Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Xuandai Nguyen"'
Autor:
Dani S. Zander, Gary A. Visner, Y.i-Hao Weng, Guang Yang, Xuandai Nguyen, Fuhua Lu, Phyllis A. Dennery
Publikováno v:
Free Radical Biology and Medicine. 34:124-133
In many models, a protective role for heme oxygenase-1 (HO-1), the rate-limiting enzyme in heme degradation, has been demonstrated. Also, HO-1 null mice (KO) are more susceptible to inflammation and hypoxia and transplant rejection. Nonetheless, thei
Autor:
Attallah Kappas, Phyllis A. Dennery, Michal L. Schwartzman, Abdelmonem ElHosseiny, Fan Zhang, Alberto Nasjletti, Xuandai Nguyen, Hatem E. Sabaawy, Nader G. Abraham
Publikováno v:
Hypertension. 38:210-215
Heme oxygenase (HO) catalyzes the conversion of heme to biliverdin, with release of free iron and carbon monoxide. Both heme and carbon monoxide have been implicated in the regulation of vascular tone. A retroviral vector containing human HO-1 cDNA (
Publikováno v:
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 276:R1691-R1700
20-Hydroxyeicosatetraenoic acid (HETE), the cytochrome P-450 (CYP) 4A ω-hydroxylation product of arachidonic acid, has potent biological effects on renal tubular and vascular functions and on the control of arterial pressure. We have expressed high
Autor:
Barbara A. Zand, Hui Guan, Mong Heng Wang, Michal Laniado-Schwartzman, Xuandai Nguyen, Alberto Nasjletti
Publikováno v:
American Journal of Physiology-Renal Physiology. 276:F246-F253
20-Hydroxyeicosatetraenoic acids (20-HETE), a biologically active cytochrome P-450 (CYP) metabolite of arachidonic acid in the rat kidney, can be catalyzed by CYP4A isoforms including CYP4A1, CYP4A2, and CYP4A3. To determine the contribution of CYP4A
Autor:
Flora Kalish, Ronald J. Wong, Hui Zhao, Xuandai Nguyen, Christopher H. Contag, Hendrik J. Vreman, Masami Mizobuchi, David K. Stevenson
Publikováno v:
Pediatric research. 60(5)
Heme oxygenase (HO), the rate-limiting enzyme in heme degradation, plays a role in neonatal jaundice. Understanding the regulation of the developmental expression patterns of the two HO isozymes, HO-1 and HO-2, is essential for targeting HO to contro
Autor:
David A. Stevenson, Nader G. Abraham, Phyllis A. Dennery, Xuandai Nguyen, Doron Kreiser, Daniel S. Seidman, Shou Quan, Ronald J. Wong
Publikováno v:
Laboratory investigation; a journal of technical methods and pathology. 82(6)
Intrauterine growth restriction is associated with increased perinatal morbidity and mortality as well as with lifelong cardiovascular and metabolic complications. Deficiency of heme oxygenase 1 (HO-1) is associated with growth restriction in mice an
Autor:
David K. Stevenson, Guang Yang, Phyllis A. Dennery, Judy I. Ou, Xuandai Nguyen, Prasad Rekulapelli
Publikováno v:
Blood. 97(5)
Zinc protoporphyrin (ZnPP), a naturally occurring molecule, is increased in iron deficiency and lead intoxication. ZnPP can also induce heme oxygenase (HO-1), the enzyme it competitively inhibits. In cultured cells (HA-1), ZnPP was the strongest HO-1
Autor:
Kreiser, Doron, Xuandai Nguyen, Ron Wong, Seidman, Daniel, Stevenson, David, Shou Quan, Abraham, Nader, Dennery, Phyllis A.
Publikováno v:
Laboratory Investigation (00236837); Jun2002, Vol. 82 Issue 6, p687-692, 6p