Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Xuansheng Xiao"'
Autor:
Yang Li, Ke Zhu, Ning Li, Xiaotong Wang, Xuansheng Xiao, Linying Li, Lijuan Li, Ying He, Jinglan Zhang, Jiaoyang Wo, Yanqiu Cui, Haixia Huang, Jianliang Zhang, Wei Wang, Xiaomin Wang, Yan Zheng
Publikováno v:
Alzheimer’s Research & Therapy, Vol 13, Iss 1, Pp 1-14 (2021)
Abstract Background Neuronal hyperactivity related to β-amyloid (Aβ) is considered an early warning sign of Alzheimer disease (AD). Although increasing evidence supports this opinion, the underlying mechanisms are still unknown. Methods Here, we re
Externí odkaz:
https://doaj.org/article/2823388326734ef5921e78f5f3904229
Autor:
Yan Zheng, Xuansheng Xiao, Xiaotong Wang, Ke Zhu, Lijuan Li, Ying He, Jinglan Zhang, Hanning Hu, Yanqiu Cui, Jianliang Zhang
BACE1 is the rate-limiting enzyme for β-amyloid (Aβ) production and therefore is considered a prime drug target for treating Alzheimer’s disease (AD). Nevertheless, the BACE1 inhibitors failed in clinical trials, even exhibiting cognitive worseni
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::90b7988924bffab46729e42fd23e2fd1
https://doi.org/10.21203/rs.3.rs-2017936/v1
https://doi.org/10.21203/rs.3.rs-2017936/v1
Autor:
Ying He, Wei Wang, Linying Li, Xiaotong Wang, Ning Li, Xuansheng Xiao, Jianliang Zhang, Haixia Huang, Yang Li, Ke Zhu, Jinglan Zhang, Yan Zheng, Yanqiu Cui, Xiaomin Wang, Jiaoyang Wo, Lijuan Li
Publikováno v:
Alzheimer's Research & Therapy
Alzheimer’s Research & Therapy, Vol 13, Iss 1, Pp 1-14 (2021)
Alzheimer’s Research & Therapy, Vol 13, Iss 1, Pp 1-14 (2021)
Background Neuronal hyperactivity related to β-amyloid (Aβ) is considered an early warning sign of Alzheimer disease (AD). Although increasing evidence supports this opinion, the underlying mechanisms are still unknown. Methods Here, we recorded wh