Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Xuan-Ping Pang"'
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 82:2633-2638
In normal thyroid cells, the TSH-adenylate cyclase system plays a pivotal role in controlling growth and differentiation. However, the role of this system in the growth of thyroid carcinoma is not well understood. To investigate this subject, we have
Publikováno v:
Thyroid. 6:313-317
Tumor necrosis factor-alpha (TNF-alpha) and interferon-gamma (IFN-gamma) inhibit the growth of the human papillary thyroid carcinoma (PTC) cell line, NP. Exposure of NP cells to TNF-alpha resulted in the development of several PTC cell lines (R30, R4
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 78:862-866
hCG is known to have thyroid-stimulating activity and may cause hyperthyroidism in patients with trophoblastic diseases. hCG occurs in normal and molar pregnancy with breaks or nicks in the alpha- or beta-subunit peptide linkage and with substantial
Autor:
A. E. Pekary, L. Berg, L. A. Cole, Jerome M. Hershman, A. Kardana, M. Yoshimura, Xuan-Ping Pang
Publikováno v:
European Journal of Endocrinology. 130:92-96
Yoshimura M, Pekary AE, Pang X-P, Berg L, Cole LA, Kardana A, Hershman JM. Effect of peptide nicking in the human chorionic gonadotropin β-subunit on stimulation of recombinant human thyroid-stimulating hormone receptors. Eur J Endocrinol 1994;130:9
Publikováno v:
Endocrinology. 131:45-50
Recent studies have shown that transforming growth factor-beta (TGF beta) alters DNA synthesis and iodide metabolism in human, porcine, and rat thyroid cells. In the present work we studied the mechanism of TGF beta action in FRTL-5 rat thyroid cells
Publikováno v:
Journal of Biological Chemistry. 267:12826-12830
Human papillary thyroid carcinoma (PTC) has a relatively benign prognosis despite a high frequency of lymphatic metastasis. This suggests that local anticancer factors, generated in lymph nodes, control PTC progression. The cytokine, tumor necrosis f
Publikováno v:
Acta Endocrinologica. 123:203-210
Previous work showed that treatment of rats with tumour necrosis factor-α produced a model of nonthyroid illness in which there was reduction of circulating thyroid hormones and TSH, reduced thyroid response to TSH, and reduced thyroid iodide uptake
Autor:
Vicky A. Cameron, Richard P. Michael, Rod J.E. Horton, Robert Stephens, Theodor H. Lippert, Pei-Juan Shen, Paulette Collins, Iain J. Clarke, J. T. Cummins, Eugene Pekary, Wan-hua Amy Yu, Jean-Didier Vincent, Rosaria Melis, Carlos Dieguez, Julie A. Chowen, Pascal Legendre, Charles B. Nemeroff, Donald K. Clifton, Jesús Argente, Jin Zhang, Jorge Bartolome, Bartolome Burguera, Christian Bartsch, Xuan-Ping Pang, Linda Vician, Howard D. Rees, Vierka Smith, Fukuko Kimura, Luis Benitez, Noeline B. Marsh, Hella Bartsch, Roberto Stancampiano, Antonio Argiolas, Jean-Marc Israel, Frank D. Sabatino, Robert W. Bonsall, Andrea Vaccari, Federico Mallo, Jerome M. Hershman, Jiang-Yuan Li, Tatsuo Akema, Lugi Gessa, Pierre-Marie Lledo, Robert A. Steiner, David Wynick, Derek Gupta, Saul M. Schanberg, M. J. Owens, Atsuhiko Chiba, Franco Sánchez-Franco, Eric A. Espiner, Marie Simard, I. C. H. Smith, John K. McDonald, Joseph J. DiStefano, Clara V. Alvarez, Stephen R. Bloom
Publikováno v:
Neuroendocrinology. 52:634-636
Autor:
Jerome M. Hershman, Xuan-Ping Pang
Publikováno v:
Thyroid : official journal of the American Thyroid Association. 8(11)
We have shown that both tumor necrosis factor-alpha (TNF-alpha) and transforming growth factor-beta1 (TGF-beta1) inhibit the growth of the human papillary thyroid carcinoma (PTC) cell line, NPA. In previous work, we developed NPA cells that were resi
Publikováno v:
The Journal of clinical endocrinology and metabolism. 80(5)
To test the hypothesis that interferon-gamma (IFN gamma) and interleukin-1 beta (IL-1 beta) possess antitumor activity on human papillary thyroid carcinoma cells, we studied the in vitro effects of IFN gamma and IL-1 beta on the proliferation and inv