Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Xiwen Gu"'
Autor:
Zhiyang Xu, Kaixiang Zhou, Zhenni Wang, Yang Liu, Xingguo Wang, Tian Gao, Fanfan Xie, Qing Yuan, Xiwen Gu, Shujuan Liu, Jinliang Xing
Publikováno v:
Experimental and Molecular Medicine, Vol 55, Iss 7, Pp 1388-1398 (2023)
Abstract Ovarian cancer (OC) is the most lethal gynecologic tumor and is characterized by a high rate of metastasis. Challenges in accurately delineating the metastatic pattern have greatly restricted the improvement of treatment in OC patients. An i
Externí odkaz:
https://doaj.org/article/55357745af34406c8dfe4c7a699b5918
Autor:
Fanfan Xie, Wenjie Guo, Xingguo Wang, Kaixiang Zhou, Shanshan Guo, Yang Liu, Tianlei Sun, Shengjing Li, Zhiyang Xu, Qing Yuan, Huanqin Zhang, Xiwen Gu, Jinliang Xing, Shujuan Liu
Publikováno v:
Clinical and Translational Medicine, Vol 14, Iss 1, Pp n/a-n/a (2024)
Abstract Background Epithelial ovarian cancer (EOC) heavily relies on oxidative phosphorylation (OXPHOS) and exhibits distinct mitochondrial metabolic reprogramming. Up to now, the evolutionary pattern of somatic mitochondrial DNA (mtDNA) mutations i
Externí odkaz:
https://doaj.org/article/9c00821e9a6d405780258f0884d43413
Autor:
Wenjie Guo, Yang Liu, Liping Su, Shanshan Guo, Fanfan Xie, Xiaoying Ji, Kaixiang Zhou, Xu Guo, Xiwen Gu, Jinliang Xing
Publikováno v:
Molecular Oncology, Vol 17, Iss 5, Pp 857-871 (2023)
Mitochondrial DNA (mtDNA) somatic mutations play important roles in the initiation and progression of cancer. Although next‐generation sequencing (NGS) of paired tumor and control samples has become a common practice to identify tumor‐specific mt
Externí odkaz:
https://doaj.org/article/4d36e3c9b71841aeb4d343aaa71d3f52
Autor:
Xiaoying Ji, Wenjie Guo, Xiwen Gu, Shanshan Guo, Kaixiang Zhou, Liping Su, Qing Yuan, Yang Liu, Xu Guo, Qichao Huang, Jinliang Xing
Publikováno v:
EBioMedicine, Vol 80, Iss , Pp 104058- (2022)
Summary: Background: Mitochondrial DNA (mtDNA) mutations alter mitochondrial function in oxidative metabolism and play an important role in tumorigenesis. A series of studies have demonstrated that the mtDNA control region (mtCTR), which is essential
Externí odkaz:
https://doaj.org/article/e33b749c52fb4a809ef71d43652c7e33
Autor:
Shanshan Guo, Kaixiang Zhou, Qing Yuan, Liping Su, Yang Liu, Xiaoying Ji, Xiwen Gu, Xu Guo, Jinliang Xing
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 23, Iss , Pp 232-243 (2021)
Next-generation sequencing technology has been commonly applied to detect mitochondrial DNA (mtDNA) mutations, which are reported to be strongly associated with cancers. However, several key challenges still exist regarding bioinformatics analysis of
Externí odkaz:
https://doaj.org/article/458d40d7cd16408b8840cd90cbe93944
Autor:
Yang Liu, Kaixiang Zhou, Shanshan Guo, Yang Wang, Xiaoying Ji, Qing Yuan, Liping Su, Xu Guo, Xiwen Gu, Jinliang Xing
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 23, Iss , Pp 657-666 (2021)
Mitochondrial DNA (mtDNA) mutations are closely implicated in the pathogenesis of multiple cancers, making circulating cell-free mtDNA (ccf-mtDNA) as a potential non-invasive tumor biomarker. However, an effective approach to comprehensively profile
Externí odkaz:
https://doaj.org/article/de6fae0289574cdc93bea6904612815a
Publikováno v:
Sensors, Vol 23, Iss 6, p 3130 (2023)
The fault diagnosis of rolling bearings is critical for the reliability assurance of mechanical systems. The operating speeds of the rolling bearings in industrial applications are usually time-varying, and the monitoring data available are difficult
Externí odkaz:
https://doaj.org/article/6f0fd12d985c42e8a194f3a015e55b15
Publikováno v:
FEBS Open Bio, Vol 10, Iss 9, Pp 1782-1792 (2020)
Activation‐induced cytidine deaminase (AID) initiates somatic hypermutation and class switch recombination of immunoglobulin genes in B cells, whereas off‐targeted AID activity contributes to oncogenic mutations and chromosomal translocations ass
Externí odkaz:
https://doaj.org/article/7179933ddb07459a8111ceabc93ffbae
Publikováno v:
Applied Sciences, Vol 8, Iss 10, p 1796 (2018)
Cylindrical structures play an important role in industrial fields. The surface crack is a typical defect in the cylindrical structures. Non-destructive surface crack detection of these structures is critical to the safe operation of the equipment. I
Externí odkaz:
https://doaj.org/article/74aa96a33fc340d8be74224eb6d9f080
Autor:
Wenjie, Guo, Yang, Liu, Xiaoying, Ji, Shanshan, Guo, Fanfan, Xie, Yanxing, Chen, Kaixiang, Zhou, Huanqin, Zhang, Fan, Peng, Dan, Wu, Zhenni, Wang, Xu, Guo, Qi, Zhao, Xiwen, Gu, Jinliang, Xing
Publikováno v:
Theranostics. 13:324-338
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cbf619bf5f69fac3f8a921ee741660b1
https://doi.org/10.7150/thno.78718
https://doi.org/10.7150/thno.78718