Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Xue-Gang Yang"'
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
PurposeTo compare the efficacy and safety of transarterial chemoembolization (TACE) plus sorafenib and immune checkpoint inhibitors (T+S+ICIs) and TACE plus sorafenib (T+S) when treating patients with advanced hepatocellular carcinoma (HCC) who have
Externí odkaz:
https://doaj.org/article/e4a16aa7e4824007abe6c20e55647200
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
PurposeTo assess the effectiveness and safety of drug-eluting beads transarterial chemoembolization plus immune checkpoint inhibitors (DEB-TACE+ICIs) versus chemotherapy (gemcitabine+cisplatin) for patients with unresectable intrahepatic cholangiocar
Externí odkaz:
https://doaj.org/article/3323fc48cb254598a8ea9e9c08872d3a
Publikováno v:
Cancer investigation. 40(6)
To determine the predictive value of preoperative inflammatory markers in hepatocellular carcinoma (HCC) prognosis after transarterial chemoembolization (TACE) combined with radiofrequency ablation (RFA).A total of 161 patients with HCC who underwent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d351cf3d05586bd5374be70830e4896b
https://pubmed.ncbi.nlm.nih.gov/35404178
https://pubmed.ncbi.nlm.nih.gov/35404178
Publikováno v:
Chemometrics and Intelligent Laboratory Systems. 127:35-42
The quantitative structure–activity relationship (QSAR) for the prediction of the activity of two different scaffolds of 108 influenza neuraminidase A/PR/8/34 (H1N1) inhibitors was investigated. A feature selection method, which combines Genetic Al
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::abb732a5ca2249ec87b59c020cc0ac8c
https://doi.org/10.1016/j.chemolab.2013.05.012
https://doi.org/10.1016/j.chemolab.2013.05.012
Publikováno v:
Chemometrics and Intelligent Laboratory Systems. 101:95-101
Vasodilators have been extensively used in the treatment of various vascular diseases. With the aim of developing the accurate computational models for identifying vasodilators of diverse structures, several machine learning methods, such as C4.5 dec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::089442bfa329f1e8cc219ebe2bd6bd8d
https://doi.org/10.1016/j.chemolab.2010.02.001
https://doi.org/10.1016/j.chemolab.2010.02.001
Publikováno v:
Journal of Molecular Graphics and Modelling. 28:236-244
The inhibition of TNF-alpha converting enzyme (TACE) has been explored as a feasible therapy for the treatment of rheumatoid arthritis (RA) and Crohn's disease (CD). Recently, large numbers of novel and selective TACE inhibitors have been reported. I
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac279ee20c86259e43fe8e208c88e64a
https://doi.org/10.1016/j.jmgm.2009.08.001
https://doi.org/10.1016/j.jmgm.2009.08.001
Publikováno v:
QSAR & Combinatorial Science. 27:1028-1035
The human Ether-a-Go-Go-Related Gene (hERG) potassium ion channel plays a crucial role in cardiac repolarization. The inhibition of this channel by marketed drug may prolong the length of time between the start of Q wave and end of the T wave on an e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::af1e814c0a84e08a72dd49bc07ea457d
https://doi.org/10.1002/qsar.200810015
https://doi.org/10.1002/qsar.200810015
Publikováno v:
Computers in biology and medicine. 43(4)
We tested four machine learning methods, support vector machine (SVM), k-nearest neighbor, back-propagation neural network and C4.5 decision tree for their capability in predicting spleen tyrosine kinase (Syk) inhibitors by using 2592 compounds which
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34a833dd7ea8585293913a0d89130e28
https://pubmed.ncbi.nlm.nih.gov/23402937
https://pubmed.ncbi.nlm.nih.gov/23402937
Publikováno v:
Quantum Simulations of Materials and Biological Systems ISBN: 9789400749474
Factor Xa (FXa) is recognized as an attractive target for the design and development of new anticoagulant agents for combating the thromboembolic diseases. Recently, in silico prediction and screening approaches have been adopted as effective paradig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c0d4a26105bb6b017da5a74b7c8d8397
https://doi.org/10.1007/978-94-007-4948-1_8
https://doi.org/10.1007/978-94-007-4948-1_8
Publikováno v:
Journal of Computational Chemistry.
γ-Secretase inhibitors have been explored for the prevention and treatment of Alzheimer's disease (AD). Methods for prediction and screening of γ-secretase inhibitors are highly desired for facilitating the design of novel therapeutic agents agains
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa9e586f5be4228967b46aeb06f3d15a
https://doi.org/10.1002/jcc.21411
https://doi.org/10.1002/jcc.21411