Zobrazeno 1 - 10
of 57
pro vyhledávání: '"Xiuyun Hou"'
Publikováno v:
The American Journal of Pathology. 187:2095-2101
The arteriovenous fistula is the preferred type of hemodialysis vascular access for patients with end-stage renal disease, but a high proportion of newly created fistulas fail to mature for use. Stenosis caused by neointimal hyperplasia often is pres
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40e2c6f1669bb603d705129b31fd2518
https://doi.org/10.1016/j.ajpath.2017.05.006
https://doi.org/10.1016/j.ajpath.2017.05.006
Autor:
Richard A. Cohen, Xiuyun Hou, Di Shao, Markus Bachschmid, Hemant K. Roy, Francesca Seta, Jessica L. Fry, Michelle T. Long, Jingyan Han, Jessica B. Behring, Reiko Matsui
Publikováno v:
Antioxidants & Redox Signaling. 27:313-327
Aims: Nonalcoholic fatty liver (NAFL) is a common liver disease associated with metabolic syndrome, obesity, and diabetes that is rising in prevalence worldwide. Various molecular perturbations of key regulators and enzymes in hepatic lipid metabolis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e26dfbc40a0533b7295a2f76249b110
https://doi.org/10.1089/ars.2016.6716
https://doi.org/10.1089/ars.2016.6716
Autor:
Benjamin D. Humphreys, Tetsuro Kusaba, Anusha Aravamudhan, Deepika Rangarajan, Omar H. Maarouf, Victor Zhang, Jeremy Welborn, Xiuyun Hou, Rafael Kramann, Daniel Gauvin
Publikováno v:
Journal of the American Society of Nephrology. 27:781-790
AKI with incomplete epithelial repair is a major contributor to CKD characterized by tubulointerstitial fibrosis. Injury-induced epithelial secretion of profibrotic factors is hypothesized to underlie this link, but the identity of these factors and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0264f6c83e8c869e6de6fb8b758f0d8
https://doi.org/10.1681/asn.2014121188
https://doi.org/10.1681/asn.2014121188
Autor:
Di Shao, David R. Pimentel, Jessica L. Fry, Markus Bachschmid, Richard A. Cohen, Reiko Matsui, Jingyan Han, Xiuyun Hou
Publikováno v:
Journal of Biological Chemistry. 289:7293-7306
Sirtuin-1 (SirT1), a member of the NAD(+)-dependent class III histone deacetylase family, is inactivated in vitro by oxidation of critical cysteine thiols. In a model of metabolic syndrome, SirT1 activation attenuated apoptosis of hepatocytes and imp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d9317017d3969b4cbb8444cfee3453e
https://doi.org/10.1074/jbc.m113.520403
https://doi.org/10.1074/jbc.m113.520403
Autor:
Stacy S. Kirkpatrick, Feng Liu, Ming-Hui Zou, Chaomei Shi, Mitchell H. Goldman, Xiuyun Hou, Richard A. Cohen
Publikováno v:
Journal of Biological Chemistry. 294:18016
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8dbfa81fc35866639a1249f07a10d381
https://doi.org/10.1074/jbc.w119.011600
https://doi.org/10.1074/jbc.w119.011600
Autor:
Deborah A. Siwik, Eric H. Weiss, Jessica Edgecomb, Ion A. Hobai, Xiuyun Hou, Antonis A. Armoundas, Peter Brouckaert, Richard A. Cohen, Alok R. Khandelwal, Emmanuel S. Buys, Justin C. Morse, Wilson S. Colucci
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 305:H1189-H1200
The goal of this study was to identify the cellular mechanisms responsible for cardiac dysfunction in endotoxemic mice. We aimed to differentiate the roles of cGMP [produced by soluble guanylyl cyclase (sGC)] versus oxidative posttranslational modifi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9c043fed82d6f6c474fc0fe55f48fe5
https://doi.org/10.1152/ajpheart.00392.2012
https://doi.org/10.1152/ajpheart.00392.2012
Autor:
Noriyuki Ouchi, Deborah A. Siwik, Wilson S. Colucci, Xiuyun Hou, T.J. Verbeuren, Fuzhong Qin, Lei Wang, Kenneth Walsh, Akiko Higuchi, Timothy D. Calamaras, Edward J. Miller, Robert M. Weisbrod, Vivian H. Tu, Ivan Luptak, Richard A. Cohen
Publikováno v:
Circulation. 125:1757-1764
Background— Diet-induced obesity is associated with metabolic heart disease characterized by left ventricular hypertrophy and diastolic dysfunction. Polyphenols such as resveratrol and the synthetic flavonoid derivative S17834 exert beneficial syst
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4bcd00971eca681c67077dfa56b20a45
https://doi.org/10.1161/circulationaha.111.067801
https://doi.org/10.1161/circulationaha.111.067801
Publikováno v:
Hypertension. 58:310-316
The development of cardiovascular fibrosis is associated with chronic inflammation, where activation of nuclear factor κB (NF-κB) signaling may play a critical role. NF-κB activation is tightly regulated by the cellular inhibitor of κB (IκB) fam
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52169b5daa94f2b54d50e876f7b97bb2
https://doi.org/10.1161/hypertensionaha.111.172031
https://doi.org/10.1161/hypertensionaha.111.172031
Publikováno v:
Biochemical and Biophysical Research Communications. 410:543-548
Angiotensin II is implicated in cardiovascular diseases, which is associated with a role in increasing vascular inflammation. The present study investigated how angiotensin II modulates vascular inflammatory signaling and expression of inducible nitr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d929de76075b0ace7c00d5476fa6aa0c
https://doi.org/10.1016/j.bbrc.2011.06.021
https://doi.org/10.1016/j.bbrc.2011.06.021
Autor:
David H. Perlman, Richard A. Cohen, Mark E. McComb, Rebecca Zee, Markus Bachschmid, Joseph R. Burgoyne, Xiuyun Hou, Chris B. Yoo, Catherine E. Costello, David R. Pimentel
Publikováno v:
Antioxidants & Redox Signaling. 13:1023-1032
Sirtuin-1 (SIRT1) is an NAD+-dependent protein deacetylase that is sensitive to oxidative signals. Our purpose was to determine whether SIRT1 activity is sensitive to the low molecular weight nitrosothiol, S-nitrosoglutathione (GSNO), which can trans
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9129f6c425a7cbd5f1dd68da23b1cc81
https://doi.org/10.1089/ars.2010.3251
https://doi.org/10.1089/ars.2010.3251