Zobrazeno 1 - 10
of 213
pro vyhledávání: '"Xose S Puente"'
Autor:
Gonzalo Hernández, María José Ramírez, Jordi Minguillón, Paco Quiles, Gorka Ruiz de Garibay, Miriam Aza-Carmona, Massimo Bogliolo, Roser Pujol, Rosario Prados-Carvajal, Juana Fernández, Nadia García, Adrià López, Sara Gutiérrez-Enríquez, Orland Diez, Javier Benítez, Mónica Salinas, Alex Teulé, Joan Brunet, Paolo Radice, Paolo Peterlongo, Detlev Schindler, Pablo Huertas, Xose S Puente, Conxi Lázaro, Miquel Àngel Pujana, Jordi Surrallés
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
Mutations in BRCA1 are associated with an increased risk of breast and ovarian cancer. Here the authors show that EDC4, a component of P-bodies, is a member of the BRCA1 complex with roles in stimulating end resection at breaks.
Externí odkaz:
https://doaj.org/article/9dd58df3757244329f9ae097492e7706
Autor:
Ece Özoğul, Anna Montaner, Melina Pol, Gerard Frigola, Olga Balagué, Charlotte Syrykh, Pablo Bousquets-Muñoz, Romina Royo, Juliette Fontaine, Alexandra Traverse-Glehen, Marco M. Bühler, Luca Giudici, Marco Roncador, Thorsten Zenz, Sylvain Carras, Severine Valmary-Degano, Laurence de Leval, Jan Bosch-Schips, Fina Climent, Julia Salmeron-Villalobos, Melika Bashiri, Silvia Ruiz-Gaspà, Dolors Costa, Sílvia Beà, Itziar Salaverria, Eva Giné, Leticia Quintanilla-Martinez, Pierre Brousset, Mark Raffeld, Elaine S. Jaffe, Xose S. Puente, Cristina López, Ferran Nadeu, Elias Campo
Publikováno v:
Blood Cancer Journal, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract Mantle cell lymphoma (MCL) is genetically characterized by the IG::CCND1 translocation mediated by an aberrant V(D)J rearrangement. CCND1 translocations and overexpression have been identified in occasional aggressive B-cell lymphomas with u
Externí odkaz:
https://doaj.org/article/ebc32ff445d443efa40b812995ecadc9
Autor:
Joan Castellsagué, Bernat Gel, Juana Fernández‐Rodríguez, Roger Llatjós, Ignacio Blanco, Yolanda Benavente, Diana Pérez‐Sidelnikova, Javier García‐del Muro, Joan Maria Viñals, August Vidal, Rafael Valdés‐Mas, Ernest Terribas, Adriana López‐Doriga, Miguel Angel Pujana, Gabriel Capellá, Xose S Puente, Eduard Serra, Alberto Villanueva, Conxi Lázaro
Publikováno v:
EMBO Molecular Medicine, Vol 7, Iss 5, Pp 608-627 (2015)
Abstract Malignant peripheral nerve sheath tumors (MPNSTs) are soft‐tissue sarcomas that can arise either sporadically or in association with neurofibromatosis type 1 (NF1). These aggressive malignancies confer poor survival, with no effective ther
Externí odkaz:
https://doaj.org/article/be1d8de904314c26af44605843b3d9f7
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e51422 (2012)
Exome sequencing constitutes an important technology for the study of human hereditary diseases and cancer. However, the ability of this approach to identify copy number alterations in primary tumor samples has not been fully addressed. Here we show
Externí odkaz:
https://doaj.org/article/2b0816cc8fb04c548861415947af7041
Resistance to bleomycin-induced lung fibrosis in MMP-8 deficient mice is mediated by interleukin-10.
Autor:
Emilio García-Prieto, Adrián González-López, Sandra Cabrera, Aurora Astudillo, Ana Gutiérrez-Fernández, Miriam Fanjul-Fernandez, Estefanía Batalla-Solís, Xose S Puente, Antonio Fueyo, Carlos López-Otín, Guillermo M Albaiceta
Publikováno v:
PLoS ONE, Vol 5, Iss 10, p e13242 (2010)
BACKGROUND: Matrix metalloproteinases (MMPs) may have pro and antifibrotic roles within the lungs, due to its ability to modulate collagen turnover and immune mediators. MMP-8 is a collagenase that also cleaves a number of cytokines and chemokines. M
Externí odkaz:
https://doaj.org/article/5b7768d5472f4696aa696a4237a03c84
Autor:
Angus M Tester, Jennifer H Cox, Andrea R Connor, Amanda E Starr, Richard A Dean, Xose S Puente, Carlos López-Otín, Christopher M Overall
Publikováno v:
PLoS ONE, Vol 2, Iss 3, p e312 (2007)
We identify matrix metalloproteinase (MMP)-8, the polymorphonuclear (PMN) leukocyte collagenase, as a critical mediator initiating lipopolysaccharide (LPS)-responsiveness in vivo. PMN infiltration towards LPS is abrogated in Mmp8-null mice. MMP-8 cle
Externí odkaz:
https://doaj.org/article/43867c694e834ccb82d6c92d53dbe95f
Autor:
José Baselga, Joan Seoane, Maurizio Scaltriti, Paolo Nuciforo, Ludmila Prudkin, Joaquín Arribas, Javier Hernández-Losa, Judit Grueso, Leticia De Mattos-Arruda, Josep-Lluís Parra, Ginevra Caratù, Daniel Silberschmidt, Enriqueta Felip, Xose S. Puente, Ana Vivancos, Violeta Serra
Supplementary Table 1 - XLSX 39K, Exome sequencing results. The table contains the raw data for Figure 2B as well as the mutation allele frequency, the prediction of protein functionality, the inclusion in the Cancer Gene Census and the protein funct
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1abca89c748d1b366ff73c1756de4a72
https://doi.org/10.1158/2159-8290.22528589.v1
https://doi.org/10.1158/2159-8290.22528589.v1
Autor:
José Baselga, Joan Seoane, Maurizio Scaltriti, Paolo Nuciforo, Ludmila Prudkin, Joaquín Arribas, Javier Hernández-Losa, Judit Grueso, Leticia De Mattos-Arruda, Josep-Lluís Parra, Ginevra Caratù, Daniel Silberschmidt, Enriqueta Felip, Xose S. Puente, Ana Vivancos, Violeta Serra
Supplementary Figures - PDF file 585K, Supplementary Figure 1. Fluorescence in situ hybridization (FISH) of HER2. Supplementary Figure 2. EGFR and HER2 mutations identified. Supplementary Figure 3. Comparisons of allele frequencies. Supplementary Fig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7ae505adb14b92ed9fa81e783d88ed5
https://doi.org/10.1158/2159-8290.22528592
https://doi.org/10.1158/2159-8290.22528592
Autor:
Eva González-Suárez, Xose S. Puente, Michael T. Lewis, Miguel Angel Pujana, Violeta Serra, Cristina Cruz, Judith Balmaña, Anna Petit, María Teresa Soler-Monso, Joaquín Arribas, Carlos Caldas, Alejandra Bruna, Aleix Prat, Laia Paré, Purificación Muñoz, Eva M. Trinidad, Alejandro Collado-Sole, Gerburg M. Wulf, Bing Zhang, Suhas Vasaikar, Chen Huang, Lacey E. Dobrolecki, Marta Palafox, Luis Palomero, Sergi Beltran, Raul Tonda, Ander Díaz-Navarro, Jorge Gómez-Miragaya
Supplementary methods and legends for supplementary figures
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35c459f478caf89ee13f2a4d0789fe97
https://doi.org/10.1158/0008-5472.22421748.v1
https://doi.org/10.1158/0008-5472.22421748.v1
Autor:
Eva González-Suárez, Xose S. Puente, Michael T. Lewis, Miguel Angel Pujana, Violeta Serra, Cristina Cruz, Judith Balmaña, Anna Petit, María Teresa Soler-Monso, Joaquín Arribas, Carlos Caldas, Alejandra Bruna, Aleix Prat, Laia Paré, Purificación Muñoz, Eva M. Trinidad, Alejandro Collado-Sole, Gerburg M. Wulf, Bing Zhang, Suhas Vasaikar, Chen Huang, Lacey E. Dobrolecki, Marta Palafox, Luis Palomero, Sergi Beltran, Raul Tonda, Ander Díaz-Navarro, Jorge Gómez-Miragaya
Docetaxel response on TNBC cell lines with ETV6 and GABARAPL1 overexpression and knockdown
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a8c8345a1ddeb9a7b70d6b65550935a
https://doi.org/10.1158/0008-5472.22421757
https://doi.org/10.1158/0008-5472.22421757