in the transgenic mouse expressing human tau 40 isoform with P301L mutation (F10).The human tau protein expression and phosphor-tau protein levels were detected with Western blot method. The ne
Publikováno v:
Neurochemical research. 41(4)
Different patterns of olfactory dysfunction have been found in both patients and mouse models of Alzheimer's Disease. However, the underlying mechanism of the dysfunction remained unknown. Deficits of nitric oxide production in brain can cause olfact
Autor:
Yuan, Chen, Li-Xia, Yu, Yan, Hong, Chao, Niu, Jing-Wei, Gao, Hong, Jin, Xue-Lan, Wang, Hai, Wang
Publikováno v:
Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology. 30(3)
To investigate the effect of hypobaric hypoxia (HH)on the cognitive function of mice and the phosphorylation of tau protein in mice brain.Forty male mice were randomly divided into 4 groups (n = 10): static control (control) group, 8 hours (8 h) grou
Publikováno v:
Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology. 28(4)
To establish the triple-transgenic mouse model and study their biological characteristics by molecular biology, behavior and pathology.Hybrid the Tau and amyloid precursor protein (APP)/presenilins (PS1) transgenic mouse, the genotype of offspring mi
Autor:
Yan-yan, Wang, Ru-zhui, Chen, Xiao-nani, Zhu, Jing, Liu, Zhi-hui, Li, Xiu-juan, Liu, Xin, Na, Shan-shan, Liang, Guo-guang, Qiu, Wei, Zhang, Hai, Wang, Xue-lan, Wang
Publikováno v:
Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology. 28(3)
To establish homozygous transgenic mouse strain expressing human tau isoform with P301L mutation.Five transgenic mice expressing human tau isoform with P301L mutation were obtained by microinjection into male nuclei. Homozygote and hemizygote were id
Publikováno v:
Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials. 31(4)
Suavissimoside R1 was isolated and identified as an active ingredient from Roots of Rubus parvifollus L, which exhibited protective effect on dopaminergic neurons against MPP+ toxicity.The protective effects of crude extracts were investigated after
Autor:
Jian-Ping, Yu, Jin, He, Dan, Liu, Chun-Yu, Deng, Xiao-Nan, Zhu, Xue-Lan, Wang, Yong, Wang, Ru-Zhu, Chen
Publikováno v:
Sheng li xue bao : [Acta physiologica Sinica]. 59(6)
Nicotine enhances the function of learning and memory, but the underlying mechanism still remains unclear. Hippocampal long-term potentiation (LTP) is assumed to be a cellular mechanism of learning and memory. Our previous experiments showed that wit