Zobrazeno 1 - 10
of 758
pro vyhledávání: '"XuSheng Wang"'
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-9 (2024)
Abstract Deconvolution is an efficient approach for detecting cell-type-specific (cs) transcriptomic signals without cellular segmentation. However, this type of methods may require a reference profile from the same molecular source and tissue type.
Externí odkaz:
https://doaj.org/article/dc02b5c30fe0466fbb9c9e8a3fad1795
Autor:
Miaomiao Li, Xusheng Wang, Rosalind Kieran, Zheng Wei Sun, Yubin Gong, Hongzhao Lei, Bin Sun, Li Xiao, Yanlin Wang, Song Wang, Zhiyu Li, Luying Wang, Renrong Lv, Feng Xue, Jianfeng Ge, Changxian Dong, Ran Huo
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
BackgroundKaposiform hemangioendothelioma (KHE) is a rare vascular tumor with a high risk of mortality. Few studies with large samples of KHE have been reported. KHE may develop into the Kasabach–Merritt phenomenon (KMP), which is characterized by
Externí odkaz:
https://doaj.org/article/20a4b113b67147c7a98d51d09e2cf9bd
Autor:
Gisele Nishiguchi, Lauren G. Mascibroda, Sarah M. Young, Elizabeth A. Caine, Sherif Abdelhamed, Jeffrey J. Kooijman, Darcie J. Miller, Sourav Das, Kevin McGowan, Anand Mayasundari, Zhe Shi, Juan M. Barajas, Ryan Hiltenbrand, Anup Aggarwal, Yunchao Chang, Vibhor Mishra, Shilpa Narina, Melvin Thomas, Allister J. Loughran, Ravi Kalathur, Kaiwen Yu, Suiping Zhou, Xusheng Wang, Anthony A. High, Junmin Peng, Shondra M. Pruett-Miller, Danette L. Daniels, Marjeta Urh, Anang A. Shelat, Charles G. Mullighan, Kristin M. Riching, Guido J. R. Zaman, Marcus Fischer, Jeffery M. Klco, Zoran Rankovic
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Molecular-glue degraders are small molecules that induce a specific interaction between an E3 ligase and a target protein, resulting in the target proteolysis. The discovery of molecular glue degraders currently relies mostly on screening ap
Externí odkaz:
https://doaj.org/article/93a742dfa7284effac1e877a18d0d84e
Publikováno v:
Shuiwen dizhi gongcheng dizhi, Vol 51, Iss 1, Pp 1-11 (2024)
The analytical solution of distributed water table in an unconfined aquifer between streams has been obtained in classic groundwater hydraulics based on Dupuit’s assumption, and it is frequently used in engineering practice. However, the applicabil
Externí odkaz:
https://doaj.org/article/351602c1f11a455c94489a58efc5e33a
Autor:
Xinxin Li, Runlu Shi, Lingchen Yan, Weiwei Chu, Ruishuang Sun, Binkai Zheng, Shuai Wang, Hui Tan, Xusheng Wang, Ying Gao
Publikováno v:
Natural Products and Bioprospecting, Vol 13, Iss 1, Pp 1-16 (2023)
Abstract Norepinephrine (NA), a stress hormone, can accelerate hair graying by binding to β2 adrenergic receptors (β2AR) on melanocyte stem cells (McSCs). From this, NA-β2AR axis could be a potential target for preventing the stress effect. Howeve
Externí odkaz:
https://doaj.org/article/cd374ed6f1fc4c30a5a8c09ca2fcfb17
Autor:
Liam C. Hunt, Vishwajeeth Pagala, Anna Stephan, Boer Xie, Kiran Kodali, Kanisha Kavdia, Yong-Dong Wang, Abbas Shirinifard, Michelle Curley, Flavia A. Graca, Yingxue Fu, Suresh Poudel, Yuxin Li, Xusheng Wang, Haiyan Tan, Junmin Peng, Fabio Demontis
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-22 (2023)
Abstract Ubiquitination is a post-translational modification initiated by the E1 enzyme UBA1, which transfers ubiquitin to ~35 E2 ubiquitin-conjugating enzymes. While UBA1 loss is cell lethal, it remains unknown how partial reduction in UBA1 activity
Externí odkaz:
https://doaj.org/article/ecc3809ff4864ac888167d9faaecd3c0
Publikováno v:
Biosensors, Vol 14, Iss 9, p 420 (2024)
Flexible electrochemical sensors can adhere to any bendable surface with conformal contact, enabling continuous data monitoring without compromising the surface’s dynamics. Among various materials that have been explored for flexible electronics, m
Externí odkaz:
https://doaj.org/article/1de80ccbeefe40bd931cc28d04905fd0
Publikováno v:
Environment International, Vol 186, Iss , Pp 108638- (2024)
Microplastics (MPs) are pervasive pollutants in the natural environment and contribute to increased levels of illness in both animals and humans. However, the specific impacts of MPs on skin damage and alopecia are not yet well understood. In this st
Externí odkaz:
https://doaj.org/article/fdba7ce177c94a07bf6ccc524520ecde
Publikováno v:
Frontiers in Energy Research, Vol 12 (2024)
Traditional horizontal-axis wind turbines (HAWTs) have limited efficiency in low-wind speed regions. In this paper, an integrated energy system (IES) incorporating vertical-axis wind turbines (VAWTs) is proposed; this IES is located in an oilfield ma
Externí odkaz:
https://doaj.org/article/314fcee74c34480eb921c2ac0e09f98f
Publikováno v:
地质科技通报, Vol 42, Iss 4, Pp 15-26 (2023)
Objective The Dupuit model of well flow is a classical steady-state well flow model for a homogeneous unconfined aquifer in a round island. However, it does not consider the widely existing infiltration recharge from precipitation, and is also inappl
Externí odkaz:
https://doaj.org/article/4b51ca3a7cb44642998b7dbdc283f00e