Zobrazeno 1 - 10
of 90
pro vyhledávání: '"Xu‐Ming Mao"'
Autor:
Yi Han, Yaojie Guo, Nan Zhang, Fan Xu, Jarukitt Limwachiranon, Zhenzhen Xiong, Liru Xu, Xu-Ming Mao, Daniel H. Scharf
Publikováno v:
Communications Chemistry, Vol 7, Iss 1, Pp 1-10 (2024)
Abstract Fungal natural products from various species often feature hydroxamic acid motifs that have the ability to chelate iron. These compounds have an array of medicinally and ecologically relevant activities. Through genome mining, gene deletion
Externí odkaz:
https://doaj.org/article/44bf3fbbf15b4cdaab6071421912b4e0
Publikováno v:
Microbial Cell Factories, Vol 23, Iss 1, Pp 1-11 (2024)
Abstract Background Human lysozyme (hLYZ) is a natural antibacterial protein with broad applications in food and pharmaceutical industries. Recombinant production of hLYZ in Komagataella phaffii (K. phaffii) has attracted considerable attention, but
Externí odkaz:
https://doaj.org/article/a3cbb10efe604a749ef3ff83c0f755c9
Autor:
Bing-Bing Ma, Chen-Fan Sun, Jing-Yi Zhou, Shuai-Lei Gu, Xin-Yi Dai, Yan-Zhen Chen, Qing-Wei Zhao, Xu-Ming Mao
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-10 (2023)
Abstract Protein post-translational modifications (PTMs) with various acyl groups play central roles in Streptomyces. But whether these acyl groups can be further modified, and the influences of these potential modifications on bacterial physiology h
Externí odkaz:
https://doaj.org/article/5d8fd8237b3f4219bd0048eed7e6f80f
Autor:
Jiao-Le Fang, Wen-Li Gao, Wei-Feng Xu, Zhong-Yuan Lyu, Lie Ma, Shuai Luo, Xin-Ai Chen, Xu-Ming Mao, Yong-Quan Li
Publikováno v:
Synthetic and Systems Biotechnology, Vol 7, Iss 4, Pp 1013-1023 (2022)
Despite numerous studies on transcriptional level regulation by single genes in drug producing Actinomyces, the global regulation based on epigenetic modification is not well explored. N4-methylcytosine (m4C), an abundant epigenetic marker in Actinom
Externí odkaz:
https://doaj.org/article/fc233d9e346e4fc092beb08ab7219152
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 11 (2023)
Streptomyces is renowned for its abundant production of bioactive secondary metabolites, but most of these natural products are produced in low yields. Traditional rational network refactoring is highly dependent on the comprehensive understanding of
Externí odkaz:
https://doaj.org/article/259895fa99534d2881dac35aeefbcdf8
Publikováno v:
BMC Genomics, Vol 21, Iss 1, Pp 1-13 (2020)
Abstract Background Secondary metabolites as natural products from endophytic fungi are important sources of pharmaceuticals. However, there is currently little understanding of endophytic fungi at the omics levels about their potential in secondary
Externí odkaz:
https://doaj.org/article/f5801cc6e5e146789c91994f7d5b553a
Autor:
Qing-Ting Bu, Yue-Ping Li, Huang Xie, Jue Wang, Zi-Yue Li, Xin-Ai Chen, Xu-Ming Mao, Yong-Quan Li
Publikováno v:
Microbial Cell Factories, Vol 19, Iss 1, Pp 1-12 (2020)
Abstract Background Large-scale genome reduction has been performed to significantly improve the performance of microbial chassis. Identification of the essential or dispensable genes is pivotal for genome reduction to avoid synthetic lethality. Here
Externí odkaz:
https://doaj.org/article/e246cb5d99fd4ddd819ce94bfaefdcbb
Autor:
Yun Li, Xing Chang, Xu-Ming Mao, Wei Du, Yue-Ping Zeng, Xie Yuan, Jun Li, Li Jia, Tao Zhang, Yong Xie, Qing Li, Qiu-Ning Sun, Li-Shao Guo
Publikováno v:
Chinese Medical Journal, Vol 134, Iss 5, Pp 616-618 (2021)
Externí odkaz:
https://doaj.org/article/9a14fddfab964f1eb9e20b65742d6806
Autor:
Yun Li, Wen-Jun Wang, Wei-Wei Chen, Xue Fan, Lu Cao, Ze-Yu Xing, Qi Zhen, Qiong-Qiong Xu, Chen-Yu Zhu, Hui-Yao Ge, Dian Chen, Rui-Xue Zhang, Chang Shu, Wei Du, Shi-Rui Chen, Xie Yuan, Hui Zhang, Xia Hu, Xu-Ming Mao, Qiu-Ning Sun, Ning-Ning Wang
Publikováno v:
Chinese Medical Journal, Vol 133, Iss 19, Pp 2370-2372 (2020)
Externí odkaz:
https://doaj.org/article/4454ab4e52ea4aba99ec24e66f066408
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-9 (2019)
Azoxy bonds are frequently found in liquid crystals, chemical intermediates, dyes, agrochemicals and pharmaceuticals. Here, the authors investigated azoxy bond formation by the non-heme diiron N-oxygenase AzoC in azoxymycin biosynthesis and show that
Externí odkaz:
https://doaj.org/article/226e496179d24ce0b09894bc7d0f768e