Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Xiyue Xiao"'
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 14, Iss 6, Pp 2447-2474 (2024)
The clinical efficacy of current cancer therapies falls short, and there is a pressing demand to integrate new targets with conventional therapies. Autophagy, a highly conserved self-degradation process, has received considerable attention as an emer
Externí odkaz:
https://doaj.org/article/b5671894752c447fa00ea89912621cbf
Publikováno v:
PLoS ONE, Vol 12, Iss 3, p e0173194 (2017)
BACKGROUND:The death-associated protein kinase (DAPK) is a tumor suppressor gene, which is a mediator of cell death of INF-γ-induced apoptosis. Aberrant methylation of DAPK promoter has been reported in patients with head and neck squamous cell carc
Externí odkaz:
https://doaj.org/article/cf030ccea7e547dea4b164512eea40b9
Publikováno v:
PLoS ONE, Vol 11, Iss 9, p e0163534 (2016)
O6-methylguanine-DNA methyl-transferase (MGMT) gene, a DNA repair gene, plays a critical role in the repair of alkylated DNA adducts that form following exposure to genotoxic agents. MGMT is generally expressed in various tumors, and its function is
Externí odkaz:
https://doaj.org/article/28b204bdc2274cd2911fa0f5db0fd083
Publikováno v:
PLoS ONE, Vol 11, Iss 9, p e0163257 (2016)
BACKGROUND:Ovarian cancer is the primary cause of death in women diagnosed with gynecological malignancies worldwide. Absence of early symptoms prevents prompt diagnosis or successful therapeutic intervention. P16INK4a is a well-known tumor suppresso
Externí odkaz:
https://doaj.org/article/4eb96ab1aad745d588815bf501480a84
Publikováno v:
European Archives of Oto-Rhino-Laryngology. 280:2091-2097
Publikováno v:
PLoS ONE, Vol 12, Iss 3, p e0173194 (2017)
PLoS ONE
PLoS ONE
Background The death-associated protein kinase (DAPK) is a tumor suppressor gene, which is a mediator of cell death of INF-γ–induced apoptosis. Aberrant methylation of DAPK promoter has been reported in patients with head and neck squamous cell ca
Publikováno v:
PLoS ONE, Vol 11, Iss 9, p e0163534 (2016)
PLoS ONE
PLoS ONE
BACKGROUND O6-methylguanine-DNA methyl-transferase (MGMT) gene, a DNA repair gene, plays a critical role in the repair of alkylated DNA adducts that form following exposure to genotoxic agents. MGMT is generally expressed in various tumors, and its f
Publikováno v:
PLoS ONE, Vol 11, Iss 9, p e0163257 (2016)
PLoS ONE
PLoS ONE
BACKGROUND:Ovarian cancer is the primary cause of death in women diagnosed with gynecological malignancies worldwide. Absence of early symptoms prevents prompt diagnosis or successful therapeutic intervention. P16INK4a is a well-known tumor suppresso