Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Xiyun Jin"'
Autor:
Qian Ding, Wenyi Yang, Guangfu Xue, Hongxin Liu, Yideng Cai, Jinhao Que, Xiyun Jin, Meng Luo, Fenglan Pang, Yuexin Yang, Yi Lin, Yusong Liu, Haoxiu Sun, Renjie Tan, Pingping Wang, Zhaochun Xu, Qinghua Jiang
Publikováno v:
Genome Biology, Vol 25, Iss 1, Pp 1-36 (2024)
Abstract Advances in single-cell transcriptomics provide an unprecedented opportunity to explore complex biological processes. However, computational methods for analyzing single-cell transcriptomics still have room for improvement especially in dime
Externí odkaz:
https://doaj.org/article/1acf3ecb89144f69bb113bc2a6df2a95
Autor:
Wenyi Yang, Pingping Wang, Shouping Xu, Tao Wang, Meng Luo, Yideng Cai, Chang Xu, Guangfu Xue, Jinhao Que, Qian Ding, Xiyun Jin, Yuexin Yang, Fenglan Pang, Boran Pang, Yi Lin, Huan Nie, Zhaochun Xu, Yong Ji, Qinghua Jiang
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract The inference of cell–cell communication (CCC) is crucial for a better understanding of complex cellular dynamics and regulatory mechanisms in biological systems. However, accurately inferring spatial CCCs at single-cell resolution remains
Externí odkaz:
https://doaj.org/article/d5f02cc0b72b462c9dd2a7d430e53925
Autor:
Yunlong He, Depeng Yang, Xiaoyu Lin, Jinfeng Zhang, Rui Cheng, Liangyu Cao, Lijun Yang, Mengmeng Zhang, Xinyue Shi, Xiyun Jin, Handi Sun, Haoxiu Sun, Jingyu Zang, Yu Li, Jianqun Ma, Huan Nie
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
BackgroundEsophageal cancer (ESCA) is one of the most common tumors in the world, and treatment using neoadjuvant therapy (NT) based on radiotherapy and/or chemotherapy has still unsatisfactory results. Neoadjuvant immunochemotherapy (NICT) has also
Externí odkaz:
https://doaj.org/article/86b4897af3d4459eb5a5b76221b40e56
Autor:
Lixing Xiao, Haoxiu Sun, Rui Cheng, Rongrong Yang, Xiyun Jin, Zhaochun Xu, Yideng Cai, Yuexin Yang, Fenglan Pang, Guangfu Xue, Pingping Wang, Qinghua Jiang, Huan Nie
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 35, Iss 1, Pp 102129- (2024)
Circulating tumor cells (CTCs) that undergo epithelial-to-mesenchymal transition (EMT) can provide valuable information regarding metastasis and potential therapies. However, current studies on the EMT overlook alternative splicing. Here, we used sin
Externí odkaz:
https://doaj.org/article/3e4576260e4743abbe980deda0e6af15
Autor:
Xiyun Jin, Yideng Cai, Guangfu Xue, Jinhao Que, Rui Cheng, Yuexin Yang, Lixing Xiao, Xiaoyu Lin, Chang Xu, Pingping Wang, Zhaochun Xu, Huan Nie, Qinghua Jiang
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 32, Iss , Pp 189-202 (2023)
Tumor-infiltrating T cells are essential players in tumor immunotherapy. Great progress has been achieved in the investigation of T cell heterogeneity. However, little is well known about the shared characteristics of tumor-infiltrating T cells acros
Externí odkaz:
https://doaj.org/article/50d144dff6294c4f8ad45366b5e1470c
Autor:
Pingping Wang, Lifen Yao, Meng Luo, Wenyang Zhou, Xiyun Jin, Zhaochun Xu, Shi Yan, Yiqun Li, Chang Xu, Rui Cheng, Yan Huang, Xiaoyu Lin, Kexin Ma, Huimin Cao, Hongxin Liu, Guangfu Xue, Fang Han, Huan Nie, Qinghua Jiang
Publikováno v:
Cell Discovery, Vol 7, Iss 1, Pp 1-16 (2021)
Abstract Given the chronic inflammatory nature of Parkinson’s disease (PD), T cell immunity may be important for disease onset. Here, we performed single-cell transcriptome and TCR sequencing, and conducted integrative analyses to decode compositio
Externí odkaz:
https://doaj.org/article/e479b76060ba44c7bf9bf381d3313824
Autor:
Lixing Xiao, Guoying Zou, Rui Cheng, Pingping Wang, Kexin Ma, Huimin Cao, Wenyang Zhou, Xiyun Jin, Zhaochun Xu, Yan Huang, Xiaoyu Lin, Huan Nie, Qinghua Jiang
Publikováno v:
BMC Cancer, Vol 21, Iss 1, Pp 1-13 (2021)
Abstract Backgroud Cancer stemness is associated with metastases in kidney renal clear cell carcinoma (KIRC) and negatively correlates with immune infiltrates. Recent stemness evaluation methods based on the absolute expression have been proposed to
Externí odkaz:
https://doaj.org/article/79e91d703bcc420fb2d0b3bc36e4e39f
Autor:
Pingping Wang, Meng Luo, Wenyang Zhou, Xiyun Jin, Zhaochun Xu, Shi Yan, Yiqun Li, Chang Xu, Rui Cheng, Yan Huang, Xiaoyu Lin, Lifen Yao, Huan Nie, Qinghua Jiang
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Immune system plays important roles in the pathogenesis of Parkinson’s disease (PD). However, the role of B cells in this complex disease are still not fully understood. B cells produce antibodies but can also regulate immune responses. In order to
Externí odkaz:
https://doaj.org/article/13a0eb54b78a421eafa98d48db9ff54c
Autor:
Wenyang Zhou, Chang Xu, Pingping Wang, Meng Luo, Zhaochun Xu, Rui Cheng, Xiyun Jin, Yu Guo, Guangfu Xue, Liran Juan, Anastasia A. Anashkina, Huan Nie, Qinghua Jiang
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), causing an outbreak of coronavirus disease 2019 (COVID-19), has been undergoing various mutations. The analysis of the structural and energetic effects of mutations on protein-protein inte
Externí odkaz:
https://doaj.org/article/37ba098766774e3f8f952d10746acd84
Autor:
Xiaoyu Lin, Tiantongfei Jiang, Jing Bai, Junyi Li, Tianshi Wang, Jun Xiao, Yi Tian, Xiyun Jin, Tingting Shao, Juan Xu, Lingchao Chen, Lihua Wang, Yongsheng Li
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 13, Iss , Pp 620-632 (2018)
Long noncoding RNAs (lncRNAs) have been implicated in cancer biogenesis and prognosis. However, we still lack knowledge on their function during glioma progression. In this study, we analyzed the lncRNA expression profile across 907 glioma patients i
Externí odkaz:
https://doaj.org/article/b4cb468ea9b64742a26672a5814ca497