Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Xue-Yuan Bi"'
Publikováno v:
Neural Regeneration Research, Vol 17, Iss 5, Pp 1080-1087 (2022)
Baicalin is a natural active ingredient isolated from Scutellariae Radix that can cross the blood-brain barrier and exhibits neuroprotective effects on multiple central nervous system diseases. However, the mechanism behind the neuroprotective effect
Externí odkaz:
https://doaj.org/article/ad4b8decb60a45a3afa242ca59d2ae16
Autor:
Yong-Hua Yang, Dong-Ling Li, Xue-Yuan Bi, Lei Sun, Xiao-Jiang Yu, Huan-Le Fang, Yi Miao, Ming Zhao, Xi He, Jin-Jun Liu, Wei-Jin Zang
Publikováno v:
Cellular Physiology and Biochemistry, Vol 36, Iss 5, Pp 2025-2038 (2015)
Background: Excessive activation of matrix metalloproteinase 9 (MMP-9) has been found in several inflammatory diseases. Previous studies have shown that acetylcholine (ACh) reduced the levels of pro-inflammatory cytokines and decreased tissue damage.
Externí odkaz:
https://doaj.org/article/533e612514d24fb89de7d2197d15325d
Autor:
Ming Zhao, Xi He, Yong-Hua Yang, Xiao-Jiang Yu, Xue-Yuan Bi, Yang Yang, Man Xu, Xing-Zhu Lu, Qiang Sun, Wei-Jin Zang
Publikováno v:
Journal of Pharmacological Sciences, Vol 127, Iss 4, Pp 481-488 (2015)
The Ca2+-sensing receptor (CaSR) plays an important role in regulating vascular tone. In the present study, we investigated the positive effects of the vagal neurotransmitter acetylcholine by suppressing CaSR activation in mesenteric arteries exposed
Externí odkaz:
https://doaj.org/article/ba902d49b6ad4b1582dee676ee0cd0ba
Publikováno v:
Oxidative Medicine and Cellular Longevity, Vol 2021 (2021)
Oxidative Medicine and Cellular Longevity
Oxidative Medicine and Cellular Longevity
Angiotensin II- (Ang II-) induced cardiac hypertrophy and apoptosis are major characteristics of early-stage heart failure. Choline exerts cardioprotective effects; however, its effects on Ang II-induced cardiomyocyte apoptosis are unclear. In this s
Publikováno v:
Neural Regeneration Research
Neural Regeneration Research, Vol 17, Iss 5, Pp 1080-1087 (2022)
Neural Regeneration Research, Vol 17, Iss 5, Pp 1080-1087 (2022)
Baicalin is a natural active ingredient isolated from Scutellariae Radix that can cross the blood-brain barrier and exhibits neuroprotective effects on multiple central nervous system diseases. However, the mechanism behind the neuroprotective effect
Autor:
Xi He, Long-Zhu Liu, Hang-Huan Jia, Xiao-Jiang Yu, Xue-Yuan Bi, Ming Zhao, Man Xu, Wei-Jin Zang
Publikováno v:
Journal of Molecular and Cellular Cardiology. 107:1-12
The endoplasmic reticulum (ER) forms discrete junctions with the plasma membrane (PM) that play a critical role in the regulation of Ca2+ signaling during cellular bioenergetics, apoptosis and autophagy. We have previously confirmed that acetylcholin
Publikováno v:
Cell Cycle. 15:1331-1343
The mitochondrial unfolded protein response (UPR(mt)) is involved in numerous diseases that have the common feature of mitochondrial dysfunction. However, its pathophysiological relevance in the context of hypoxia/reoxygenation (H/R) in endothelial c
Autor:
Ming Zhao, Zhenghang Zhao, Xing-Zhu Lu, Xi He, Xue-Yuan Bi, Xiao-Jiang Yu, Man Xu, Wei-Jin Zang
Publikováno v:
British Journal of Pharmacology. 172:5619-5633
Background and Purpose The activation of M3 cholinoceptors (M3 receptors) by choline reduces cardiovascular risk, but it is unclear whether these receptors can regulate ischaemia/reperfusion (I/R)-induced vascular injury. Thus, the primary goal of th
Publikováno v:
British Journal of Pharmacology. 172:5489-5500
Cardiovascular disease remains a major cause of disability and death worldwide. Autonomic imbalance, characterized by suppressed vagal (parasympathetic) activity and increased sympathetic activity, correlates with various pathological conditions, inc
Publikováno v:
Cellular Physiology and Biochemistry, Vol 36, Iss 5, Pp 1877-1889 (2015)
Background: Previous studies have shown that inflammation is associated with excessive activation of calpains. Acetylcholine (ACh) has been reported to inhibit pro-inflammatory cytokine release and protect against cardiomyocyte injury. However, there