Zobrazeno 1 - 10
of 62
pro vyhledávání: '"Xue Li Guan"'
Publikováno v:
Journal of Mass Spectrometry and Advances in the Clinical Lab, Vol 30, Iss , Pp 25-29 (2023)
Pipettes are essential tools for biomedical and analytical laboratories, analogous to workstations for computer scientists. Variation in pipetting is a known unknown, as it is generally accepted that variations exist, but thus far, there have been li
Externí odkaz:
https://doaj.org/article/e508638421754881aad9ce4a094bb506
Autor:
Anne Kathrin Lösslein, Florens Lohrmann, Lisa Scheuermann, Kourosh Gharun, Jana Neuber, Julia Kolter, Aaron James Forde, Christian Kleimeyer, Ying Yee Poh, Matthias Mack, Antigoni Triantafyllopoulou, Micah D. Dunlap, Shabaana A. Khader, Maximilian Seidl, Alexandra Hölscher, Christoph Hölscher, Xue Li Guan, Anca Dorhoi, Philipp Henneke
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-22 (2021)
Multinucleated giant cells characterize granuloma formation in mycobacterial infections. Here the authors identify monocyte precursors with distinct immunological and metabolic properties as a source of the granuloma multinucleated giant cell compart
Externí odkaz:
https://doaj.org/article/b7de3fe7ad2f4ec7a67aa8fc0ad6eba6
Autor:
Marianne Rocha-Hasler, Gabriel Melo de Oliveira, Aline Nefertiti da Gama, Ludmila Ferreira de Almeida Fiuza, Anna Frieda Fesser, Monica Cal, Romina Rocchetti, Raiza Brandão Peres, Xue Li Guan, Marcel Kaiser, Maria de Nazaré Correia Soeiro, Pascal Mäser
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 11 (2021)
Azoles such as posaconazole (Posa) are highly potent against Trypanosoma cruzi. However, when tested in chronic Chagas disease patients, a high rate of relapse after Posa treatment was observed. It appears that inhibition of T. cruzi cytochrome CYP51
Externí odkaz:
https://doaj.org/article/ee5ab12cf3d84660be77eec921094bc6
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Altered lipid metabolism in macrophages is associated with various important inflammatory conditions. Although lipid metabolism is an important target for therapeutic intervention, the metabolic requirement involved in lipid accumulation during pro-i
Externí odkaz:
https://doaj.org/article/321ec069674b4a23b5d6615ab65f87e2
Autor:
Dorothy Pei Shan Chang, Xue Li Guan
Publikováno v:
Metabolites, Vol 11, Iss 2, p 88 (2021)
Mycobacterium tuberculosis (Mtb), the causative agent of tuberculosis (TB), is a highly successful intracellular pathogen with the ability to withstand harsh conditions and reside long-term within its host. In the dormant and persistent states, the b
Externí odkaz:
https://doaj.org/article/45194f96d3dd412c860f29fd5bd14dda
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
Macrophages are professional phagocytes at the front line of immune defenses against foreign bodies and microbial pathogens. Various bacteria, which are responsible for deadly diseases including tuberculosis and salmonellosis, are capable of hijackin
Externí odkaz:
https://doaj.org/article/cbe57b0378c741fc9296a470a6f5eb7e
Autor:
Lukas Bahati Tanner, Charmaine Chng, Xue Li Guan, Zhengdeng Lei, Steven G. Rozen, Markus R. Wenk
Publikováno v:
Journal of Lipid Research, Vol 55, Iss 7, Pp 1357-1365 (2014)
Influenza virus acquires a host-derived lipid envelope during budding, yet a convergent view on the role of host lipid metabolism during infection is lacking. Using a mass spectrometry-based lipidomics approach, we provide a systems-scale perspective
Externí odkaz:
https://doaj.org/article/6ae0ef190b814cdaad4c9e34b67b9642
Autor:
Elena Lissina, Brian Young, Malene L Urbanus, Xue Li Guan, Jonathan Lowenson, Shawn Hoon, Anastasia Baryshnikova, Isabelle Riezman, Magali Michaut, Howard Riezman, Leah E Cowen, Markus R Wenk, Steven G Clarke, Guri Giaever, Corey Nislow
Publikováno v:
PLoS Genetics, Vol 7, Iss 10, p e1002332 (2011)
Using small molecule probes to understand gene function is an attractive approach that allows functional characterization of genes that are dispensable in standard laboratory conditions and provides insight into the mode of action of these compounds.
Externí odkaz:
https://doaj.org/article/e357c09cbbfb4e029aa124f35878e3ef
Autor:
Guanghou Shui, Xue Li Guan, Pradeep Gopalakrishnan, Yangkui Xue, Joyce Sze Yuin Goh, Hongyuan Yang, Markus R Wenk
Publikováno v:
PLoS ONE, Vol 5, Iss 8, p e11956 (2010)
BackgroundPhosphatidic acid (PA) is a key regulated intermediate and precursor for de novo biosynthesis of all glycerophospholipids. PA can be synthesized through the acylation of lysophosphatidic acid (LPA) by 1-acyl-3-phosphate acyltransferase (als
Externí odkaz:
https://doaj.org/article/2786d2948ab445de925fdc46def295f5
Autor:
Zun Siong Low, Damien Chua, Hong Sheng Cheng, Rachel Tee, Wei Ren Tan, Christopher Ball, Norliza Binte Esmail Sahib, Ser Sue Ng, Jing Qu, Yingzi Liu, Haiyu Hong, Chaonong Cai, Nandini C. L. Rao, Aileen Wee, Mark D. Muthiah, Zoë Bichler, Barbara Mickelson, Jia Qi Lee, Mei Suen Kong, Vanessa S.Y. Tay, Zhuang Yan, Jiapeng Chen, Aik Seng Ng, Yun Sheng Yip, Marcus Ivan Gerard Vos, Debbie Xiu En Lim, Manesh Chittezhath, Jadegoud Yaligar, Sanjay Kumar Verma, Harish Poptani, Xue Li Guan, S. Sendhil Velan, Yusuf Ali, Liang Li, Nguan Soon Tan, Walter Wahli
Adaptive T-cell immune response is essential in conferring protective immunity, a process requiring tight cellular homeostasis regulation. Pathological intrahepatic T-cell landscape has a role in NAFLD propagation; however, its activation remains unk
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3fa97f1db42b4fa5bd0adf6381fb62d1
https://doi.org/10.1101/2023.01.10.523354
https://doi.org/10.1101/2023.01.10.523354