Zobrazeno 1 - 10
of 212
pro vyhledávání: '"Xose S, Puente"'
Autor:
Ece Özoğul, Anna Montaner, Melina Pol, Gerard Frigola, Olga Balagué, Charlotte Syrykh, Pablo Bousquets-Muñoz, Romina Royo, Juliette Fontaine, Alexandra Traverse-Glehen, Marco M. Bühler, Luca Giudici, Marco Roncador, Thorsten Zenz, Sylvain Carras, Severine Valmary-Degano, Laurence de Leval, Jan Bosch-Schips, Fina Climent, Julia Salmeron-Villalobos, Melika Bashiri, Silvia Ruiz-Gaspà, Dolors Costa, Sílvia Beà, Itziar Salaverria, Eva Giné, Leticia Quintanilla-Martinez, Pierre Brousset, Mark Raffeld, Elaine S. Jaffe, Xose S. Puente, Cristina López, Ferran Nadeu, Elias Campo
Publikováno v:
Blood Cancer Journal, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract Mantle cell lymphoma (MCL) is genetically characterized by the IG::CCND1 translocation mediated by an aberrant V(D)J rearrangement. CCND1 translocations and overexpression have been identified in occasional aggressive B-cell lymphomas with u
Externí odkaz:
https://doaj.org/article/ebc32ff445d443efa40b812995ecadc9
Autor:
Elena María Fernández-Garnacho, Ferran Nadeu, Silvia Martín, Pablo Mozas, Andrea Rivero, Julio Delgado, Eva Giné, Armando López-Guillermo, Martí Duran-Ferrer, Itziar Salaverria, Cristina López, Sílvia Beà, Santiago Demajo, Pedro Jares, Xose S. Puente, José Ignacio Martín-Subero, Elías Campo, Lluís Hernández
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract MALAT1 long non-coding RNA has oncogenic roles but has been poorly studied in indolent B-cell neoplasms. Here, MALAT1 expression was analyzed using RNA-seq, microarrays or qRT-PCR in primary samples from clinico-biological subtypes of chroni
Externí odkaz:
https://doaj.org/article/ae1ddb4b3027446b8ee9e79f800947ba
Autor:
Romina Royo, Laura Magnano, Julio Delgado, Sara Ruiz-Gil, Josep Ll. Gelpí, Holger Heyn, Malcom A. Taylor, Tatjana Stankovic, Xose S. Puente, Ferran Nadeu, Elías Campo
Publikováno v:
Blood Cancer Journal, Vol 12, Iss 6, Pp 1-4 (2022)
Externí odkaz:
https://doaj.org/article/5ce53c0fe1404f738daf8cc784bcc0be
Autor:
Pablo Bousquets-Muñoz, Ander Díaz-Navarro, Ferran Nadeu, Ana Sánchez-Pitiot, Sara López-Tamargo, Shimin Shuai, Milagros Balbín, Jose M. C. Tubio, Sílvia Beà, Jose I. Martin-Subero, Ana Gutiérrez-Fernández, Lincoln D. Stein, Elías Campo, Xose S. Puente
Publikováno v:
npj Genomic Medicine, Vol 7, Iss 1, Pp 1-12 (2022)
Abstract Current somatic mutation callers are biased against repetitive regions, preventing the identification of potential driver alterations in these loci. We developed a mutation caller for repetitive regions, and applied it to study repetitive no
Externí odkaz:
https://doaj.org/article/5f0f3806b2a34e4faaa729f3e687de20
Autor:
Even H. Rustad, Ferran Nadeu, Nicos Angelopoulos, Bachisio Ziccheddu, Niccolò Bolli, Xose S. Puente, Elias Campo, Ola Landgren, Francesco Maura
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-12 (2021)
Rustad et al. present a software package for the R statistical environment for the accurately quantify of somatic mutational signatures in hematological malignancies
Externí odkaz:
https://doaj.org/article/1798eaafba7b4603af2c13853c09ffc6
Autor:
Laura Escudero, Anna Llort, Alexandra Arias, Ander Diaz-Navarro, Francisco Martínez-Ricarte, Carlota Rubio-Perez, Regina Mayor, Ginevra Caratù, Elena Martínez-Sáez, Élida Vázquez-Méndez, Iván Lesende-Rodríguez, Raquel Hladun, Luis Gros, Santiago Ramón y Cajal, Maria A. Poca, Xose S. Puente, Juan Sahuquillo, Soledad Gallego, Joan Seoane
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
Non-invasive and precise methods are critical for monitoring paediatric brain cancers. Here the authors show that the molecular alterations and heterogeneity of paediatric medulloblastomas can be reliably detected in circulating tumour DNA from the c
Externí odkaz:
https://doaj.org/article/c3bf556831fd4765979786b61390d38a
Autor:
Ferran Nadeu, Rut Mas-de-les-Valls, Alba Navarro, Romina Royo, Silvia Martín, Neus Villamor, Helena Suárez-Cisneros, Rosó Mares, Junyan Lu, Anna Enjuanes, Alfredo Rivas-Delgado, Marta Aymerich, Tycho Baumann, Dolors Colomer, Julio Delgado, Ryan D. Morin, Thorsten Zenz, Xose S. Puente, Peter J. Campbell, Sílvia Beà, Francesco Maura, Elías Campo
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
Immunoglobulin (Ig) rearrangement and translocation information are usually obtained by targeted sequencing of the respective loci. Here, the authors present the IgCaller algorithm, which extracts Ig heavy and light chain genetic properties from shor
Externí odkaz:
https://doaj.org/article/60cf64de4d48413e9c6aa1237bafd86b
Autor:
Even H. Rustad, Venkata Yellapantula, Daniel Leongamornlert, Niccolò Bolli, Guy Ledergor, Ferran Nadeu, Nicos Angelopoulos, Kevin J. Dawson, Thomas J. Mitchell, Robert J. Osborne, Bachisio Ziccheddu, Cristiana Carniti, Vittorio Montefusco, Paolo Corradini, Kenneth C. Anderson, Philippe Moreau, Elli Papaemmanuil, Ludmil B. Alexandrov, Xose S. Puente, Elias Campo, Reiner Siebert, Herve Avet-Loiseau, Ola Landgren, Nikhil Munshi, Peter J. Campbell, Francesco Maura
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
The initial mutational processes and how these lead to progression in multiple myeloma (MM) are unclear. Here, the authors identify mutational signatures that occur over time in a large cohort of MM patients and suggest features that may help in earl
Externí odkaz:
https://doaj.org/article/5bcecbd98cdc4f9fbf76239987880049
Autor:
Romina Royo, Laura Magnano, Julio Delgado, Sara Ruiz-Gil, Josep Ll. Gelpí, Holger Heyn, Malcom A. Taylor, Tatjana Stankovic, Xose S. Puente, Ferran Nadeu, Elías Campo
Publikováno v:
Blood Cancer Journal, Vol 12, Iss 12, Pp 1-1 (2022)
Externí odkaz:
https://doaj.org/article/ef04f835f5f044efba0d338569c8d231
Autor:
Helen E. Speedy, Renée Beekman, Vicente Chapaprieta, Giulia Orlando, Philip J. Law, David Martín-García, Jesús Gutiérrez-Abril, Daniel Catovsky, Sílvia Beà, Guillem Clot, Montserrat Puiggròs, David Torrents, Xose S. Puente, James M. Allan, Carlos López-Otín, Elias Campo, Richard S. Houlston, José I. Martín-Subero
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-9 (2019)
The definition of regulatory landscape at chronic lymphocytic leukaemia (CLL) risk loci is limited. Here, the authors perform an epigenomic characterisation of 42 known risk loci in CLL and normal B cells at different developmental stages and show ac
Externí odkaz:
https://doaj.org/article/9b5b6327af3c440e9c59830da14206ad