Zobrazeno 1 - 10
of 90
pro vyhledávání: '"Xue-Nong Zhang"'
Autor:
Yan Wang, Yun-hui Zhang, Yin-ru Tang, Jie Lan, Zhi-ying Huang, Wei Tian, Qian Huang, Yan Peng, Yuan Gao, Yue-qin Hu, Xue-nong Zhang
Publikováno v:
Iranian Journal of Basic Medical Sciences, Vol 25, Iss 3, Pp 414-418 (2022)
Objective(s): Cisplatin (CDDP) is a highly effective chemotherapeutic agent, but its clinical application has been limited by nephrotoxicity. Tanshinone Ⅰ (T-I), a phenanthrenequinone compound extracted from the Chinese herb Danshen, has been used
Externí odkaz:
https://doaj.org/article/4a6ef5b1217c418b9de681913c8cf48e
Autor:
Yu, Wang, Yan, Tang, Xiao-Mei, Zhao, Gui, Huang, Jin-Hong, Gong, Shu-di, Yang, Hui, Li, Wen-Jun, Wan, Chang-Hao, Jia, Gang, Chen, Xue-Nong, Zhang
Publikováno v:
Acta Biomaterialia. 153:481-493
Clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR-associated protein 9 (Cas9) system adapted from bacteria is a programmable nuclease-based genome editing tool. The long-lasting effect of gene silencing or correction is benefi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e31032d33f23349232405bd110e2e31
https://doi.org/10.1016/j.actbio.2022.09.046
https://doi.org/10.1016/j.actbio.2022.09.046
Autor:
Wen-jun Wan, Ben-gang You, Xue-nong Zhang, Yu Wang, Meng-tian Chen, Ye-juan Zhou, Yao Tong, Yang Liu, Dan-dan Wang
Publikováno v:
Journal of Biomedical Materials Research Part B: Applied Biomaterials. 108:1710-1724
Cancer cells have been reported to exhibit high resistance against immune system recognition through various cell intrinsic and extrinsic mechanisms. Considerable challenges have been encountered in monotherapy with chemotherapeutics to attain the de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6085068fc811a94d05c1d93bb67079a3
https://doi.org/10.1002/jbm.b.34516
https://doi.org/10.1002/jbm.b.34516
Autor:
Wei-liang Chen, Chen-xi Qu, Xue-nong Zhang, Yang Liu, Dan-dan Wang, Meng-tian Chen, Yu Wang, Ye-juan Zhou, Fang Li, Ben-gang You, Shu-di Yang
Publikováno v:
Theranostics
Targeting tumor angiogenesis pathway via VEGF siRNA (siVEGF) has shown great potential in treating highly malignant and metastatic non-small cell lung cancer (NSCLC). However, anti-angiogenic monotherapy lacked sufficient antitumor efficacy which suf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6030a4656780654df8a20f7dd9ebe14a
http://europepmc.org/articles/PMC6735374
http://europepmc.org/articles/PMC6735374
Autor:
Ye-juan Zhou, Wen-jun Wan, Ben-gang You, Xue-nong Zhang, Chen-xi Qu, Fang Li, Liang Zhang, Meng-tian Chen, Yang Liu, Dan-dan Wang
Publikováno v:
International Journal of Pharmaceutics. 566:731-744
Tumor cells avoid immunosurveillance during the tumorigenesis, metastasis and recurrence periods thanks to the overexpressed immunosuppressive molecules on their surface. For instance, the programmed cell death 1 ligand (PD-L1) binds with the T-cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::403c0098062bccf952f4b1b9fdad64db
https://doi.org/10.1016/j.ijpharm.2019.06.030
https://doi.org/10.1016/j.ijpharm.2019.06.030
Publikováno v:
Advanced healthcare materials. 10(19)
Lactate, as the most abundant component with concentrations of 4-40 mm in tumors, contributes to the regulation of metabolic pathways, angiogenesis, and immunosuppression, exhibiting remarkable potential in cancer treatment. Therefore, a codelivery s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f54d11e29a0732a7d7808de1ceffe515
https://pubmed.ncbi.nlm.nih.gov/34310079
https://pubmed.ncbi.nlm.nih.gov/34310079
Autor:
Dan-dan Wang, Xue-nong Zhang
Publikováno v:
Journal of controlled release : official journal of the Controlled Release Society. 333
Tumor-sensitivity, effective transport, and precise delivery to tumor cells of nano drug delivery systems (NDDs) have been great challenges to cancer therapy in recent years. The conventional targeting approach involves actively installing the corres
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fae590e64e3f7511cc9e6b3174f4422c
https://pubmed.ncbi.nlm.nih.gov/33812919
https://pubmed.ncbi.nlm.nih.gov/33812919
Autor:
Yao Tong, Wen-jun Wan, Han Yang, Beng-gang You, Yu Wang, Xue-nong Zhang, Dan-dan Wang, Yang Liu
Backgroud: Gene therapy has attracted widespread attention as a potential method of treating some autoimmune diseases, genetic diseases and cancer. It is critical to discover a new nanocarrier for the effectiveness of gene therapy. Reportedly, the du
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3153730eb560fbc1915cbe0d556c4e9d
https://doi.org/10.21203/rs.3.rs-20688/v1
https://doi.org/10.21203/rs.3.rs-20688/v1
Autor:
Ying Wang, Yang Liu, Ben-gang You, Chen-xi Qu, Wei-liang Chen, Meng-tian Chen, Xue-nong Zhang, Zhaoxiang Ren, Shu-di Yang
Publikováno v:
Molecular Pharmaceutics. 15:314-325
In this article, a novel graft polymeric micelle with targeting function ground on aptamer AS1411 was synthesized. The micelle was based on chitosan-ss-polyethylenimine-urocanic acid (CPU) with dual pH/redox sensitivity and targeting effects. This mi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::568cd791d69a2a12301cdf676676b256
https://doi.org/10.1021/acs.molpharmaceut.7b01093
https://doi.org/10.1021/acs.molpharmaceut.7b01093
Publikováno v:
Materials Science and Engineering: C. 119:111583
Acute myeloid leukemia (AML) is the most universal type and fatal disease of hematological malignancy, with poor outcomes despite chemotherapy and bone marrow transplantations. Benefited from the narrow tissue specificity of folate receptor β (FRβ)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c327d9d14fd48ba4b6759dc77ae8f66c
https://doi.org/10.1016/j.msec.2020.111583
https://doi.org/10.1016/j.msec.2020.111583