Zobrazeno 1 - 10
of 56
pro vyhledávání: '"Xuanming, Yang"'
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract RORγt+ group 3 innate lymphoid cells (ILC3s) are essential for intestinal homeostasis. Dysregulation of ILC3s has been found in the gut of patients with inflammatory bowel disease and colorectal cancer, yet the specific mechanisms still req
Externí odkaz:
https://doaj.org/article/d5f9a747d94a494e9e4ce68766c95dc0
Autor:
Fanlin Li, Wei Xu, Xiaoqing Zhang, Wanting Wang, Shan Su, Ping Han, Haiyong Wang, Yanqin Xu, Min Li, Lilv Fan, Huihui Zhang, Qiang Dai, Hao Lin, Xinyue Qi, Jie Liang, Xin Wang, Shibo Jiang, Youhua Xie, Lu Lu, Xuanming Yang
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-11 (2023)
Abstract Neutralizing antibodies exert a potent inhibitory effect on viral entry; however, they are less effective in therapeutic models than in prophylactic models, presumably because of their limited efficacy in eliminating virus-producing cells vi
Externí odkaz:
https://doaj.org/article/b7a498ffd1334d3186cafe0e8610e70d
Publikováno v:
Symmetry, Vol 16, Iss 3, p 328 (2024)
Voltage sags resulting from symmetrical or asymmetrical faults pose a significant threat to power quality. In response to this challenge, a voltage sag loss assessment method based on a two-stage Taguchi quality perspective approach is proposed to ad
Externí odkaz:
https://doaj.org/article/e8e2bd1b6bb3451d92276ef2c3dce542
Autor:
Fanlin Li, Huihui Zhang, Wanting Wang, Puyuan Yang, Yue Huang, Junshi Zhang, Yaping Yan, Yuan Wang, Xizhong Ding, Jie Liang, Xinyue Qi, Min Li, Ping Han, Xiaoqing Zhang, Xin Wang, Jiang Cao, Yang-Xin Fu, Xuanming Yang
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)
Healthy T cells are polyclonal, while malignant T cells are developing via clonal expansion. Here authors show that T cell tumours could be eradicated by chimeric antigen receptor T cells targeting the T cell receptor (TCR) β-chain that is specific
Externí odkaz:
https://doaj.org/article/02c488a10011477f8b02989ecac19cbe
Autor:
Xiaoqing Zhang, Ping Han, Haiyong Wang, Yanqin Xu, Fanlin Li, Min Li, Lilv Fan, Huihui Zhang, Qiang Dai, Hao Lin, Xinyue Qi, Jie Liang, Xin Wang, Xuanming Yang
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 21, Iss , Pp 754-764 (2021)
The emergence of the novel human severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) has led to the pandemic of coronavirus disease 2019 (COVID-19), which has markedly affected global health and the economy. Both uncontrolled viral replicati
Externí odkaz:
https://doaj.org/article/1e369a27ea6041b39a76e280dea414a4
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Externí odkaz:
https://doaj.org/article/546a1ed736204e92ba8bfd1f6073d8c0
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
Agonistic 4-1BB antibodies developed for cancer immunotherapy have suffered from either hepatotoxicity or insufficient anti-cancer activity. Here the authors determine the contribution of FcγR binding and agonistic strength to these outcomes, and en
Externí odkaz:
https://doaj.org/article/00f1cb7bc64c4223a182e521b81631ef
Autor:
Qiang Dai, Ping Han, Xinyue Qi, Fanlin Li, Min Li, Lilv Fan, Huihui Zhang, Xiaoqing Zhang, Xuanming Yang
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
While chimeric antigen receptor-modified T (CAR-T) cells have shown great success for the treatment of B cell leukemia, their efficacy appears to be compromised in B cell derived lymphoma and solid tumors. Optimization of the CAR design to improve pe
Externí odkaz:
https://doaj.org/article/db9d350a6df9418a9d77903e60fcba47
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Somatic gene mutations play a critical role in immune evasion by tumors. However, there is limited information on genes that confer immunotherapy resistance in melanoma. To answer this question, we established a whole-genome knockout B16/ovalbumin ce
Externí odkaz:
https://doaj.org/article/f81623bf3ad64984bbfed8e8d99fc8b9
PDF file - 20K, The majority of CD11b+ cells were F4/80+ in the prostate of TRAMP mice
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99b4d19e472e5e65fe1899cd5acabb87
https://doi.org/10.1158/0008-5472.22398755
https://doi.org/10.1158/0008-5472.22398755
