Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Xiuying Wen"'
Publikováno v:
Frontiers in Public Health, Vol 12 (2024)
BackgroundAddressing the long-term physical and mental health impacts of adverse childhood experiences (ACEs) remains a significant public health challenge. Additionally, ACEs can contribute to intergenerational transmission, affecting future generat
Externí odkaz:
https://doaj.org/article/7f7332c91d0542a0884162b10ef6c09f
Publikováno v:
BMC Complementary Medicine and Therapies, Vol 20, Iss 1, Pp 1-12 (2020)
Abstract Background As a compound Chinese medicine, Zhenqing Recipe (ZQR) has been shown to ameliorate hyperglycemia, hyperlipidemia, fatty liver and insulin resistance in patients with diabetes and diabetic rats. In this paper, we further examined t
Externí odkaz:
https://doaj.org/article/1471a750307546c5b6034c75bc2bf4fb
Publikováno v:
Frontiers in Endocrinology, Vol 11 (2020)
The regulation of hepatic gluconeogenesis is of great significance to improve insulin resistance and benefit diabetes therapy. cAMP-Regulated Transcriptional Co-activator 2 (CRTC2) plays a key role in regulating hepatic gluconeogenesis through contro
Externí odkaz:
https://doaj.org/article/27280474d7464695ab5b44320b3f586a
Publikováno v:
PLoS ONE, Vol 14, Iss 6, p e0210930 (2019)
AimIn this study, we investigated the role and mechanism of Salt-induced kinase 1 (SIK1) in regulation of hepatic glucose and lipid metabolism in a high-fat food (HFD) and streptozocin (STZ)-induced type 2 diabetes mellitus (T2DM) rat model.MethodsA
Externí odkaz:
https://doaj.org/article/cdb0c57fbc31480eb13bf8d208a9a992
Publikováno v:
Quality Assurance and Safety of Crops & Foods. 14:40-46
Diabetic nephropathy, a chronic inflammatory disease, is characterized by hyperglycemia-stimulated pyroptosis of renal tubular epithelial cells. Gambogic acid, a primary component of gamboge resin, exerts detoxification, antioxidant, anticancer, anti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a55e01e93ace1fd3a06d60d7e4c7d06e
https://doi.org/10.15586/qas.v14i2.990
https://doi.org/10.15586/qas.v14i2.990
Publikováno v:
Tropical Journal of Pharmaceutical Research. 19:1227-1232
Purpose: To determine the antioxidant and anti-diabetic potential of a natural flavonoid, caffeic acid in a streptozotocin-induced diabetic rat model.Methods: Experimental diabetes was induced in Wistar rats using streptozotocin injection. Caffeic ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1d638940c080fefabfca72183eeeba1c
https://doi.org/10.4314/tjpr.v19i6.17
https://doi.org/10.4314/tjpr.v19i6.17
Zhenqing recipe relieves diabetic nephropathy through the SIK1/SREBP-1c axis in type 2 diabetic rats
Publikováno v:
Am J Transl Res
Background: Salt-inducible kinase 1 (SIK1) plays an important role in lipid metabolism, which inhibits lipid synthesis by directly phosphorylating multiple serine residue sites of sterol regulatory element-binding protein 1c (SREBP-1c). This study ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::47041bb55bfa0768f507006012625546
https://pubmed.ncbi.nlm.nih.gov/35035716
https://pubmed.ncbi.nlm.nih.gov/35035716
Publikováno v:
Frontiers in Endocrinology, Vol 11 (2020)
The regulation of hepatic gluconeogenesis is of great significance to improve insulin resistance and benefit diabetes therapy. cAMP-Regulated Transcriptional Co-activator 2 (CRTC2) plays a key role in regulating hepatic gluconeogenesis through contro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3824e46dc5e5022862cb544af0fb1368
https://doi.org/10.3389/fendo.2020.00580
https://doi.org/10.3389/fendo.2020.00580
Autor:
Chang Wang, Liang Xiong, Xiuying Wen, Yue Zhang, Ming-Wang Xu, Ningxu Li, Jiahui Fu, Hiroshi Takemori
Publikováno v:
Life Sciences. 173:107-115
Aims To investigate the roles of salt inducible kinase (SIK1) in high glucose-induced triglyceride accumulation in human hepatoma HepG2 cells as well as in the molecular mechanism by which metformin, a drug to treat diabetes, suppresses high glucose-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5eec06ab1fdc775e17230898af6cb31
https://doi.org/10.1016/j.lfs.2017.02.001
https://doi.org/10.1016/j.lfs.2017.02.001
Additional file 1. ARRIVE checklist.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51431df8c9e0938a1d5c1d76f4775f5c
