Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Xue-Kang Zhang"'
Autor:
Qin Zhang, Xiao-Ming Liu, Qian Hu, Zheng-Ren Liu, Zhi-Yi Liu, Huai-Gen Zhang, Yuan-Lu Huang, Qiu-Hong Chen, Wen-Xiang Wang, Xue-Kang Zhang
Publikováno v:
Journal of Translational Medicine, Vol 19, Iss 1, Pp 1-16 (2021)
Abstract Background Intestinal ischemia/reperfusion (I/R) injury commonly occurs during perioperative periods, resulting in high morbidity and mortality on a global scale. Dexmedetomidine (Dex) is a selective α2-agonist that is frequently applied du
Externí odkaz:
https://doaj.org/article/3750b758684f4261b250b532b1bfc6e8
Publikováno v:
Iranian Journal of Basic Medical Sciences, Vol 18, Iss 6, Pp 604-609 (2015)
Objective(s): Intestinal ischemia-reperfusion is a major problem, which may lead to multiorgan failure and death. The aim of this study was to evaluate the protective effects of dexmedetomidine on cell proliferation, antioxidant system, cell death, a
Externí odkaz:
https://doaj.org/article/78955537597542baa592c68fcf728b02
Autor:
Zhen Liu, Kai Hu, Yue-Sheng Chen, Ying-Jie Huang, Qian Hu, Wei Zeng, Yue Cao, Qin Xiao, Xue-Kang Zhang
Publikováno v:
Molecular Biology Reports. 49:2857-2867
Intestinal ischemia-reperfusion (I/R) causes severe injury to the intestine, leading to systemic inflammation and multiple organ failure. Autophagy is a stress-response mechanism that can protect against I/R injury by removing damaged organelles and
Autor:
Kun Yu, Xue-Kang Zhang, Han-Chun Xiong, Si-Si Liang, Zi-Yun Lu, Yong-Qiang Wu, Yu Chen, Su-Jun Xiao
Publikováno v:
Neuroscience Letters. 807:137259
Autor:
Qin Zhang, Qian Hu, Zheng-Ren Liu, Xue-Kang Zhang, Yuan-Lu Huang, Huai-Gen Zhang, Wen-Xiang Wang, Jun Zhou, Qiu-Hong Chen
Publikováno v:
Journal of Nanoscience and Nanotechnology. 20:3295-3302
Dexmedetomidine (Dex) works as a crucial agent for the treatment of intestinal ischemia/reperfusion (I/R), but its mechanism remains unclear. Recent articles demonstrated the pivotal role of Janus kinase/signal transducer and activator of transcripti
Autor:
Qiu-Hong Chen, Xiao-Ming Liu, Zhi-Yi Liu, Qin Zhang, Yuan-Lu Huang, Huai-Gen Zhang, Zheng-Ren Liu, Xue-Kang Zhang, Qian Hu, Wen-Xiang Wang
Publikováno v:
Journal of Translational Medicine
Journal of Translational Medicine, Vol 19, Iss 1, Pp 1-16 (2021)
Journal of Translational Medicine, Vol 19, Iss 1, Pp 1-16 (2021)
Background Intestinal ischemia/reperfusion (I/R) injury commonly occurs during perioperative periods, resulting in high morbidity and mortality on a global scale. Dexmedetomidine (Dex) is a selective α2-agonist that is frequently applied during peri
Publikováno v:
Journal of Cellular and Molecular Medicine
Intestinal ischaemia‐reperfusion (I/R) injury can result in acute lung injury due to ischaemia and hypoxia. Dexmedetomidine (Dex), a highly selective alpha2‐noradrenergic receptor (α2AR) agonist used in anaesthesia, is reported to regulate infla
Autor:
Qian Hu, Qiu-Hong Chen, Lin Xu, Fo-Quan Lou, Si-Si Liang, Qiong Wu, Wen-Xiang Wang, Xue-Kang Zhang, Hai-Jin Huang
Publikováno v:
Neuroscience Letters. 677:110-116
Recently, growing evidence has demonstrated Dexmedetomidine (Dex) a promising intervene preventing postoperative cognitive decline (POCD) following surgery, which is associated with neuroinflammation leading to neuronal apoptosis and deregulated neur
Autor:
Qian Hu, Wen-Xiang Wang, Zheng-Ren Liu, Qin Zhang, Wei-Wu Deng, Huai-Gen Zhang, Xue-Kang Zhang, Yuan-Lu Huang, Qiu-Hong Chen
Publikováno v:
Molecular and Cellular Biochemistry. 449:81-90
Resistance to radiotherapy is a major limitation for the successful treatment of colorectal cancer (CRC). Recently, accumulating evidence supports a critical role of epigenetic regulation in tumor cell survival upon irradiation. Lysine Demethylase 4B
Autor:
Huai-Gen Zhang, Yuan-Lu Huang, Zheng-Ren Liu, Qin Zhang, Qiu-Hong Chen, Xue-Kang Zhang, Wen-Xiang Wang, Qian Hu, Xiao-Ming Liu, Zhi-Yi Liu
Publikováno v:
SSRN Electronic Journal.
Background: Intestinal ischemia-reperfusion injury (IRI) is a devastating complication in the perioperative period leading to systemic inflammation and multiple organ dysfunction. We aimed to determine whether dexmedetomidine protects against oxidati