Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Xiwu Hui"'
Autor:
Huandi Ding, Bing Yao, Lei Ci, Jing Feng, Pingkai Ouyang, Guoguang Chen, Xiwu Hui, Demin Zhou
Publikováno v:
Journal of Immunotherapy. 46:161-169
Autor:
Bing Yao, Xiao Gao, Mo Dan, Can Yuan, Xixin Hu, Zhaopeng Sun, Xiwu Hui, Boning Liu, Pingkai Ouyang, Guoguang Chen
Publikováno v:
The AAPS journal. 24(4)
The main objective of this work was to demonstrate which kind of payload is the suitable choice for antibody-drug conjugates directed to widely expressed tumor-associated antigen. Trop-2 is overexpressed in various solid tumors, but it is also presen
Autor:
Bing Yao, Di Zhang, Weirong Cao, Gaoqiang Yang, Wenbin Li, Xiwu Hui, Pingkai Ouyang, Guoguang Chen, Boning Liu
Publikováno v:
BioMed research international. 2022
The proposed biosimilar candidate needs to demonstrate biosimilarity with reference products, and the quality target product profile and biosimilarity assessment criteria are prerequisite, which should be based on extensive characterization of the re
Publikováno v:
Sheng wu gong cheng xue bao = Chinese journal of biotechnology. 36(4)
PEGylation is considered one of the most successful techniques to improve the characteristics of protein drugs including to increase the circulating half-life of proteins in blood and to decrease their immunogenicity and antigenicity. One known PEG m
Publikováno v:
Sheng wu gong cheng xue bao = Chinese journal of biotechnology. 34(4)
IFN-λ1 is a member of a new family of interferons called type Ⅲ IFNs with similar functions to type ⅠIFNs. Previously we obtained recombinant soluble human rhIFN-λ1 from Pichia pastoris. However, the hyper-glycosylation from P. pastoris brings
Publikováno v:
Cancer Letters. 311:141-151
Interferon (IFN)-λ1, as a newly identified IFN, interacts with the structurally unique IFN-λ1 receptor complex and exhibits antiviral and antiproliferation effects. The major focus of our work was to study the antitumor activities of recombinant hu
Autor:
Qinshan Li, Bingren Huang, Xia Yang, Deng Chen, Junwen Zhang, Zhenzhen Fan, Xiwu Hui, Shuo Tian, Xiaoli Ma, Hong Chen
Publikováno v:
FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 28(8)
Hepatocellular carcinoma (HCC) is a common cancer associated with chronic hepatitis B virus (HBV) infection. Conventional interferon-α (IFN-α) and pegylated IFNs (PEG-IFNs) approved for chronic HBV infection treatment can reduce the risk of HCC but
Publikováno v:
Journal of cellular biochemistry. 113(11)
IFNλR1 is a member of the class II cytokine receptor family, and it associates with IL-10R2 to form a functional receptor complex, IFNλR. This receptor complex transduces signals from IFNλs (IFNλ1, IFNλ2, and IFNλ3), promoting antiviral and ant
Autor:
Shuo Tian, Xiwu Hui, Zhenzhen Fan, Qinshan Li, Junwen Zhang, Xia Yang, Xiaoli Ma, Bingren Huang, Deng Chen, Hong Chen
Publikováno v:
FASEB Journal; Aug2014, Vol. 28 Issue 8, p3528-3539, 12p