Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Xucheng Hou"'
Autor:
Diana D. Kang, Xucheng Hou, Leiming Wang, Yonger Xue, Haoyuan Li, Yichen Zhong, Siyu Wang, Binbin Deng, David W. McComb, Yizhou Dong
Publikováno v:
Bioactive Materials, Vol 37, Iss , Pp 86-93 (2024)
Since the approval of the lipid nanoparticles (LNP)-mRNA vaccines against the SARS-CoV-2 virus, there has been an increased interest in the delivery of mRNA through LNPs. However, current LNP formulations contain PEG lipids, which can stimulate the g
Externí odkaz:
https://doaj.org/article/e315aae8bfdd4b60a132b0a4411383a8
Autor:
Yonger Xue, Yuebao Zhang, Yichen Zhong, Shi Du, Xucheng Hou, Wenqing Li, Haoyuan Li, Siyu Wang, Chang Wang, Jingyue Yan, Diana D. Kang, Binbin Deng, David W. McComb, Darrell J. Irvine, Ron Weiss, Yizhou Dong
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract Adipose stem cells (ASCs) have attracted considerable attention as potential therapeutic agents due to their ability to promote tissue regeneration. However, their limited tissue repair capability has posed a challenge in achieving optimal t
Externí odkaz:
https://doaj.org/article/625c5a8ddd304299b6fd4d928fdfa3a5
Autor:
Shi Du, Wenqing Li, Yuebao Zhang, Yonger Xue, Xucheng Hou, Jingyue Yan, Jeffrey Cheng, Binbin Deng, David W. McComb, Jennifer Lin, Hong Zeng, Xiaolin Cheng, Darrell J. Irvine, Ron Weiss, Yizhou Dong
Publikováno v:
Advanced Science, Vol 10, Iss 11, Pp n/a-n/a (2023)
Abstract Male infertility caused by genetic mutations is an important type of infertility. Currently, there is no reliable method in the clinic to address this medical need. The emergence of mRNA therapy provides a possible strategy for restoring mut
Externí odkaz:
https://doaj.org/article/9d73ad80650f478b8530e1d5629c2893
Autor:
Wenqing Li, Xinfu Zhang, Chengxiang Zhang, Jingyue Yan, Xucheng Hou, Shi Du, Chunxi Zeng, Weiyu Zhao, Binbin Deng, David W. McComb, Yuebao Zhang, Diana D. Kang, Junan Li, William E. Carson, Yizhou Dong
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
Antibodies targeting OX40 or CD137, two T cell costimulatory receptors, have been shown to improve antitumor immunity. Here the authors design a phospholipid-derived nanoparticle to deliver OX40 or CD137 mRNA to T cells in vivo, improving efficacy of
Externí odkaz:
https://doaj.org/article/c560ecaa3fe24937b23b46640aec4f30
Autor:
Pengxuan Zhao, Xucheng Hou, Jingyue Yan, Shi Du, Yonger Xue, Wenqing Li, Guangya Xiang, Yizhou Dong
Publikováno v:
Bioactive Materials, Vol 5, Iss 2, Pp 358-363 (2020)
Lipid-like nanoparticles (LLNs) have been extensively explored for messenger RNA (mRNA) delivery in various biomedical applications. However, the long-term storage of these nanoparticles is still a challenge for their clinical translation. In this st
Externí odkaz:
https://doaj.org/article/28560ab836ea444eae9133a67fb4223e
Publikováno v:
View, Vol 2, Iss 4, Pp n/a-n/a (2021)
Abstract The severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) has infected over 100 million people globally due to its high infectivity. After decades of efforts on the studies of nanomaterials, researchers have applied nanomaterials
Externí odkaz:
https://doaj.org/article/04fa652d9ce94c88b5745edcc0e8fa08
Autor:
Shuzhong Zhang, Chandra L. Shrestha, Benjamin L. Wisniewski, Hanh Pham, Xucheng Hou, Wenqing Li, Yizhou Dong, Benjamin T. Kopp
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Macrophage dysfunction is fundamentally related to altered immunity in cystic fibrosis (CF). How genetic deficits in the cystic fibrosis transmembrane conductance regulator (CFTR) lead to these defects remains unknown. Rapid advances in genomic editi
Externí odkaz:
https://doaj.org/article/e67b7af5b37044f380f2de3aa8a546f2
Autor:
Kang, Diana D., Xucheng Hou, Leiming Wang, Yonger Xue, Haoyuan Li, Yichen Zhong, Siyu Wang, Binbin Deng, McComb, David W., Yizhou Dong
Publikováno v:
Bioactive Materials; Jul2024, Vol. 37, p86-93, 8p
Autor:
Siyu Wang, Yuebao Zhang, Yichen Zhong, Yonger Xue, Zhengwei Liu, Chang Wang, Kang, Diana D., Haoyuan Li, Xucheng Hou, Meng Tian, Dinglingge Cao, Leiming Wang, Kaiyuan Guo, Binbin Deng, McComb, David W., Merad, Miriam, Brown, Brian D., Yizhou Dong
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America; 5/28/2024, Vol. 121 Issue 22, p1-10, 40p
Autor:
Yuebao Zhang, Jingyue Yan, Xucheng Hou, Chang Wang, Diana D. Kang, Yonger Xue, Shi Du, Binbin Deng, David W. McComb, Shan-Lu Liu, Yichen Zhong, Yizhou Dong
Publikováno v:
Nano Letters. 23:2593-2600