Zobrazeno 1 - 10
of 311
pro vyhledávání: '"Xiuyun, Sun"'
Publikováno v:
Advanced Science, Vol 11, Iss 25, Pp n/a-n/a (2024)
Abstract Natural products, while valuable for drug discovery, encounter limitations like uncertainty in targets and toxicity. As an important active ingredient in traditional Chinese medicine, celastrol exhibits a wide range of biological activities,
Externí odkaz:
https://doaj.org/article/14999b23d87c480396e19ce526a3a6f6
Publikováno v:
Acta Materia Medica, Vol 2, Iss 4, Pp 409-429 (2023)
The field of epigenetics pertains to alterations in gene function that are inherited without changes in the DNA sequence, including histone modifications, post-translational modifications of amino acids, and covalent modifications of DNA bases. These
Externí odkaz:
https://doaj.org/article/3d1feeb845654bdf918c1fe5905151fa
Autor:
Chao Zhang, Yugang Song, Xiuyun Sun, Qianlong Liu, Zhen Li, Shenyi Yin, Jianzhong Jeff Xi, Xin Zhai, Yu Rao
Publikováno v:
Acta Materia Medica, Vol 2, Iss 4, Pp 400-408 (2023)
Tylophorine has diverse biological activities; however, the stability, solubility, and central nervous system toxicity have severely limited use of tylophorine. The gem -dimethyl group is an organic chemistry functional group that consists of two met
Externí odkaz:
https://doaj.org/article/49951affb9814c97b921a267fb5d449f
Autor:
Xin Yan, Yiyuan Yao, Chengming Xiao, Hao Zhang, Jia Xie, Shuai Zhang, Junwen Qi, Zhigao Zhu, Xiuyun Sun, Jiansheng Li
Publikováno v:
Molecules, Vol 29, Iss 17, p 4059 (2024)
Catalytic performance decline is a general issue when shaping fine powder into macroscale catalysts (e.g., beads, fiber, pellets). To address this challenge, a phenolic resin-assisted strategy was proposed to prepare porous Co/N carbon beads (ZACBs)
Externí odkaz:
https://doaj.org/article/c988b520f3fa453b9db2e2c40ee29243
Autor:
Shihao Song, Shuo Zhao, Xiuyun Sun, Lili Meng, Zijie Wang, Huihui Tan, Jingyun Liu, Min Zhang, Yinyue Deng
Publikováno v:
Virulence, Vol 14, Iss 1 (2023)
ABSTRACTCandida albicans is an important opportunistic pathogenic fungus that frequently causes serious systemic infection in humans. Due to the vital roles of biofilm formation and the yeast-to-hypha transition in the infection process, we have sele
Externí odkaz:
https://doaj.org/article/f38c04fd3e174b3f81e3b8251fcc408d
Autor:
Junjun Huang, Shihao Song, Shuo Zhao, Xiuyun Sun, Zijie Wang, Xiaorong Huang, Qing Xiao, Yinyue Deng
Publikováno v:
Microbial Biotechnology, Vol 16, Iss 1, Pp 116-127 (2023)
Abstract Candida albicans is an important human fungal pathogen. Our previous study disclosed that aryloxy‐phenylpiperazine skeleton was a promising molecule to suppress C. albicans virulence by inhibiting hypha formation and biofilm formation. In
Externí odkaz:
https://doaj.org/article/61e4d8726d594de8b91020a9820f7fb0
Autor:
Ming He, Chaoguo Cao, Zhihao Ni, Yongbo Liu, Peilu Song, Shuang Hao, Yuna He, Xiuyun Sun, Yu Rao
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 7, Iss 1, Pp 1-64 (2022)
Abstract PROteolysis TArgeting Chimeras (PROTACs) technology is a new protein-degradation strategy that has emerged in recent years. It uses bifunctional small molecules to induce the ubiquitination and degradation of target proteins through the ubiq
Externí odkaz:
https://doaj.org/article/6610e26ab97a42a3b375b9f85e9f863c
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 7, Iss 1, Pp 1-4 (2022)
Externí odkaz:
https://doaj.org/article/8e699aa05d2944ea9316217c9d98443e
Publikováno v:
Microbiology Spectrum, Vol 10, Iss 4 (2022)
ABSTRACT Burkholderia cenocepacia is a human opportunistic pathogen that mostly employs two types of quorum-sensing (QS) systems to regulate its various biological functions and pathogenicity: the cis-2-dodecenoic acid (BDSF) system and the N-acyl ho
Externí odkaz:
https://doaj.org/article/62f40bccea1b45c2959da451482a429e
Publikováno v:
Microbial Biotechnology, Vol 14, Iss 2, Pp 430-443 (2021)
Summary Candida albicans is a common human fungal pathogen. The previous study revealed that quinone compounds showed antimicrobial activity against C. albicans by inhibiting cell growth. However, it was unclear whether quinones have other antifungal
Externí odkaz:
https://doaj.org/article/127444813d5d4b52a5202273da6d169f