Zobrazeno 1 - 10
of 76
pro vyhledávání: '"Xu‐Ying Li"'
Autor:
Chaodong Wang, Hankui Liu, Xu-Ying Li, Jinghong Ma, Zhuqin Gu, Xiuli Feng, Shu Xie, Bei-Sha Tang, Shengdi Chen, Wei Wang, Jian Wang, Jianguo Zhang, Piu Chan
Publikováno v:
npj Parkinson's Disease, Vol 10, Iss 1, Pp 1-14 (2024)
Abstract While numerous single nucleotide variants and small indels have been identified in Parkinson’s disease (PD), the contribution of structural variants (SVs), copy number variants (CNVs), and short tandem repeats (STRs) remains poorly underst
Externí odkaz:
https://doaj.org/article/1e836f7c345f4b10b3cd864016ee6ea7
Autor:
Jie Zhong, Chaodong Wang, Dan Zhang, Xiaoli Yao, Quanzhen Zhao, Xusheng Huang, Feng Lin, Chun Xue, Yaqing Wang, Ruojie He, Xu-Ying Li, Qibin Li, Mingbang Wang, Shaoli Zhao, Shabbir Khan Afridi, Wenhao Zhou, Zhanjun Wang, Yanming Xu, Zhiheng Xu
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-22 (2024)
Abstract Amyotrophic lateral sclerosis (ALS) is a devastating neurodegenerative disease. To identify additional genetic factors, we analyzed exome sequences in a large cohort of Chinese ALS patients and found a homozygous variant (p.L700P) in PCDHA9
Externí odkaz:
https://doaj.org/article/898acf19f23c4dd2b6963d2441e74517
Autor:
Junge Zhu, Fanxi Xu, Hong Lai, Huiyao Yuan, Xu-Ying Li, Junya Hu, Wei Li, Lei Liu, Chaodong Wang
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-17 (2023)
Abstract Parkinson’s disease (PD) is characterized by α-synuclein aggregation in dopaminergic (DA) neurons, which are sensitive to oxidative stress. Mitochondria aconitase 2 (ACO2) is an essential enzyme in the tricarboxylic acid cycle that orches
Externí odkaz:
https://doaj.org/article/9a753059aab04b919913a9c46a77bd18
Autor:
Xu-Ying Li, Teng Xue, Hong Lai, Jing Dai, Fangda Peng, Fanxi Xu, Junge Zhu, Xian Li, Junya Hu, Wei Li, Raoli He, Lina Chen, Ying Chen, Chunguang Ding, Guoguang Zhao, Xianyang Chen, Qinyong Ye, Zhiheng Xu, Chaodong Wang
Publikováno v:
Heliyon, Vol 10, Iss 5, Pp e26588- (2024)
Introduction: Multiple system atrophy (MSA) is a rapidly progressing neurodegenerative disorder. Although diverse biomarkers have been established for Parkinson's disease (PD), no widely accepted markers have been identified in MSA. Pyruvate and lact
Externí odkaz:
https://doaj.org/article/0ec5ceec32a2431d9da71e119228c31e
Autor:
Liping Zhang, Xu‐Ying Li, Fanxi Xu, Lehong Gao, Zhanjun Wang, Xianling Wang, Xian Li, Mengyu Liu, Junge Zhu, Tingyan Yao, Jing Ye, Xiao‐Hong Qi, Yaqing Wang, Guoguang Zhao, Chaodong Wang, The Xuanwu Molecular Counselling Group for Neurogenetic Diseases
Publikováno v:
Molecular Genetics & Genomic Medicine, Vol 11, Iss 11, Pp n/a-n/a (2023)
Abstract Background Epilepsy (EP) is a common neurological disease in which 70–80% are thought to have a genetic cause. In patients with epilepsy, neurodevelopmental delay (NDD) was prevalent. Next generation of sequencing has been widely used in d
Externí odkaz:
https://doaj.org/article/37ef658f84c2493f8338eb6c381782b7
Autor:
Fanxi Xu, Sen Huang, Xu-Ying Li, Jianing Lin, Xiuli Feng, Shu Xie, Zhanjun Wang, Xian Li, Junge Zhu, Hong Lai, Yanming Xu, Xusheng Huang, Xiaoli Yao, Chaodong Wang
Publikováno v:
BMC Medical Genomics, Vol 15, Iss 1, Pp 1-12 (2022)
Abstract Background Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease characterized by predominant impairment of upper and lower motor neurons. Over 50 TARDBP mutations have been reported in both familial (FALS) and spora
Externí odkaz:
https://doaj.org/article/b71b36256afe434fb2174e8979307c79
Autor:
Hong Lai, Xu-Ying Li, Fanxi Xu, Junge Zhu, Xian Li, Yang Song, Xianlin Wang, Zhanjun Wang, Chaodong Wang
Publikováno v:
Brain Sciences, Vol 13, Iss 11, p 1546 (2023)
Background: Accurate diagnosis of Parkinson’s disease (PD) is challenging due to its diverse manifestations. Machine learning (ML) algorithms can improve diagnostic precision, but their generalizability across medical centers in China is underexplo
Externí odkaz:
https://doaj.org/article/d731331bf6fb48ee9212c07d59e8a679
Autor:
Feng Lin, Wanhui Lin, Chaofeng Zhu, Jilan Lin, Junge Zhu, Xu-Ying Li, Zhanjun Wang, Chaodong Wang, Huapin Huang
Publikováno v:
BMC Medical Genomics, Vol 14, Iss 1, Pp 1-8 (2021)
Abstract Background Amyotrophic lateral sclerosis (ALS) is a devastating neurodegenerative disease with neuronal cell inclusions composed of neurofilaments and other abnormal aggregative proteins as pathological hallmarks. Approximately 90% of patien
Externí odkaz:
https://doaj.org/article/cd0b5198e3b1446ca8569dc63bcc28d2
Publikováno v:
Guoji Yanke Zazhi, Vol 21, Iss 8, Pp 1319-1325 (2021)
AIM: To analyze the effect of ocular massage in patients after glaucoma filtering surgery.METHODS: Databases including the CNKI, VIP Information, WanFang and CBM were electronically searched for all randomized controlled trials(RCTs)about comparing t
Externí odkaz:
https://doaj.org/article/0e61e978aebb4747b7b5b800b7ce013a
Autor:
Hong Lai, Xu-Ying Li, Junya Hu, Wei Li, Fanxi Xu, Junge Zhu, Raoli He, Huidan Weng, Lina Chen, Jiao Yu, Xian Li, Yang Song, Xianling Wang, Zhanjun Wang, Rong Kang, Yuling Li, Junjie Xu, Yuanfei Deng, Qinyong Ye, Chaodong Wang
Publikováno v:
Frontiers in Neurology, Vol 13 (2022)
ObjectivesTo develop and validate a predictive nomogram for idiopathic rapid eye movement (REM) sleep behavior disorder (RBD) in a community population in Beijing, China.MethodsBased on the validated RBD questionnaire-Hong Kong (RBDQ-HK), we identifi
Externí odkaz:
https://doaj.org/article/cb79be3304b14ba49249fc17e5956f7d