Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Xiyao Cheng"'
Autor:
Ting Zhou, Zhiqiang Ke, Qianqian Ma, Jiani Xiang, Meng Gao, Yongqi Huang, Xiyao Cheng, Zhengding Su
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-9 (2023)
Abstract The tumor suppressor p53 (p53) is regulated by murine double minute 2 (Mdm2) and its homologous MdmX in maintaining the basal level of p53. Overexpressed Mdm2/MdmX inhibits cellular p53 activity, which is highly relevant to cancer occurrence
Externí odkaz:
https://doaj.org/article/186b78f4bdd6492d8d1d07a51cc30901
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 19, p 10820 (2024)
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the virus that causes COVID-19, and so far, it has occurred five noteworthy variants of concern (VOC). SARS-CoV-2 invades cells by contacting its Spike (S) protein to its receptor on the
Externí odkaz:
https://doaj.org/article/2583368f6625416aa5fce60ed2db2c3c
Publikováno v:
Microbial Cell Factories, Vol 22, Iss 1, Pp 1-15 (2023)
Abstract 4-Androstene-3,17-dione (4-AD) and 22-hydroxy-23,24-bisnorchol-4-ene-3-one (BA) are the most important and representative C19- and C22-steroidal materials. The optimalization of sterol production with mycobacterial phytosterol conversion has
Externí odkaz:
https://doaj.org/article/98287f4ccae24285822641b97da1bdb5
Publikováno v:
BioTechniques, Vol 73, Iss 2, Pp 80-89 (2022)
Cellular protein–protein interactions are largely dependent on the activities of signaling proteins. Here, we present a technique to tune gene expression at translation level based on G418-inducible readthrough premature termination codon (PTC-on).
Externí odkaz:
https://doaj.org/article/829a8aae5f3b47078ff904973b24c79e
Autor:
Xiyao Cheng, Rong Chen, Ting Zhou, Bailing Zhang, Zichun Li, Meng Gao, Yongqi Huang, Huili Liu, Zhengding Su
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-11 (2022)
Peptide fragments derived from the interfaces of protein-protein interactions (PPIs) provide useful templates for designing small molecule PPI inhibitors. Here, the authors utilize the multivalency of an MdmX-binding p53 peptide to develop a weak inh
Externí odkaz:
https://doaj.org/article/226c507ff9634f0693161615deb0f2ae
Autor:
Xin Li, Tian Chen, Fei Peng, Shikui Song, Jingpeng Yu, Douanla Njimeli Sidoine, Xiyao Cheng, Yongqi Huang, Yijun He, Zhengding Su
Publikováno v:
Microbial Cell Factories, Vol 20, Iss 1, Pp 1-15 (2021)
Abstract 4-Androstene-3,17-dione (4-AD), 1,4-androstadiene-3,17-dione (ADD) and 9α-hydroxyl-4-androstene-3,17-dione (9OH-AD), which are important starting compounds for the synthesis of steroidal medicines, can be biosynthetically transformed from p
Externí odkaz:
https://doaj.org/article/1ae1bd6405d64294b85a2ec11c50a548
Autor:
Hongwei Wang, Shikui Song, Fei Peng, Fei Yang, Tian Chen, Xin Li, Xiyao Cheng, Yijun He, Yongqi Huang, Zhengding Su
Publikováno v:
Microbial Cell Factories, Vol 19, Iss 1, Pp 1-19 (2020)
Abstract Mycobacterium neoaurum strains can transform phytosterols to 4-androstene-3,17-dione (4-AD), a key intermediate for the synthesis of advanced steroidal medicines. In this work, we presented the complete genome sequence of the M. neoaurum str
Externí odkaz:
https://doaj.org/article/81312d4450554934bccc8ccf1dbf0b07
Autor:
Chao Feng, Yinong Huang, Wangxiao He, Xiyao Cheng, Huili Liu, Yongqi Huang, Bohan Ma, Wei Zhang, Chongbing Liao, Weihui Wu, Yongping Shao, Dan Xu, Zhengding Su, Wuyuan Lu
Publikováno v:
ACS Central Science, Vol 5, Iss 7, Pp 1278-1288 (2019)
Externí odkaz:
https://doaj.org/article/7737023a44eb4fe28d07f6b765e5b703
Autor:
Jinkui Li, Lingya Zhang, Junwen Xiong, Xiyao Cheng, Yongqi Huang, Zhengding Su, Ming Yi, Sen Liu
Publikováno v:
Molecules, Vol 24, Iss 18, p 3351 (2019)
Polyamines are positively charged small molecules ubiquitously existing in all living organisms, and they are considered as one kind of the most ancient cellular components. The most common polyamines are spermidine, spermine, and their precursor put
Externí odkaz:
https://doaj.org/article/61cb237c4e1a46789b8eb7504db2525f
Publikováno v:
Journal of the Science of Food and Agriculture.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::07ce8a47629075636dbce237035d4a71
https://doi.org/10.1002/jsfa.12623
https://doi.org/10.1002/jsfa.12623