Zobrazeno 1 - 10
of 131
pro vyhledávání: '"Xiyun Deng"'
Autor:
Chanjuan Zheng, Xi Xu, Muyao Wu, Lian Xue, Jianyu Zhu, Hongzhuo Xia, Siyu Ding, Shujun Fu, Xinyu Wang, Yian Wang, Guangchun He, Xia Liu, Xiyun Deng
Publikováno v:
Breast Cancer Research, Vol 25, Iss 1, Pp 1-12 (2023)
Abstract Triple-negative breast cancer (TNBC) is the most lethal subtype of breast cancer, with limited therapeutic options readily available. Immunotherapy such as immune checkpoint inhibition has been investigated in TNBC but still encounters low o
Externí odkaz:
https://doaj.org/article/329c0ea15a924f1ba7c3fd68b0412c62
Autor:
Yifan Tang, Huicong Feng, Lupeng Zhang, Chiwen Qu, Jinlong Li, Xiangyu Deng, Suye Zhong, Jun Yang, Xiyun Deng, Xiaomin Zeng, Yiren Wang, Xiaoning Peng
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-13 (2022)
Abstract Abundant evidence has indicated that the prognosis of cutaneous melanoma (CM) patients is highly complicated by the tumour immune microenvironment. We retrieved the clinical data and gene expression data of CM patients in The Cancer Genome A
Externí odkaz:
https://doaj.org/article/fc2de477754f41e2ac0420c264996a32
Autor:
Sufang Wu, Hua He, Jingjing Huang, Shiyao Jiang, Xiyun Deng, Jun Huang, Yuanbing Chen, Yiqun Jiang
Publikováno v:
Mathematical Biosciences and Engineering, Vol 19, Iss 9, Pp 9295-9320 (2022)
WW domain-containing transcription regulator 1 (TAZ, or WWTR1) and Yes-associated protein 1 (YAP) are both important effectors of the Hippo pathway and exhibit different functions. However, few studies have explored their co-regulatory mechanisms in
Externí odkaz:
https://doaj.org/article/176c307b5b2c4c3da0ac4f91d39d7db2
Publikováno v:
Frontiers in Medicine, Vol 10 (2023)
BackgroundTriple-negative breast cancer (TNBC) is proposed at the beginning of this century, which is still the most challenging breast cancer subtype due to its aggressive behavior, including early relapse, metastatic spread, and poor survival. This
Externí odkaz:
https://doaj.org/article/1826c1c035ee4d2ea8c29cabb56ff627
Editorial: Triple-negative breast cancer: Heterogeneity, tumor microenvironment and targeted therapy
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Externí odkaz:
https://doaj.org/article/aa7ca0f897534d8d80edfe5aadd8f47a
Autor:
Zhe-Yu Hu, Chanjuan Zheng, Jianbo Yang, Siyu Ding, Can Tian, Ning Xie, Lian Xue, Muyao Wu, Shujun Fu, Zhouzhou Rao, Matthew A. Price, James B. McCarthy, Quchang Ouyang, Jizhen Lin, Xiyun Deng
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
BackgroundIn triple-negative breast cancer (TNBC), PDL1/PD1-directed immunotherapy is effective in less than 20% of patients. In our preliminary study, we have found CSPG4 to be highly expressed together with PDL1 in TNBCs, particularly those harbori
Externí odkaz:
https://doaj.org/article/b7cfdf35a298478e972b0d82645af35b
Autor:
Sisi Chen, Ying Li, Muyao Wu, Lian Xue, Jianyu Zhu, Mi Wu, Qiuting Zhang, Guangchun He, Guifei Li, Shujun Fu, Chanjuan Zheng, Xiyun Deng
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Triple-negative breast cancer (TNBC) is the most aggressive subtype of breast cancer and lacks approved specific targeted therapies. One of the major reasons why TNBC is difficult to treat is the high proportion of cancer stem cells within the tumor
Externí odkaz:
https://doaj.org/article/d91171f1e06a4659a27b4ff65a13c8f4
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Triple-negative breast cancer (TNBC) is the most aggressive subtype of breast cancer, which is characterized by the absence of estrogen receptor (ER) and progesterone receptor (PR) expression and the absence of human epidermal growth factor receptor
Externí odkaz:
https://doaj.org/article/e05da0bf9a0d4d04af9f45affada38a9
Autor:
Chanjuan Zheng, Shichao Yan, Lu Lu, Hui Yao, Guangchun He, Sisi Chen, Ying Li, Xiaojun Peng, Zhongyi Cheng, Mi Wu, Qiuting Zhang, Guifei Li, Shujun Fu, Xiyun Deng
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Triple-negative breast cancer (TNBC) is more aggressive and has poorer prognosis compared to other subtypes of breast cancer. Epithelial-to-mesenchymal transition (EMT) is a process in which epithelial cells transform into mesenchymal-like cells capa
Externí odkaz:
https://doaj.org/article/e16093c6b47d46bc82145fe20cfb7651
Autor:
Di Wu, Yao Chen, Shun Wen, Yi Wen, Rong Wang, Qiuting Zhang, Ge Qin, Huimei Yi, Mi Wu, Lu Lu, Xiaojun Tao, Xiyun Deng
Publikováno v:
Nanoscale Research Letters, Vol 14, Iss 1, Pp 1-12 (2019)
Abstract Triple-negative breast cancer (TNBC) is a subtype of breast cancer that is prone to drug resistance and difficult to treat. In this study, we grafted water-soluble pullulan with lovastatin (LV) to develop a novel amphiphilic conjugate, pullu
Externí odkaz:
https://doaj.org/article/ef773caee3c649cda6518e844d51c1a2