Zobrazeno 1 - 10
of 64
pro vyhledávání: '"Xuanrong Sun"'
Publikováno v:
Journal of Nanobiotechnology, Vol 21, Iss 1, Pp 1-22 (2023)
Abstract It is reported that pulmonary fibrosis has become one of the major long-term complications of COVID-19, even in asymptomatic individuals. Currently, despite the best efforts of the global medical community, there are no treatments for COVID-
Externí odkaz:
https://doaj.org/article/df1d5254a086406092f6678bb8876385
Autor:
Dabu Zhu, Qiuqin Zhang, Yifang Chen, Minghua Xie, Jianbo Li, Shen Yao, Ming Li, Zhao Lou, Yue Cai, Xuanrong Sun
Publikováno v:
Drug Delivery, Vol 29, Iss 1, Pp 1398-1408 (2022)
Triptolide (TP), a compound isolated from a Chinese medicinal herb, possesses potent anti-tumor, immunosuppressive, and anti-inflammatory properties, but was clinically limited due to its poor solubility, bioavailability, and toxicity. Considering th
Externí odkaz:
https://doaj.org/article/f001abf024a24eb58c8356b2db05f26c
Autor:
Shanshan Zheng, Yue Cai, Yulu Hong, Yubei Gong, Licheng Gao, Qingyong Li, Le Li, Xuanrong Sun
Publikováno v:
Drug Delivery, Vol 29, Iss 1, Pp 1764-1775 (2022)
After molecule targeted drug, monoclonal antibody and antibody–drug conjugates (ADCs), peptide–drug conjugates (PDCs) have become the next generation targeted anti-tumor drugs due to its properties of low molecule weight, efficient cell penetrati
Externí odkaz:
https://doaj.org/article/415e09736cc741dc9de3ab8598e423bf
Publikováno v:
Journal of Nanobiotechnology, Vol 20, Iss 1, Pp 1-15 (2022)
Abstract Background 7-p-trifluoromethylphenyl-FL118 (FLQY2) is a camptothecin analog with excellent antitumor efficacy against various solid tumors. However, its poor solubility and low bioavailability limited the development of the drug. Polyvinyl c
Externí odkaz:
https://doaj.org/article/5cbe76cd935d437988fd20ff48ba5c6d
Autor:
Yan Chen, Pengfu Liu, Jiequn Wu, Wanqing Yan, Saixue Xie, Xuanrong Sun, Bang-Ce Ye, Xiaohe Chu
Publikováno v:
Journal of Nanobiotechnology, Vol 20, Iss 1, Pp 1-15 (2022)
Abstract Background The disease caused by plant pathogenic bacteria in the production, transportation, and storage of many crops has brought huge losses to agricultural production. N-acylhomoserine lactonases (AHLases) can quench quorum-sensing (QS)
Externí odkaz:
https://doaj.org/article/2aecdbf7c282454f9e3e1696da64b83f
Autor:
Zhuomin Xu, Shanshan Zheng, Xin Gao, Yulu Hong, Yue Cai, Qiuqin Zhang, Jiani Xiang, Dehui Xie, Fuxing Song, Huawei Zhang, Hong Wang, Xuanrong Sun
Publikováno v:
Journal of Nanobiotechnology, Vol 19, Iss 1, Pp 1-11 (2021)
Abstract Background Chrysomycin A (CA) has been reported as numerous excellent biological activities, such as antineoplastic and antibacterial. Though, poor solubility of CA limited its application in medical field. Due to good amphiphilicity and pot
Externí odkaz:
https://doaj.org/article/021315b96f4b4537b8d040fdade6d94b
Autor:
Haohua Liu, Yue Cai, Yuteng Chu, Xiaojie Yu, Fuhang Song, Hong Wang, Huawei Zhang, Xuanrong Sun
Publikováno v:
Molecules, Vol 27, Iss 14, p 4613 (2022)
Chrysomycin A, a compound derived from marine microorganisms, proved to have a specific great in vitro inhibitory effect on methicillin-resistant Staphylococcus aureus (MRSA). It exhibits high safety for the skin, as well as a better therapeutic effe
Externí odkaz:
https://doaj.org/article/31b6100244af43aebe4a251c87384fac
Autor:
Yi Wang, Xiangli Zhang, Wenya Zhuang, Yanlei Yu, Xuanrong Sun, Hong Wang, Fengzhi Li, Qingyong Li
Publikováno v:
Molecules, Vol 27, Iss 12, p 3669 (2022)
Irinotecan and Topotecan are two Camptothecin derivatives (CPTs) whose resistance is associated with the high expression of breast cancer resistance protein (BCRP) and P-glycoprotein (P-gp). To reverse this resistance, two novel CPTs, FL77-28 (7-(3-F
Externí odkaz:
https://doaj.org/article/04a149ba86554f40be36b934c3fbbc2f
Publikováno v:
Molecules, Vol 24, Iss 8, p 1477 (2019)
We developed a tumor-targeted contrast agent based on linear polylysine (PLL) by conjugating a small molecular imaging agent, fluorescent molecule and targeting agent amino phenylboronic acid onto the amino groups of polylysine, which can specificall
Externí odkaz:
https://doaj.org/article/d857a05165dc4e7db96a968bde94730e
Publikováno v:
Molecules, Vol 24, Iss 3, p 624 (2019)
Pyrano[2,3-c]pyrazole derivatives have been reported as exerting various biological activities. One compound with potential anti-tumor activity was screened out by MTT assay from series of dihydropyrazopyrazole derivatives we had synthesized before u
Externí odkaz:
https://doaj.org/article/6a6b5173aa0a4b8681c5bb85cc52994b