Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Xuanzuo Chen"'
Autor:
Kanglu Li, Wenbo Yang, Xuanzuo Chen, Yihan Yu, Yiran Liu, Feifei Ni, Yan Xiao, Xiangcheng Qing, Sheng Liu, YuXin He, Baichuan Wang, Li Xu, Zengwu Shao, Lei Zhao, Yizhong Peng, Hui Lin
Publikováno v:
Journal of Nanobiotechnology, Vol 22, Iss 1, Pp 1-24 (2024)
Abstract Lower back pain (LBP) is a common condition closely associated with intervertebral disc degeneration (IDD), causing a significant socioeconomic burden. Inflammatory activation in degenerated discs involves pro-inflammatory cytokines, dysregu
Externí odkaz:
https://doaj.org/article/247757a5d3164ce7a8b506300c0ba353
Autor:
Sheng Liu, Kanglu Li, Yuxin He, Sheng Chen, Wenbo Yang, Xuanzuo Chen, Shiqing Feng, Liming Xiong, Yizhong Peng, Zengwu Shao
Publikováno v:
Advanced Science, Vol 11, Iss 22, Pp n/a-n/a (2024)
Abstract Cellular senescence is a significant contributor to intervertebral disc aging and degeneration. However, the application of senotherapies, such as senomorphics targeting senescence markers and the senescence‐associated secretory phenotype
Externí odkaz:
https://doaj.org/article/0ad176c2b7fb46edb9affe81595cb1dc
Autor:
Shuo Tian, Xuanzuo Chen, Wei Wu, Hui Lin, Xiangcheng Qing, Sheng Liu, BaiChuan Wang, Yan Xiao, Zengwu Shao, Yizhong Peng
Publikováno v:
Experimental and Molecular Medicine, Vol 56, Iss 2, Pp 408-421 (2024)
Abstract Lower back pain (LBP), which is a primary cause of disability, is largely attributed to intervertebral disc degeneration (IDD). Macrophages (MΦs) in degenerated intervertebral discs (IVDs) form a chronic inflammatory microenvironment, but h
Externí odkaz:
https://doaj.org/article/09ec16d90c7443d5b517a2efcc4af14a
Autor:
Yizhong Peng, Xuanzuo Chen, Qimin Zhang, Sheng Liu, Wei Wu, Kanglu Li, Hui Lin, Xiangcheng Qing, Yan Xiao, BaiChuan Wang, Daping Quan, Shiqing Feng, Zilong Rao, Ying Bai, Zengwu Shao
Publikováno v:
Advanced Science, Vol 11, Iss 10, Pp n/a-n/a (2024)
Abstract Exogenous stem cell therapy and endogenous repair has shown great potential in intervertebral disc regeneration. However, limited nutrients and accumulation of lactate largely impair the survival and regenerative capacity of implanted stem c
Externí odkaz:
https://doaj.org/article/ebd970ecac714db7b3ec808f86b8f34a
Autor:
Doudou Jing, Xuanzuo Chen, Zhenhao Zhang, Fengxia Chen, Fuhua Huang, Zhicai Zhang, Wei Wu, Zengwu Shao, Feifei Pu
Publikováno v:
Molecular Medicine, Vol 29, Iss 1, Pp 1-14 (2023)
Abstract Background Osteosarcoma is a malignant bone tumor that usually affects adolescents aged 15–19 y. The DNA damage response (DDR) is significantly enhanced in osteosarcoma, impairing the effect of systemic chemotherapy. Targeting the DDR proc
Externí odkaz:
https://doaj.org/article/ddc202f177e14343b4c9349d1b4467fa
Autor:
Yizhong Peng, Xuanzuo Chen, Sheng Liu, Wei Wu, Hongyang Shu, Shuo Tian, Yan Xiao, Kanglu Li, BaiChuan Wang, Hui Lin, Xiangcheng Qing, Zengwu Shao
Publikováno v:
Small.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::39f90247269be49cb172d31172cd8cfc
https://doi.org/10.1002/smll.202206888
https://doi.org/10.1002/smll.202206888
Autor:
Yizhong Peng, Xuanzuo Chen, Kanglu Li, Yan Xiao, Wei Wu, Hui Lin, Xiangcheng Qing, Shuo Tian, Sheng Liu, Baichuan Wang, Zengwu Shao
Intervertebral disk degeneration (IDD) is the primary pathology responsible for lower back pain. Oxidative stress-induced cell death plays a fundamental role in IDD pathogenesis. Cuproptosis is a recently discovered form of programmed cell death depe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f9108a9a542c632f23362d6562b7fe9e
https://doi.org/10.21203/rs.3.rs-2585336/v1
https://doi.org/10.21203/rs.3.rs-2585336/v1
Autor:
Doudou Jing, Wei Wu, Xuanzuo Chen, Hongwei Xiao, Zhenhao Zhang, Fengxia Chen, Zhicai Zhang, Jianxiang Liu, Zengwu Shao, Feifei Pu
Publikováno v:
Pharmacological Research. 182:106287
Osteosarcoma (OS) is a malignant solid tumor prone to lung metastasis that occurs in adolescents aged 15-19 years. Neoadjuvant chemotherapy and surgical treatment aimed at curing OS have gained limited progress over the last 30 years. Exploring new e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::029614932be70ae1520e14ee6426867d
https://doi.org/10.1016/j.phrs.2022.106287
https://doi.org/10.1016/j.phrs.2022.106287
Autor:
Kexin Deng, Jieyu Wu, Difei Chen, Jianxing He, Lindsey Hamblin, Qihua He, Jiaxuan Xu, Jianrong Zhang, Xinyu Wang, Zhiheng Xu, Shuhan Jiang, Hengrui Liang, Yu Huang, Long Jiang, Jiaqing Zhou, Yaoqi Chen, Yiyin Zhang, Jiaxi He, Wenhua Liang, Shiyan Tang, Xuanzuo Chen
Publikováno v:
BMJ open. 8(9)
ObjectiveUnbiased assessment of tumour response is crucial in randomised controlled trials (RCTs). Blinded independent central review is usually used as a supplemental or monitor to local assessment but is costly. The aim of this study is to investig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84a01510d6d2d65e7b3c4d17c6bee036
https://pubmed.ncbi.nlm.nih.gov/30206071
https://pubmed.ncbi.nlm.nih.gov/30206071
Autor:
Wenjiao Li, Ning Li, Shiyu Dai, Guoqing Hou, Kanglin Guo, Xuanzuo Chen, Changhua Yi, Weiyong Liu, Fei Deng, Yaosong Wu, Xuan Cao
Publikováno v:
FASEB Journal; Sep2019, Vol. 33 Issue 9, p9929-9944, 16p