Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Xue-Zheng Dai"'
Autor:
Robert J. Bache, Xue-Zheng Dai
Publikováno v:
Cardiovascular Research. 26:351-356
Objective: The aim was to test the hypothesis that thromboxane A2 can cause vasoconstriction of coronary resistance vessels during exercise in hypoperfused regions of myocardium distal to an arterial stenosis. Methods: Eight adult mongrel dogs were s
Publikováno v:
Journal of the American College of Cardiology. 19:687-693
This study was performed to determine whether thromboxane A2 (as the analogue U46619) and serotonin can cause vasoconstriction of moderately well developed coronary collateral vessels. Studies were carried out in seven adult mongrel dogs 2 to 4 month
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 261:H280-H286
The effect of alpha 1-adrenergic blockade with prazosin on myocardial blood flow at rest and during two levels of treadmill exercise was assessed in 16 chronically instrumented dogs 9-14 days after myocardial infarction had been produced by occlusion
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 260:H1489-H1494
This study was carried out to test the hypothesis that alpha-adrenergic vasoconstriction limits coronary blood flow (CBF) during exercise in the chronically pressure overloaded, hypertrophied left ventricle. Studies were performed in dogs in which le
Publikováno v:
Journal of Cardiovascular Pharmacology. 16:890-895
This study examined the effect of pinacidil on the transmural distribution of myocardial blood flow in the chronically pressure overloaded hypertrophied left ventricle. Studies were performed in six dogs in which banding of the ascending aorta had re
Publikováno v:
Circulation. 81:1967-1973
This study was performed to determine if a coronary artery stenosis would result in more-severe perfusion abnormalities in hypertrophied compared with normal canine hearts during exercise. Studies were performed in eight normal control dogs and in se
Autor:
Robert J. Bache, Xue Zheng Dai
Publikováno v:
Journal of the American College of Cardiology. 15(5):1157-1164
The hypothesis that abnormally increased myocardial oxygen demands may contribute to increased vulnerability to ischemia during exercise in the chronically pressureoverloaded hypertrophied left ventricle was tested. Myocardial oxygen consumption was
Publikováno v:
Circulation. 85(3)
BACKGROUND Exercise-induced dilation of coronary resistance vessels is limited by alpha-adrenergic mechanisms. However, the effect of alpha-adrenergic mechanisms on large coronary arteries during exercise is not known. METHODS AND RESULTS In the pres
Publikováno v:
Circulation. 85(1)
BACKGROUND Previous work has reported that coronary vasodilator reserve may persist in myocardium rendered ischemic by hypoperfusion. This study investigated the presence and extent of residual coronary vasomotor tone in myocardial regions made acute
Publikováno v:
Circulation research. 69(3)
This study was performed to test the hypothesis that active constriction of coronary collateral vessels can worsen hypoperfusion of collateral-dependent myocardium during exercise. Studies were performed in seven adult mongrel dogs in which intermitt