Zobrazeno 1 - 10
of 32
pro vyhledávání: '"XuMing Song"'
Autor:
Rutao Li, Yijian Zhang, Anpeng Wang, Yipeng Feng, Te Zhang, Hui Wang, Yuzhong Chen, Xinnian Yu, Xuming Song, HanLin Ding, Lin Xu, Gaochao Dong, Feng Jiang
Publikováno v:
Cell Death Discovery, Vol 10, Iss 1, Pp 1-12 (2024)
Abstract Previous studies revealed that MIR155HG possessed an oncogenic role in many types of tumors including lung adenocarcinoma (LUAD), along with higher expression in tumors. However, in our study, we observed a positive correlation between MIR15
Externí odkaz:
https://doaj.org/article/d03a21b5430b42dfb21194f634bd9759
Autor:
Hui Wang, Qianfan Hu, Yuzhong Chen, Xing Huang, Yipeng Feng, Yuanjian Shi, Rutao Li, Xuewen Yin, Xuming Song, Yingkuan Liang, Te Zhang, Lin Xu, Gaochao Dong, Feng Jiang
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract Osimertinib (Osi) is a widely used epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKI). However, the emergence of resistance is inevitable, partly due to the gradual evolution of adaptive resistant cells during initial trea
Externí odkaz:
https://doaj.org/article/741ef9fc133f4076aa3904c1e5479186
Autor:
Yipeng Feng, Te Zhang, Zeyu Zhang, Yingkuang Liang, Hui Wang, Yuzhong Chen, Xinnian Yu, Xuming Song, Qixing Mao, Wenjie Xia, Bing Chen, Lin Xu, Gaochao Dong, Feng Jiang
Publikováno v:
Cell Death and Disease, Vol 14, Iss 8, Pp 1-13 (2023)
Abstract Super-enhancers (SEs) are regulatory element clusters related to cell identity and disease. While the studies illustrating the function of SE-associated long noncoding RNAs (lncRNAs) in lung adenocarcinoma (LUAD) remains few. In our research
Externí odkaz:
https://doaj.org/article/c1e0f728311e444886b1a4fdfe75ee2c
Autor:
Yuzhong Chen, Yuanjian Shi, Hanlin Ding, Yipeng Feng, Te Zhang, Yingkuan Liang, Hui Wang, Xuming Song, Bing Chen, Wenjie Xia, Qixing Mao, Bo Shen, Lin Xu, Gaochao Dong, Feng Jiang
Publikováno v:
Therapeutic Advances in Medical Oncology, Vol 15 (2023)
Background: The profile of immune-related adverse events (irAEs) due to programmed death-1 (PD-1) inhibitors-based combination therapy in advanced non-small cell lung cancer (NSCLC) and its relationship with survival have not been fully described. Ob
Externí odkaz:
https://doaj.org/article/b90ff56eed5145c3837a6ac38b018c7b
Autor:
Xuming Song, Te Zhang, Hanlin Ding, Yipeng Feng, Wenmin Yang, Xuewen Yin, Bing Chen, Yingkuan Liang, Qixing Mao, Wenjie Xia, Guiping Yu, Lin Xu, Gaochao Dong, Feng Jiang
Publikováno v:
Oncogenesis, Vol 11, Iss 1, Pp 1-12 (2022)
Abstract Lung adenocarcinoma (LUAD) exhibits high heterogeneity and is well known for its high genetic variation. Recently, the understanding of non-genetic variation provides a new perspective to study the heterogeneity of LUAD. Little is known abou
Externí odkaz:
https://doaj.org/article/78e39827861d4848a076b7b1015e207a
Autor:
Te Zhang, Wenjie Xia, Xuming Song, Qixing Mao, Xing Huang, Bing Chen, Yingkuan Liang, Hui Wang, Yuzhong Chen, Xinnian Yu, Zeyu Zhang, Wenmin Yang, Lin Xu, Gaochao Dong, Feng Jiang
Publikováno v:
Journal of Hematology & Oncology, Vol 15, Iss 1, Pp 1-21 (2022)
Abstract Background Lung adenocarcinoma (LUAD) is the leading cause of death worldwide. However, the roles of long noncoding RNAs (lncRNAs) hijacked by super-enhancers (SEs), vital regulatory elements of the epigenome, remain elusive in the progressi
Externí odkaz:
https://doaj.org/article/007d1858a7974dd590cf802d888658b4
Publikováno v:
PeerJ, Vol 11, p e15672 (2023)
A growing body of evidence suggests that anesthetics impact the outcome of patients with cancer after surgical intervention. However, the optimal dose and underlying mechanisms of co-administered anesthetics in lung tumor therapy have been poorly stu
Externí odkaz:
https://doaj.org/article/c223480c66f84d4cae4b1a157ea4982b
Autor:
Feng Jiang, Qixing Mao, Lin Xu, Bing Chen, Xuewen Yin, Rutao Li, Xuming Song, Te Zhang, Yingkuan Liang, Yu-Zhong Chen, Xinnian Yu, Wenjie Xia, Gaochao Dong
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss 6 (2023)
Background It has been reported that smoking history as a predictor of immunotherapy efficacy in patients with advanced lung cancer, however, the underlying mechanisms of this phenomenon remain largely unknown.Methods The patients with lung adenocarc
Externí odkaz:
https://doaj.org/article/9829fa03fbd649fe80f7c1d76db654d8
Autor:
Yi Zhang, Xuewen Yin, Qi Wang, Xuming Song, Wenjie Xia, Qixing Mao, Bing Chen, Yingkuan Liang, Te Zhang, Lin Xu, Feng Jiang, Xinyu Xu, Gaochao Dong
Publikováno v:
BMC Cancer, Vol 21, Iss 1, Pp 1-12 (2021)
Abstract Background This study aimed to develop a reliable immune signature based on B-cell proportion to predict the prognosis and benefit of immunotherapy in LUAD. Methods The proportion of immune cells in the TCGA-LUAD dataset was estimated using
Externí odkaz:
https://doaj.org/article/d104cbfeffb74a60846df5e6359f23d0
Autor:
Yingkuan Liang, Hui Wang, Bing Chen, Qixing Mao, Wenjie Xia, Te Zhang, Xuming Song, Zeyu Zhang, Lin Xu, Gaochao Dong, Feng Jiang
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 23, Iss , Pp 355-368 (2021)
Aberrant expression of circular RNAs (circRNAs) is involved in cancer progression through interaction with RNA-binding proteins (RBPs). Herein, we screened circRNA expression of A549 cells in circBase and the crosslinking immunoprecipitation (CLIP) d
Externí odkaz:
https://doaj.org/article/6e8cb205df094802a73cb782dadf2a08