Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Xiwu Ouyang"'
Autor:
Lei Yao, Jun Li, Bo Jiang, Zeyu Zhang, Xinying Li, Xiwu Ouyang, Yao Xiao, Guodong Liu, Zhiming Wang, Gewen Zhang
Publikováno v:
Cell Death and Disease, Vol 14, Iss 4, Pp 1-13 (2023)
Abstract RNF2 is a RING domain-containing E3 ubiquitin ligase that mediate histone H2A mono-ubiquitination to repress gene transcription, but its expression patterns and molecular function in hepatocellular carcinoma (HCC) remain unclear. Herein, we
Externí odkaz:
https://doaj.org/article/2fc43dd41d794079ae7ec5cde6d278ac
Autor:
Guodong Liu, Xiwu Ouyang, Liansheng Gong, Lei Yao, Shiqing Liu, Jiarong Li, Qi Zhang, Yao Xiao
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 26, Iss , Pp 104-113 (2021)
Liver cancer is one of the most lethal malignant tumors in the world. The high recurrence and mortality rate make it urgent for scientists and clinicians to find new targets for better treatment of liver cancer. Here, we found that circ-PRKAR1B expre
Externí odkaz:
https://doaj.org/article/238b5c1673654c0f844265f611cde87c
Publikováno v:
Molecular Therapy: Oncolytics, Vol 23, Iss , Pp 65-81 (2021)
Isocitrate dehydrogenase (IDH) mutations increase (R)-2-hydroxyglutarate (R-2HG) production; however, functional mechanisms of R-2HG in regulating cholangiocarcinoma (CCA) development remain to be further investigated. We first applied the CRISPR-Cas
Externí odkaz:
https://doaj.org/article/2717652290ad4410902ed39d1182e716
Autor:
Xiwu Ouyang, Lemeng Feng, Lei Yao, Yao Xiao, Xianyu Hu, Gewen Zhang, Guodong Liu, Zhiming Wang
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 24, Iss , Pp 755-767 (2021)
The incidence and mortality of papillary thyroid cancer (PTC) have steadily increased. Although conventional therapies are very effective toward differentiated PTC patients, very limited therapeutic options are applicable to those patients with dista
Externí odkaz:
https://doaj.org/article/ecb52afc478e4b6d8144def1f3602423
Autor:
Yao Xiao, Lantao Peng, Hongjuan Xu, Ming Huang, Chao Yang, Guodong Liu, Xiwu Ouyang, Xiaoli Li, Yuanjing Wang, Langqing Sheng, Denggao Zhai, Ling Lin, Ling Liu, Gang Liu, Liansheng Gong
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Liver cancer is one of the most lethal malignant tumors in the world, and surgical resection is the main treatment for liver cancer. Liver failure due to insufficient residual liver volume is a fatal complication after hepatectomy. How to effectively
Externí odkaz:
https://doaj.org/article/811404e101b44ff6b8a6911fe526717f
Publikováno v:
Molecular Therapy: Oncolytics, Vol 23, Iss, Pp 65-81 (2021)
Molecular Therapy Oncolytics
Molecular Therapy Oncolytics
Isocitrate dehydrogenase (IDH) mutations increase (R)-2-hydroxyglutarate (R-2HG) production; however, functional mechanisms of R-2HG in regulating cholangiocarcinoma (CCA) development remain to be further investigated. We first applied the CRISPR-Cas
Publikováno v:
Genetic Testing and Molecular Biomarkers. 25:685-695
Background: Most cholangiocarcinoma (CCA) patients are diagnosed at an advanced stage of disease, and the postoperational recurrence rates are high in those undergoing resection. The lack of satisfying biomarkers for early diagnoses and effective tar
Autor:
Xiwu Ouyang, Lei Yao, Zhiming Wang, Xiao Yao, Gewen Zhang, Liu Shiqing, Liu Guodong, Lemeng Feng
Publikováno v:
Journal of Cancer
Hepatocellular carcinoma (HCC) is the most 5th commonly diagnosed and 2nd most lethal tumor in the world. The obvious gender advantage of HCC indicates that androgen receptor (AR) may play an important role in the tumor occurrence, develop and metast
Publikováno v:
Oncology Letters
Early studies have indicated that insulin-like growth factor II mRNA binding protein 3 (IGF2BP3/IMP3) may affect the progression of hepatocellular carcinoma (HCC); however, the detailed underlying mechanisms, particularly its linkage to tight junctio
Publikováno v:
Oncology Letters
Cadherin EGF LAG seven-pass G-type receptor 3 (CELSR3) has been reported to exhibit a cancer-specific pattern. The present study aimed to investigate the clinical value and functional role of CELSR3 in hepatocellular carcinoma (HCC), and determine th