Zobrazeno 1 - 10
of 209
pro vyhledávání: '"Xue-Song Liu"'
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Rapid tissue reconstruction in acute and chronic injuries are challengeable, the inefficient repair mainly due to the difficulty in simultaneous promoting the regeneration of peripheral nerves and vascular, which are closely related. Main clinical me
Externí odkaz:
https://doaj.org/article/80e349a59cf440058c1f53cd0e82edae
Autor:
Huizi Yao, Huimin Li, Jinyu Wang, Tao Wu, Wei Ning, Kaixuan Diao, Chenxu Wu, Guangshuai Wang, Ziyu Tao, Xiangyu Zhao, Jing Chen, Xiaoqin Sun, Xue-Song Liu
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-9 (2023)
Abstract Homologous recombination deficiency (HRD) renders cancer cells vulnerable to unrepaired double-strand breaks and is an important therapeutic target as exemplified by the clinical efficacy of poly ADP-ribose polymerase (PARP) inhibitors as we
Externí odkaz:
https://doaj.org/article/1f63b5cba046492882bba12a5b3b38cb
Autor:
Shengmiao Chen, Yiran Wu, Yang Gao, Chenxu Wu, Yuetong Wang, Chun Hou, Miao Ren, Shuyuan Zhang, Qi Zhu, Jiali Zhang, Yufeng Yao, Mei Huang, Yingchuan B. Qi, Xue-Song Liu, Tiffany Horng, Haopeng Wang, Dan Ye, Zhengjiang Zhu, Suwen Zhao, Gaofeng Fan
Publikováno v:
Cell Reports, Vol 42, Iss 10, Pp 113246- (2023)
Summary: Metastasis is the leading cause of high ovarian-cancer-related mortality worldwide. Three major processes constitute the whole metastatic cascade: invasion, intravasation, and extravasation. Tumor cells often reprogram their metabolism to ga
Externí odkaz:
https://doaj.org/article/73673cf421364316ac4c841bac00308d
Publikováno v:
Journal of Materiomics, Vol 8, Iss 2, Pp 417-426 (2022)
To repair the damaged SiC coated C/C composites, a double-layer system including a Sm-doped borosilicate glass external layer and a SiSiC inner layer was prepared by a slurry-based laser cladding technique. Isothermal oxidation experiment and indi
Externí odkaz:
https://doaj.org/article/0752a5dd92374571b2bcd9acc678dac0
Autor:
Tao Wu, Chenxu Wu, Xiangyu Zhao, Guangshuai Wang, Wei Ning, Ziyu Tao, Fuxiang Chen, Xue-Song Liu
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-9 (2022)
Abstract Extrachromosomal DNA (ecDNA) is a type of circular and tumor specific genetic element. EcDNA has been reported to display open chromatin structure, facilitate oncogene amplification and genetic material unequal segregation, and is associated
Externí odkaz:
https://doaj.org/article/284f8eec28c04dd1a6e6f6ad601b9232
Autor:
Zaoke He, Shixiang Wang, Yuanyuan Shao, Jing Zhang, Xiaolin Wu, Yuxing Chen, Junhao Hu, Feng Zhang, Xue-Song Liu
Publikováno v:
iScience, Vol 19, Iss , Pp 256-266 (2019)
Summary: How cells adapt to oncogenic transformation-associated cellular stress and become fully transformed is still unknown. Here we identified a novel GGCT-regulated glutathione (GSH)-reactive oxygen species (ROS) metabolic pathway in oncogenic st
Externí odkaz:
https://doaj.org/article/0364abf8b7264d9db0e5ea4803526d46
Autor:
Shixiang Wang, Huimin Li, Minfang Song, Ziyu Tao, Tao Wu, Zaoke He, Xiangyu Zhao, Kai Wu, Xue-Song Liu
Publikováno v:
PLoS Genetics, Vol 17, Iss 5, p e1009557 (2021)
Genome alteration signatures reflect recurring patterns caused by distinct endogenous or exogenous mutational events during the evolution of cancer. Signatures of single base substitution (SBS) have been extensively studied in different types of canc
Externí odkaz:
https://doaj.org/article/1e78079d509c4c58b50c697b1489ca60
Autor:
Zaoke He, Tao Wu, Shixiang Wang, Jing Zhang, Xiaoqin Sun, Ziyu Tao, Xiangyu Zhao, Huimin Li, Kai Wu, Xue-Song Liu
Publikováno v:
iScience, Vol 24, Iss 4, Pp 102285- (2021)
Summary: Noncoding DNA sequences occupy more than 98% of the human genome; however, few cancer noncoding drivers have been identified compared with cancer coding drivers, probably because cancer noncoding drivers have a distinct mutation pattern due
Externí odkaz:
https://doaj.org/article/7e6ca8b3a2974b96adcaafec40c00917
Autor:
Xue-song Liu, Jing Zeng, Yu-xue Yang, Chun-lei Qi, Ting Xiong, Geng-ze Wu, Chun-yu Zeng, Da-xin Wang
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2021)
Ischemia-reperfusion (I/R) could cause heart irreversible damage, which is tightly combined with glucose metabolism disorder. It is demonstrated that GLUT4 (glucose transporter 4) translocation is critical for glucose metabolism in the cardiomyocytes
Externí odkaz:
https://doaj.org/article/65a1fcd59d27421c8e42fa637e2ceabb
Publikováno v:
eLife, Vol 8 (2019)
Immunotherapy, represented by immune checkpoint inhibitors (ICI), is transforming the treatment of cancer. However, only a small percentage of patients show response to ICI, and there is an unmet need for biomarkers that will identify patients who ar
Externí odkaz:
https://doaj.org/article/09cbc904da4e4bf9815261157371e136