Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Xu-shun Jiang"'
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Dyslipidemia is the most prevalent independent risk factor for patients with chronic kidney disease (CKD). Lipid-induced NLRP3 inflammasome activation in kidney-resident cells exacerbates renal injury by causing sterile inflammation. Nuclear factor e
Externí odkaz:
https://doaj.org/article/fb1aca208c624d1d9d1bdfbddf16780e
Autor:
Xu-shun Jiang, Meng-yao Cai, Xun-jia Li, Qing Zhong, Man-li Li, Yun-feng Xia, Qing Shen, Xiao-gang Du, Hua Gan
Publikováno v:
Frontiers in Medicine, Vol 9 (2022)
Chronic kidney disease (CKD) is often accompanied by dyslipidemia, and abnormal lipid metabolism in proximal tubule cells is considered closely related to the dysfunction of proximal tubule cells and eventually leads to accelerated kidney damage. Nuc
Externí odkaz:
https://doaj.org/article/3025dbe925f14d67831093dd4fb97364
Autor:
Ting Liu, Chang-yan Li, Hao Chen, Juan Liu, Li-li Zhong, Ming-min Tang, Wen-bo Wang, Jin-ping Huang, Xu-shun Jiang
Publikováno v:
Heliyon, Vol 8, Iss 9, Pp e10515- (2022)
Aims: Oxidative stress plays a crucial role in podocyte injury in diabetic nephropathy (DN). tert-Butylhydroquinone (tBHQ) is an activator of Nrf2 that exerts protective effects in diabetic mice, but the underlying mechanism of tBHQ in the podocytes
Externí odkaz:
https://doaj.org/article/34a107172c954dedbd9d3be1baa693a3
Autor:
Ting Liu, Xue-mei Chen, Ji-ye Sun, Xu-shun Jiang, Yue Wu, Shan Yang, Hui-zhe Huang, Xiong-zhong Ruan, Xiao-gang Du
Publikováno v:
Kidney & Blood Pressure Research, Vol 43, Iss 1, Pp 206-219 (2018)
Background/Aims: Chronic kidney disease (CKD) is often accompanied by hyperlipidemia, which accelerates progression of the disease. Podocyte injury can lead to dysfunction of the glomerular filtration barrier, which is associated with proteinuria, a
Externí odkaz:
https://doaj.org/article/7b4237cb83bc4bad891073bb3a18851d
Autor:
Wang, Yu-Mei, Chen, Hong-Guang, Song, Mei, Xu, Shun-Jiang, Yu, Lu-Lu, Wang, Lan, Wang, Ran, Shi, Le, He, Jia, Huang, Yue-Qin, Sun, Hong-Qiang, Pan, Cheng-Ying, Wang, Xue-Yi *, Lu, Lin *
Publikováno v:
In Sleep Medicine March 2016 19:116-122
Autor:
Wei Hua, Lan Peng, Xue-mei Chen, Xu-Shun Jiang, Jian-Guo Hu, Xian-Hong Jiang, Xu Xiang, Jiang-min Wan, Yingfei Long, Jian-qiong Xiong, Xueyi ma, Xiao-gang Du
Background Lipid metabolism disorders lead to lipotoxicity. The kidney is one of the most vulnerable organs in hyperlipidemia. The hyperlipidemia-induced early stage of renal injury mainly manifests as podocyte damage. CD36 mediates fatty acid uptake
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::599a2e6cfcb1525c4e8b9962544de416
https://doi.org/10.21203/rs.3.rs-2454690/v1
https://doi.org/10.21203/rs.3.rs-2454690/v1
Publikováno v:
Journal of Cardiovascular Translational Research. 14:525-537
To investigate its effect and molecular regulatory mechanism on vascular calcification, EPO was added to vascular smooth muscle cells cultured in vitro and injected intraperitoneally into SD rats. The effect of EPO on VSMC calcification was determine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6d15d4c8182c4e751f0285abed84e600
https://doi.org/10.1007/s12265-020-10081-w
https://doi.org/10.1007/s12265-020-10081-w
Akademický článek
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Publikováno v:
Cell Death and Disease, Vol 11, Iss 5, Pp 1-18 (2020)
Cell Death & Disease
Cell Death & Disease
Diabetic nephropathy (DN) is the leading cause of end-stage renal disease (ESRD), and renal tubular cell dysfunction contributes to the pathogenesis of DN. Soluble epoxide hydrolase (sEH) is an enzyme that can hydrolyze epoxyeicosatrienoic acids (EET
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61e29d8ae09de3e5242e2fd43194a1b9
https://doi.org/10.1038/s41419-020-2594-x
https://doi.org/10.1038/s41419-020-2594-x
Autor:
Qiu-Nan Chen, Jing Wu, Zhen Fan, Yuxing Zhao, Qian Xiao, Jinliang Chen, Xu-shun Jiang, Yue Sun
Publikováno v:
Biochemical and biophysical research communications. 524(2)
Diabetes mellitus is a metabolic disorder that can lead to blood-brain barrier (BBB) disruption and cognitive decline. However, the mechanisms of BBB breakdown in diabetes are still unclear. Soluble epoxide hydrolase (sEH) is an enzyme that degrades
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f6e813971088aa4e4253c1f6f646f04
https://pubmed.ncbi.nlm.nih.gov/32001002
https://pubmed.ncbi.nlm.nih.gov/32001002