Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Xue-Qin Yao"'
Autor:
Jiang Lu, Xue-qin Yao, Xin Luo, Yu Wang, Sookja Kim Chung, He-xin Tang, Chi Wai Cheung, Xian-yu Wang, Chen Meng, Qing Li
Publikováno v:
Neural Regeneration Research, Vol 12, Iss 6, Pp 945-952 (2017)
Monosialoganglioside 1 (GM1) is the main ganglioside subtype and has neuroprotective properties in the central nervous system. In this study, we aimed to determine whether GM1 alleviates neurotoxicity induced by moderate and high concentrations of pr
Externí odkaz:
https://doaj.org/article/4ddd3f0fe18f47349b369b03b567aea4
Autor:
Shao-Chen Cheng, Chun-Bing Liu, Xue-Qin Yao, Jing-Yang Hu, Ting-Ting Yin, Burton K Lim, Wu Chen, Guo-Dong Wang, Cheng-Lin Zhang, David M Irwin, Zhi-Gang Zhang, Ya-Ping Zhang, Li Yu
Publikováno v:
National Science Review. 10
Highly specialized myrmecophagy (ant- and termite-eating) has independently evolved multiple times in species of various mammalian orders and represents a textbook example of phenotypic evolutionary convergence. We explored the mechanisms involved in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::229f21e9342455e384df0ed2091d54b6
https://doi.org/10.1093/nsr/nwac174
https://doi.org/10.1093/nsr/nwac174
Publikováno v:
Anesthesia and analgesia. 130(2)
BACKGROUND A prolonged exposure to ketamine triggers significant neurodegeneration and long-term neurocognitive deficits in the developing brain. Monosialotetrahexosylganglioside (GM1) can limit the neuronal damage from necrosis and apoptosis in neur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47bacf73cc2a1f022e9dec681ac38dad
https://pubmed.ncbi.nlm.nih.gov/31934908
https://pubmed.ncbi.nlm.nih.gov/31934908
Autor:
Chi Wai Cheung, Sookja K. Chung, Xue-qin Yao, Xin Luo, Qing Li, He-xin Tang, Wang Yu, Chen Meng, Jiang Lu, Xianyu Wang
Publikováno v:
Neural Regeneration Research
Neural Regeneration Research, Vol 12, Iss 6, Pp 945-952 (2017)
Neural Regeneration Research, Vol 12, Iss 6, Pp 945-952 (2017)
Monosialoganglioside 1 (GM1) is the main ganglioside subtype and has neuroprotective properties in the central nervous system. In this study, we aimed to determine whether GM1 alleviates neurotoxicity induced by moderate and high concentrations of pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f18f7e3b906f5e842a9d99ce6907d407
http://europepmc.org/articles/PMC5514870
http://europepmc.org/articles/PMC5514870
Publikováno v:
European Journal of Pharmaceutics and Biopharmaceutics. 72:405-411
Interferon-alpha2b (IFN-alpha2b) and human serum albumin (HSA) fusion protein (IFN-alpha2b-HSA) is a promising long acting formulation of IFN-alpha2b for the treatment of hepatitis C. However, accelerated mechanical and thermal stress tests revealed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e5c434e3e24e58b60dbbece12854f99
https://doi.org/10.1016/j.ejpb.2009.01.008
https://doi.org/10.1016/j.ejpb.2009.01.008
Publikováno v:
FEMS Yeast Research. 9:591-599
Onconase, an RNAse extracted from embryos of the Northern leopard frog (Rana pipiens), is in a confirmatory phase IIIb clinical trial for the treatment of unresectable malignant mesothelioma. Because the current purification process for onconase is c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7767ed5fcba9f0a165c5310d04b14d54
https://doi.org/10.1111/j.1567-1364.2009.00498.x
https://doi.org/10.1111/j.1567-1364.2009.00498.x
Autor:
Zhi-Min Liu, Zhi Wei Wang, Xiang Hua Xiong, Xian Yu Li, Wei Zhang, Hongliang Zhao, Chong Xue, Xue Qin Yao
Publikováno v:
Journal of Biotechnology. 139:131-136
Expression of recombinant protein HSA-AX15(R13K) in Pichia pastoris GS115 strain produced both the intact protein and its two degradation products with molecular weights of around 43 kDa and 66.2 kDa, respectively. To reduce or avoid the degradation,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1cc42119ce3698990b0805cdeb860601
https://doi.org/10.1016/j.jbiotec.2008.09.006
https://doi.org/10.1016/j.jbiotec.2008.09.006
Publikováno v:
Applied Microbiology and Biotechnology. 81:235-241
In this study, we assessed the potential of PMR1-disrupted Pichia pastoris (Pppmr1) expressing human serum albumin and interferon alpha 2b fusion protein (HSA-IFN-alpha 2b) in large-scale fermentation. The high osmotic pressure of standard basal salt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c7148e989cb7b26a02524db390e5b2a
https://doi.org/10.1007/s00253-008-1666-0
https://doi.org/10.1007/s00253-008-1666-0
Autor:
Hui-Peng Chen, Xiang-Hua Xiong, Xian-yu Li, Wei Zhang, Xue-qin Yao, Zhi-Min Liu, Hongliang Zhao, Chong Xue
Publikováno v:
Biotechnology Progress. 22:1090-1095
In Pichia pastoris, secretory proteins are folded and assembled in the endoplasmic reticulum (ER). However, upon introduction of foreign proteins, heterologous proteins are often retained in the cytoplasm or in the ER as a result of suboptimal foldin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b26b5aafb96a5b97af92f6ac67c96092
https://doi.org/10.1021/bp060019r
https://doi.org/10.1021/bp060019r
Autor:
Hao Wu, Quan-Hong Ma, De-En Xu, Ke Yan, Ruxiang Xu, Xue-qin Yao, Chun-Feng Liu, Liang-feng Fan, Weihua Wang
Publikováno v:
Neuroscience letters. 548
Contactin associated protein (Caspr), an adhesion molecule, plays roles in formation of paranodal junctions in myelinated axons, neurite outgrowth, synaptic plasticity in nervous system. Here we have shown a novel function of Caspr in pathogenesis of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::291f81f8680e1f3de2b4a82e790af61d
https://pubmed.ncbi.nlm.nih.gov/23748076
https://pubmed.ncbi.nlm.nih.gov/23748076