Zobrazeno 1 - 10
of 166
pro vyhledávání: '"Xue-Long Sun"'
Autor:
Darong Yang, Yin Wu, Isaac Turan, Joseph Keil, Kui Li, Michael H. Chen, Runhua Liu, Lizhong Wang, Xue-Long Sun, Guo-Yun Chen
Publikováno v:
iScience, Vol 26, Iss 2, Pp 106037- (2023)
Summary: There are currently no effective therapies for COVID-19 or antivirals against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), and vaccines appear less effective against new SARS-CoV-2 variants; thus, there is an urgent need to
Externí odkaz:
https://doaj.org/article/3ceac4db3a8144b78fcc6670dab8a7a4
Publikováno v:
TH Open, Vol 06, Iss 03, Pp e194-e212 (2022)
Thrombomodulin (TM) is a type-I transmembrane protein that is mainly expressed on endothelial cells and plays important roles in many biological processes. Circulating TM of different forms are also present in biofluids, such as blood and urine. Solu
Externí odkaz:
https://doaj.org/article/d6a54f1fb7594c6c8df508ddd863aaad
Publikováno v:
Frontiers in Chemistry, Vol 10 (2022)
Glyconanomaterials with unique nanoscale property and carbohydrate functionality show vast potential in biological and biomedical applications. We investigated the interactions of noncovalent complexes of single-wall carbon nanotubes that are wrapped
Externí odkaz:
https://doaj.org/article/4183eb591f364563b4d46db70976406c
Publikováno v:
ACS Omega, Vol 3, Iss 10, Pp 13467-13473 (2018)
Externí odkaz:
https://doaj.org/article/19c3d734c97141cc8fc4f3edf3b6bdec
Publikováno v:
ACS Omega, Vol 3, Iss 2, Pp 1589-1599 (2018)
Externí odkaz:
https://doaj.org/article/90dad7f2b0934ff999804ca773e0a855
Publikováno v:
eLife, Vol 7 (2018)
Trypsin-like serine proteases are essential in physiological processes. Studies have shown that N-glycans are important for serine protease expression and secretion, but the underlying mechanisms are poorly understood. Here, we report a common mechan
Externí odkaz:
https://doaj.org/article/af6dfb7321534943aa63062998d2a98b
Publikováno v:
Biochemical and Biophysical Research Communications. 651:79-84
Autor:
Joseph M. Keil, Garrett R. Rafn, Isaac M. Turan, Majdi A. Aljohani, Reza Sahebjam-Atabaki, Xue-Long Sun
Publikováno v:
Journal of Medicinal Chemistry. 65:13574-13593
Sialidases, or neuraminidases, are enzymes that catalyze the hydrolysis of sialic acid (Sia)-containing molecules, mostly removal of the terminal Sia (desialylation). By desialylation, sialidase can modulate the functionality of the target compound a
Autor:
Darong Yang, Yin Wu, Isaac Turan, Joseph Keil, Kui Li, Michael H. Chen, Runhua Liu, Lizhong Wang, Xue-Long Sun, Guo-Yun Chen
SummaryThere are no effective therapies for COVID-19 or antivirals against SARS-CoV-2. Furthermore, current vaccines appear less efficacious for new SARS-CoV-2 variants. Thus, there is an urgent need to better understand the virulence mechanisms of S
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b55fecd5bcf736e541f9ae874fc5eeed
https://doi.org/10.1101/2022.09.09.507342
https://doi.org/10.1101/2022.09.09.507342
Autor:
Xue-Long Sun
Publikováno v:
Glycobiology. 31:1245-1253
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is a new virus that has higher contagious capacity than any other previous human coronaviruses (HCoVs) and causes the current coronavirus disease 2019 pandemic. Sialic acids are a group of