Zobrazeno 1 - 10
of 147
pro vyhledávání: '"Xue‐Qing Zhang"'
Autor:
Xin Bai, Qijing Chen, Fengqiao Li, Yilong Teng, Maoping Tang, Jia Huang, Xiaoyang Xu, Xue-Qing Zhang
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract Lipid nanoparticle-assisted mRNA inhalation therapy necessitates addressing challenges such as resistance to shear force damage, mucus penetration, cellular internalization, rapid lysosomal escape, and target protein expression. Here, we int
Externí odkaz:
https://doaj.org/article/9c11336db0d546d7ae1cf0148ab2721d
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
Abstract Synergistically improving T-cell responsiveness is promising for favorable therapeutic outcomes in immunologically cold tumors, yet current treatments often fail to induce a cascade of cancer-immunity cycle for effective antitumor immunity.
Externí odkaz:
https://doaj.org/article/23f3e82b2ad5467ab638f0de81b6423b
Autor:
Bin Wang, Maoping Tang, Ziwei Yuan, Zhongyu Li, Bin Hu, Xin Bai, Jinxian Chu, Xiaoyang Xu, Xue-Qing Zhang
Publikováno v:
Bioactive Materials, Vol 16, Iss , Pp 232-248 (2022)
Immunotherapy is emerging as a powerful tool for combating many human diseases. However, the application of this life-saving treatment in serious brain diseases, including glioma, is greatly restricted. The major obstacle is the lack of effective tec
Externí odkaz:
https://doaj.org/article/7a41d2d2cab6488eb14ef3ee3939d080
Autor:
Li Xu, Feng-Wei Guo, Xue-Qing Zhang, Tian-Yi Zhou, Chao-Jie Wang, Mei-Yan Wei, Yu-Cheng Gu, Chang-Yun Wang, Chang-Lun Shao
Publikováno v:
Communications Chemistry, Vol 5, Iss 1, Pp 1-8 (2022)
Benzoazepine is a well-known pharmacophore presented in several marketed drugs. Here, the authors report the isolation and total syntheses of asperazepanones A and B from coral-derived Aspergillus candidus, two novel pyrrolinone-fused benzoazepine al
Externí odkaz:
https://doaj.org/article/487b97a1180c4f57a233a28a9da6a78b
Autor:
Hong-Qi Li, Yi-Wei Feng, Yu-Xiang Yang, Xin-Yi Leng, Prof Can Zhang, Shi-Dong Chen, Kevin Kuo, Shu-Yi Huang, Xue-Qing Zhang, Yi Dong, Xiang Han, Xin Cheng, Mei Cui, Lan Tan, Qiang Dong, Jin-Tai Yu
Publikováno v:
Journal of Stroke, Vol 24, Iss 2, Pp 236-244 (2022)
Background and Purpose To explore the causal relationships of elements of the exposome with ischemic stroke and its subtypes at the omics level and to provide evidence for stroke prevention. Methods We conducted a Mendelian randomization study betwee
Externí odkaz:
https://doaj.org/article/f923214fdc8f4da5a0bd338f9045039f
An intrinsically bioactive hydrogel with on-demand drug release behaviors for diabetic wound healing
Publikováno v:
Bioactive Materials, Vol 6, Iss 12, Pp 4592-4606 (2021)
Prolonged, intense inflammation and excessive oxidative stress hinder diabetic wounds from healing normally, leading to disorders downstream including the postponement of re-epithelialization and extracellular matrix (ECM) formation. Herein, we repor
Externí odkaz:
https://doaj.org/article/21ff600dabc84702a20cd193efcea4f3
Autor:
Shu-Yi Huang, Yu-Xiang Yang, Shi-Dong Chen, Hong-Qi Li, Xue-Qing Zhang, Kevin Kuo, Lan Tan, Lei Feng, Qiang Dong, Can Zhang, Jin-Tai Yu
Publikováno v:
BMC Medicine, Vol 19, Iss 1, Pp 1-16 (2021)
Abstract Background Environmental factors are associated with human longevity, but their specificity and causality remain mostly unclear. By integrating the innovative “exposome” concept developed in the field of environmental epidemiology, this
Externí odkaz:
https://doaj.org/article/e55fa56ab012468da08dbf129ad1bd54
Publikováno v:
Bioactive Materials, Vol 3, Iss 4, Pp 401-417 (2018)
Bone self-healing is limited and generally requires external intervention to augment bone repair and regeneration. While traditional methods for repairing bone defects such as autografts, allografts, and xenografts have been widely used, they all hav
Externí odkaz:
https://doaj.org/article/4929cc5f39134fd7917c5ee7ab4b2d5c
Publikováno v:
Molecules, Vol 27, Iss 8, p 2431 (2022)
Nigrosporins B, an anthraquinone derivative obtained from the secondary metabolites of marine fungus Nigrospora oryzae. In this study, we characterized the distinctive anti-cancer potential of Nigrosporins B in vitro and underlying molecular mechanis
Externí odkaz:
https://doaj.org/article/b4f966cddb28411f97cf6f2845292c24
Autor:
Pei-cheng Lin, Xi-jin Lin, Jin-luan Li, Fei-fei Lin, Qing-yang Zhuang, Li-rui Tang, Yun-xia Huang, Xue-qing Zhang, Jun-xin Wu
Publikováno v:
Journal of International Medical Research, Vol 48 (2020)
Purpose To characterize the pattern of post-mastectomy supraclavicular lymph node (LN) metastases in patients with breast cancer (BC) and to provide insights for individualized clinical target volume delineation for radiotherapy. Methods We retrospec
Externí odkaz:
https://doaj.org/article/dabcf874074a49f287b62e5448cbcce5