Zobrazeno 1 - 10
of 154
pro vyhledávání: '"Xue-Qian Zhang"'
Publikováno v:
BMC Neurology, Vol 17, Iss 1, Pp 1-4 (2017)
Abstract Background Uremic Encephalopathy (UE) is a neurological complication associated with acute or chronic renal failure. Imaging findings of UE may present involvement of the basal ganglia, cortical or subcortical regions, and white matter. We r
Externí odkaz:
https://doaj.org/article/98805ed3a7b24b5dba9642b52b34b049
Autor:
Tijana Knezevic, PhD, Valerie D. Myers, MS, Feifei Su, MD, PhD, JuFang Wang, MD, Jianliang Song, MD, PhD, Xue-Qian Zhang, MD, Erhe Gao, MD, PhD, Guofeng Gao, MD, PhD, Muniswamy Madesh, PhD, Manish K. Gupta, PhD, Jennifer Gordon, PhD, Kristen N. Weiner, BS, Joseph Rabinowitz, PhD, Frederick V. Ramsey, PhD, Douglas G. Tilley, PhD, Kamel Khalili, PhD, Joseph Y. Cheung, MD, PhD, Arthur M. Feldman, MD, PhD
Publikováno v:
JACC: Basic to Translational Science, Vol 1, Iss 7, Pp 647-656 (2016)
Mutations in Bcl-2–associated athanogene 3 (BAG3) were associated with skeletal muscle dysfunction and dilated cardiomyopathy. Retro-orbital injection of an adeno-associated virus serotype 9 expressing BAG3 (rAAV9-BAG3) significantly (p < 0.0001) i
Externí odkaz:
https://doaj.org/article/70f170720da34f2985f48ff26cb0cbfd
Autor:
Eman A Hamad, Weizhong Zhu, Tung O Chan, Valerie Myers, Erhe Gao, Xue Li, Jin Zhang, Jianliang Song, Xue-Qian Zhang, Joseph Y Cheung, Walter Koch, Arthur M Feldman
Publikováno v:
PLoS ONE, Vol 7, Iss 7, p e39919 (2012)
Adenosine binds to three G protein-coupled receptors (R) located on the cardiomyocyte (A(1)-R, A(2A)-R and A(3)-R) and provides cardiac protection during both ischemic and load-induced stress. While the role of adenosine receptor-subtypes has been we
Externí odkaz:
https://doaj.org/article/7d45b07a782940a28b938ae5ecdfddf9
Publikováno v:
Chemistry & Biodiversity. 20
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b779a7321264601d07cd2f082caf9a58
https://doi.org/10.1002/cbdv.202300230
https://doi.org/10.1002/cbdv.202300230
Autor:
Joseph Y. Cheung, Jianliang Song, Kamel Khalili, Arthur M. Feldman, Jennifer Gordon, Xue-Qian Zhang, Dhanendra Tomar, JuFang Wang, Glenn S. Gerhard, Valerie D. Myers
Publikováno v:
J Card Fail
Background We reported 3 novel nonsynonymous single nucleotide variants of Bcl2-associated athanogene 3 (BAG3) in African Americans with heart failure (HF) that are associated with a 2-fold increase in cardiac events (HF hospitalization, heart transp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33c8dceea7f8ef1385f509265b0a973f
https://doi.org/10.1016/j.cardfail.2020.09.009
https://doi.org/10.1016/j.cardfail.2020.09.009
Autor:
Kerry Keefer, Iwona Hirschler-Laszkiewicz, Xue-Qian Zhang, Joseph Y. Cheung, Salim Merali, Sinisa Dovat, Barbara A. Miller, Longgui Chen, JuFang Wang, Hong Gang Wang, Carmen Merali, Yuka Imamura, Muniswamy Madesh, Santhanam Shanmughapriya, Shu Jen Chen, Lei Bao, John P. Lee
Publikováno v:
Cell Death and Disease, Vol 11, Iss 4, Pp 1-17 (2020)
Cell Death & Disease
Cell Death & Disease
Transient receptor potential melastatin 2 (TRPM2) ion channel has an essential function in maintaining cell survival following oxidant injury. Here, we show that TRPM2 is highly expressed in acute myeloid leukemia (AML). The role of TRPM2 in AML was
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e1d5d4c50e8d793130ba517d18c224b
http://link.springer.com/article/10.1038/s41419-020-2454-8
http://link.springer.com/article/10.1038/s41419-020-2454-8
Autor:
Muniswamy Madesh, Sudasan Rajan, Santhanam Shanmughapriya, Shey-Shing Sheu, Barbara A. Miller, Xue-Qian Zhang, Iwona Hirschler-Laszkiewicz, Arthur M. Feldman, Jianliang Song, JuFang Wang, Dhanendra Tomar, Joseph Y. Cheung
Publikováno v:
J Cell Physiol
The mechanisms by which Trpm2 channels enhance mitochondrial bioenergetics and protect against oxidative stress-induced cardiac injury remain unclear. Here, the role of proline-rich tyrosine kinase 2 (Pyk2) in Trpm2 signaling is explored. Activation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::437058565ecca09f98335bbef742a58d
https://doi.org/10.1002/jcp.28146
https://doi.org/10.1002/jcp.28146
Autor:
Sudarsan Rajan, Santhanam Shanmughapriya, Erhe Gao, Hong Wang, Rajika Roy, Xue-Qian Zhang, Sarah M. Schumacher, Jianliang Song, Dhanendra Tomar, Joseph Y. Cheung, Walter J. Koch
Publikováno v:
Circulation Research. 127
Cardiac contractility is regulated by the intracellular Ca 2+ concentration fluxes which are actively regulated by multiple channels and transporters. Ca 2+ uptake into the mitochondrial matrix is precisely controlled by the highly Ca 2+ selective ch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::26b4d7f33e21ab21fdfa671efc8b41a6
https://doi.org/10.1161/res.127.suppl_1.381
https://doi.org/10.1161/res.127.suppl_1.381
Autor:
Kerry Keefer, Santhanam Shanmughapriya, Iwona Hirschler-Laszkiewicz, Muniswamy Madesh, Lei Bao, Shu Jen Chen, JuFang Wang, Xue-Qian Zhang, Joseph Y. Cheung, Barbara A. Miller
Publikováno v:
American Journal of Physiology-Cell Physiology
Transient receptor potential melastatin channel subfamily member 2 (TRPM2) has an essential function in cell survival and is highly expressed in many cancers. Inhibition of TRPM2 in neuroblastoma by depletion with CRISPR technology or expression of d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4d874b689710b65268bc68b4e719ee9
https://doi.org/10.1152/ajpcell.00098.2018
https://doi.org/10.1152/ajpcell.00098.2018
Autor:
Fabian Jana Prado, Nana Merabova, Manish K. Gupta, Joseph M. McClung, Joseph Y. Cheung, Jennifer Gordon, Jianliang Song, Xue-Qian Zhang, Santhanam Shanmughapriya, Sudarsan Rajan, Kamel Khalili, Christopher D. Kontos, Tijana Knezevic, Muniswamy Madesh, Dhanendra Tomar, Arthur M. Feldman, Farzaneh G. Tahrir, Paul E. Klotman, JuFang Wang
Publikováno v:
Journal of Cellular Physiology. 234:4432-4444
The pathophysiology of human immunodeficiency virus (HIV)-associated cardiomyopathy remains uncertain. We used HIV-1 transgenic (Tg26) mice to explore mechanisms by which HIV-related proteins impacted on myocyte function. Compared to adult ventricula
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c110500a88c27736aa5876092e280f6e
https://doi.org/10.1002/jcp.27232
https://doi.org/10.1002/jcp.27232