Zobrazeno 1 - 10
of 1 019
pro vyhledávání: '"Xuan QIN"'
Autor:
Weifeng Zhang, Xuan Qin, Gaocai Li, Xingyu Zhou, Hongyang Li, Di Wu, Yu Song, Kangcheng Zhao, Kun Wang, Xiaobo Feng, Lei Tan, Bingjin Wang, Xuhui Sun, Zhen Wen, Cao Yang
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract Excessive exercise is an etiological factor of intervertebral disc degeneration (IVDD). Engineered extracellular vesicles (EVs) exhibit excellent therapeutic potential for disease-modifying treatments. Herein, we fabricate an exercise self-p
Externí odkaz:
https://doaj.org/article/ede40b3f76a640919b8aa4cbdd99f6a3
Autor:
Yang Han, Hongbing Zheng, Yingxue Liu, Min Wang, Jiadong Wang, Qing Xie, Shuailin Jing, Xuan Qin, Liqun Zhang
Publikováno v:
ACS Omega, Vol 9, Iss 12, Pp 13897-13905 (2024)
Externí odkaz:
https://doaj.org/article/1d61d1020d5f4f86ac6e92cf11f69577
Publikováno v:
Biomolecules, Vol 14, Iss 9, p 1125 (2024)
Cytochrome P450 enzymes (P450s) play a critical role in drug metabolism, with the CYP3A subfamily being responsible for the biotransformation of over 50% of marked drugs. While CYP3A enzymes are known for their extensive catalytic versatility, one in
Externí odkaz:
https://doaj.org/article/75d7e92570dc4790b993f72eebdc0df1
Autor:
Ravikumar Jimmidi, Srinivas Chamakuri, Shuo Lu, Melek Nihan Ucisik, Peng-Jen Chen, Kurt M. Bohren, Seyed Arad Moghadasi, Leroy Versteeg, Christina Nnabuife, Jian-Yuan Li, Xuan Qin, Ying-Chu Chen, John C. Faver, Pranavanand Nyshadham, Kiran L. Sharma, Banumathi Sankaran, Allison Judge, Zhifeng Yu, Feng Li, Jeroen Pollet, Reuben S. Harris, Martin M. Matzuk, Timothy Palzkill, Damian W. Young
Publikováno v:
Communications Chemistry, Vol 6, Iss 1, Pp 1-10 (2023)
Abstract The development of SARS-CoV-2 main protease (Mpro) inhibitors for the treatment of COVID-19 has mostly benefitted from X-ray structures and preexisting knowledge of inhibitors; however, an efficient method to generate Mpro inhibitors, which
Externí odkaz:
https://doaj.org/article/aab44f4c21884a5ab19d7b954a87359d
Publikováno v:
BMJ Open, Vol 14, Iss 1 (2024)
Introduction Etrolizumab is a gut-targeted, anti-β7 integrin, monoclonal antibody. Recently, data from phase 2 and 3 trials presented different results in patients with moderately to severely active ulcerative colitis. The aim of this study is to su
Externí odkaz:
https://doaj.org/article/1f6c26c67c5e467a9924d1456ea5be82
Publikováno v:
Cogent Economics & Finance, Vol 11, Iss 1 (2023)
AbstractWe built an early warning model for financial risk using a back propagation neural network. To this end, the financial data of 136 listed Internet financial companies in the People’s Republic of China were selected, spanning from 2010–201
Externí odkaz:
https://doaj.org/article/ac56c25f16834461b4538ebf6045ba07
Autor:
Tong Li, Jie Shi, Longlong Wang, Xuan Qin, Rui Zhou, Ming Dong, Fan Ren, Xin Li, Zihe Zhang, Yanan Chen, Yanhua Liu, Yongjun Piao, Yi Shi, Song Xu, Jun Chen, Jia Li
Publikováno v:
MedComm, Vol 4, Iss 5, Pp n/a-n/a (2023)
Abstract Immune checkpoint blockades are the most promising therapy in lung adenocarcinoma (LUAD). However, the response rate remains limited, underscoring the urgent need for effective sensitizers. Interleukin 4 induced 1 (IL4I1) is reported to have
Externí odkaz:
https://doaj.org/article/b3755f85cbfa4aa888eaedab431fe7a6
Autor:
Yilin Hu, Wei Li, Jianxun Zhu, Shu-Meng Hao, Xuan Qin, Li-Zhen Fan, Liqun Zhang, Weidong Zhou
Publikováno v:
Next Energy, Vol 1, Iss 3, Pp 100042- (2023)
Solid-state lithium batteries are promising candidates for improving battery safety and boosting energy density. However, the application of both typical solid-state electrolytes, inorganic ceramic/glass and organic polymer electrolytes, are facing t
Externí odkaz:
https://doaj.org/article/2876f8a1afd442d1b09d8595b7a28e12
Autor:
David J. Matye, Xuan Qin, Mohammad Nazmul Hasan, Lijie Gu, Yung Dai Clayton, Feng Li, Tiangang Li
Publikováno v:
Liver Research, Vol 6, Iss 4, Pp 276-283 (2022)
Background and aims: Several bile acids-based monotherapies have been developed for non-alcoholic steatohepatitis (NASH) treatment but clinical trial findings suggest that they do not satisfactorily improve NASH and liver fibrosis in many patients. R
Externí odkaz:
https://doaj.org/article/beea8ecf722143c8bf8cb6f59073c383
Autor:
Doris Yang, Donna E. Hansel, Marcel E. Curlin, John M. Townes, William B. Messer, Guang Fan, Xuan Qin
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract SARS-CoV-2 is notable for its extremely high level of viral replication in respiratory epithelial cells, relative to other cell types. This may partially explain the high transmissibility and rapid global dissemination observed during the CO
Externí odkaz:
https://doaj.org/article/8d9be3a0331b43208d227a1b05fdc584