Zobrazeno 1 - 10
of 291
pro vyhledávání: '"Xue Zhong, Liu"'
Autor:
LéShon Peart, Joanna Gonzalez, Dayna Morel Swols, Duygu Duman, Turcin Saridogan, Memoona Ramzan, Mohammad Faraz Zafeer, Xue Zhong Liu, Adrien A. Eshraghi, Michael E. Hoffer, Simon I. Angeli, Guney Bademci, Susan Blanton, Carson Smith, Fred F. Telischi, Mustafa Tekin
Publikováno v:
Human Genomics, Vol 17, Iss 1, Pp 1-10 (2023)
Abstract Background We analyzed the genetic causes of sensorineural hearing loss in racial and ethnic minorities of South Florida by reviewing demographic, phenotypic, and genetic data on 136 patients presenting to the Hereditary Hearing Loss Clinic
Externí odkaz:
https://doaj.org/article/ce2d44a8f2df49bea02b040f0748896b
Autor:
Jennifer Coto, Carmen L. Alvarez, Ivette Cejas, Brett M. Colbert, Bonnie E. Levin, Joshua Huppert, Tatjana Rundek, Carey Balaban, Susan H. Blanton, David J. Lee, David Loewenstein, Michael Hoffer, Xue Zhong Liu
Publikováno v:
Journal of Otology, Vol 16, Iss 4, Pp 258-265 (2021)
Given the interdependence of multiple factors in age-related vestibular loss (e.g., balance, vision, cognition), it is important to examine the individual contributions of these factors with ARVL. While the relationship between the vestibular and vis
Externí odkaz:
https://doaj.org/article/18ff8995579e44549f9c8d6d536450c5
Autor:
Rosemary Ida Kabahuma, Wolf‐Dieter Schubert, Christiaan Labuschagne, Denise Yan, Michael Sean Pepper, Xue‐Zhong Liu
Publikováno v:
Molecular Genetics & Genomic Medicine, Vol 10, Iss 10, Pp n/a-n/a (2022)
Abstract Background DFNB28, a recessively inherited nonsyndromic form of deafness in humans, is caused by mutations in the TRIOBP gene (MIM #609761) on chromosome 22q13. Its protein TRIOBP helps to tightly bundle F‐actin filaments, forming a rootle
Externí odkaz:
https://doaj.org/article/3432dc163ba648008a39bd6d1476a3f6
Autor:
Pei-Ciao Tang, Marie V Roche, Se Young Um, Nicholas C Gosstola, Min Young Kim, Byung Yoon Choi, Derek M Dykxhoorn, Xue Zhong Liu
Publikováno v:
Stem Cell Research, Vol 61, Iss , Pp 102758- (2022)
Hearing loss is one of the most common sensory disorders. TMEM43 is expressed in cochlear glia-like supporting cells (GLSs) and is known to be associated with late-onset auditory neuropathy spectrum disorder (ANSD) and progressive hearing loss. Here,
Externí odkaz:
https://doaj.org/article/8e9c29a8ef3945a9aee789f4ce40a562
Publikováno v:
Stem Cell Research, Vol 58, Iss , Pp 102599- (2022)
Genetic variants in the GJB2 gene which encodes for the Connexin 26 protein account for ∼ 60% of cases of genetic hearing loss. A novel hiPSC line was generated from an individual with the hearing loss-related variant c.109G > A in GJB2 leading to
Externí odkaz:
https://doaj.org/article/54e38913e929449a855588df7f2f7922
Autor:
Eric Nisenbaum MD, Carly Misztal, Mikhaylo Szczupak MD, Torin Thielhelm, Stefanie Peña MD, Christine Mei MD, Stefania Goncalves MD, Olena Bracho, Ruixuan Ma MS, Michael E. Ivan MD, Jacques Morcos MD, Fred Telischi MD, Xue-Zhong Liu MD, PhD, Cristina Fernandez-Valle PhD, Christine T. Dinh MD
Publikováno v:
OTO Open, Vol 5 (2021)
Objective (1) Characterize the distribution of M1 and M2 macrophages in vestibular schwannomas by hearing status. (2) Develop assays to assess monocyte migration and macrophage polarization in cocultures with vestibular schwannoma cells. Study Design
Externí odkaz:
https://doaj.org/article/98cd671eb85e4952aaf95eab47c96934
Autor:
Aida Nourbakhsh, Nicholas C. Gosstola, Cristina Fernandez-Valle, Derek M. Dykxhoorn, Xue Zhong Liu
Publikováno v:
Stem Cell Research, Vol 55, Iss , Pp 102474- (2021)
The UMi031-A-2 hiPSC line contains a CRISPR-induced homozygous, Neurofibromatosis Type 2 (NF2) mutation (L64P (CTG > CCG)) in the NF2 gene that encodes a merlin tumor suppressor. This line was generated from an unaffected iPSC line using CRISPR techn
Externí odkaz:
https://doaj.org/article/4dec461c3db043138b78ad4f9361b379
Publikováno v:
Stem Cell Research, Vol 54, Iss , Pp 102405- (2021)
Hereditary hearing loss (HL) is the most common sensory disorder with multiple potential modes of inheritance, such as X-linked. Multiple loci have been associated with X-linked HL, including variants in the Small Muscle Protein X-Linked (SMPX) gene
Externí odkaz:
https://doaj.org/article/580786ce50e842eeb00d1b993a9ce113
Autor:
Yinfang Xu, Yan Zhang, Ivan A Lopez, Jacey Hilbers, Anthony J Griswold, Akira Ishiyama, Susan Blanton, Xue Zhong Liu, Yunxia Wang Lundberg
Publikováno v:
PLoS ONE, Vol 16, Iss 5, p e0251386 (2021)
Benign paroxysmal positional vertigo (BPPV) is the most common cause of vertigo in humans, yet the molecular etiology is currently unknown. Evidence suggests that genetic factors may play an important role in some cases of idiopathic BPPV, particular
Externí odkaz:
https://doaj.org/article/38c2bbb8d12249e78cb682cf7cdeecd5
Autor:
Nicholas C. Gosstola, Zaohua Huang, Xiaoying Tong, Aida Nourbakhsh, Zheng-Yi Chen, Derek M. Dykxhoorn, Xue Zhong Liu
Publikováno v:
Stem Cell Research, Vol 49, Iss , Pp 102017- (2020)
UMi028-A-1 hiPSC line contains a CRISPR/Cas9-induced heterozygous, hearing loss-associated variant (V60L (GTA > TTA)) in the Purinergic Receptor P2X2 (P2RX2) gene. This line, derived from an unaffected male iPSC line, has been successfully characteri
Externí odkaz:
https://doaj.org/article/40d0ee6b88e94a7dad955dcb5db7417a