Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Xiuye Cao"'
Autor:
Wenbin Zhong, Weize Lin, Yingjie Yang, Dan Chen, Xiuye Cao, Mengyang Xu, Guoping Pan, Huanzhao Chen, Jie Zheng, Xiaoqin Feng, Li hua Yang, Chaofeng Lai, Vesa M. Olkkonen, Jun Xu, Shuzhong Cui, Daoguang Yan
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022)
The oxysterol-binding protein-related protein 4 (ORP4L) is expressed in T-cell acute lymphoblastic leukemia and is required for leukemogenesis. Here the authors show that ORP4L orchestrates the transport of the phospholipid PI(4)P from Golgi to the p
Externí odkaz:
https://doaj.org/article/89563adda1a945dcab83f9f04ad0cae7
Autor:
Wenbin Zhong, Mengyang Xu, Chanjuan Li, Biying Zhu, Xiuye Cao, Dan Li, Huanzhao Chen, Chunxiu Hu, Rong Li, Chengwei Luo, Guoping Pan, Wenqiang Zhang, Chaofeng Lai, Tong Wang, Xin Du, Hong Chen, Guowang Xu, Vesa M. Olkkonen, Pingsheng Lei, Jun Xu, Daoguang Yan
Publikováno v:
Cell Reports, Vol 26, Iss 8, Pp 2166-2177.e9 (2019)
Summary: Leukemia stem cells (LSCs) are a rare subpopulation of abnormal hematopoietic stem cells (HSCs) that propagates leukemia and are responsible for the high frequency of relapse in therapies. Detailed insights into LSCs’ survival will facilit
Externí odkaz:
https://doaj.org/article/b4cbfae4d4f5492d9716b7d066b1373f
Autor:
Daoguang Yan, Yu Huang, Wenbin Zhong, Xiuye Cao, Guoping Pan, Meng-Yang Xu, Qun Niu, Qing Yi, Xiaoqin Feng, Mingchuan Li
Publikováno v:
Blood. 139:1052-1065
Human T-cell leukemia virus 1 (HTLV-1) causes adult T-cell leukemia (ATL), but the mechanism underlying its initiation remains elusive. In this study, ORP4L was expressed in ATL cells but not in normal T-cells. ORP4L ablation completely blocked T-cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d51da57051e6de7c93638950da36898f
https://doi.org/10.1182/blood.2021013579
https://doi.org/10.1182/blood.2021013579
Autor:
Vesa M. Olkkonen, Xiuye Cao, Jun Xu, Wenbin Zhong, Daoguang Yan, Shannai Li, Dan Li, Biying Zhu, Huihao Zhou, Meng-Yang Xu
Publikováno v:
The Journal of Immunology. 204:1134-1145
Phospholipase C (PLC) isoforms play central roles in signaling cascades by cleaving PIP2 into the second messengers IP3 and DAG. In this study, to our knowledge, we uncover that ORP5L interacts physically with PLCγ1 in T cells, extracts PIP2 from th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d1ae430ba817fac29d87ecbfe1ce087f
https://doi.org/10.4049/jimmunol.1900671
https://doi.org/10.4049/jimmunol.1900671
Autor:
Biying Zhu, Wenbin Zhong, Xiuye Cao, Guoping Pan, Mengyang Xu, Jie Zheng, Huanzhao Chen, Xiaoqin Feng, Chengwei Luo, Chen Lu, Jie Xiao, Weize Lin, Chaofeng Lai, Mingchuan Li, Xin Du, Qing Yi, Daoguang Yan
Publikováno v:
Science translational medicine. 14(629)
Leukemia stem cells (LSCs) propagate leukemia and are responsible for the high frequency of relapse of treated patients. The ability to target LSCs remains elusive, indicating a need to understand the underlying mechanism of LSC formation. Here, we r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8090207388d8d9726400012426f9fe23
https://pubmed.ncbi.nlm.nih.gov/35080912
https://pubmed.ncbi.nlm.nih.gov/35080912
Autor:
Guoping Pan, Weize Lin, Xiuye Cao, Vesa M. Olkkonen, Meng-Yang Xu, Daoguang Yan, Peipei Xie, Shiqian Li, Wenbin Zhong, Jun Xu, Dan Li, Yong Tang, Jianuo Chen
Publikováno v:
The FASEB Journal. 33:13852-13865
Oxysterol-binding protein–related protein (ORP) 4L acts as a scaffold protein assembling CD3-e, G-αq/11, and PLC-β3 into a complex at the plasma membrane that mediates inositol (1,4,5)-trisphosphat...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c40d0034be68ede0f909ca1f439bea51
https://doi.org/10.1096/fj.201900933rr
https://doi.org/10.1096/fj.201900933rr
Autor:
Chaofeng Lai, Chanjuan Li, Jun Xu, Pingsheng Lei, Rong Li, Guowang Xu, Hong Chen, Chengwei Luo, Daoguang Yan, Wenbin Zhong, Wenqiang Zhang, Chunxiu Hu, Biying Zhu, Xin Du, Huanzhao Chen, Xiuye Cao, Dan Li, Vesa M. Olkkonen, Guoping Pan, Tong Wang, Meng-Yang Xu
Publikováno v:
Cell Reports, Vol 26, Iss 8, Pp 2166-2177.e9 (2019)
Summary: Leukemia stem cells (LSCs) are a rare subpopulation of abnormal hematopoietic stem cells (HSCs) that propagates leukemia and are responsible for the high frequency of relapse in therapies. Detailed insights into LSCs’ survival will facilit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7348eea800a0465decc90cbafc521e96
http://www.sciencedirect.com/science/article/pii/S2211124719301111
http://www.sciencedirect.com/science/article/pii/S2211124719301111
Autor:
Shiqian Li, Bart Staels, Jun Xu, Wenbin Zhong, Lin Wang, Guoping Pan, Jiwei Li, Daoguang Yan, Hongling Ma, Meng-Yang Xu, Jingsong Ou, Xiuye Cao, Vesa M. Olkkonen, Chaowen Li, Biying Zhu
Publikováno v:
Circulation Research. 119:1296-1312
Rationale: Macrophage survival within the arterial wall is a central factor contributing to atherogenesis. Oxysterols, major components of oxidized low-density lipoprotein, exert cytotoxic effects on macrophages. Objective: To determine whether oxyst
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c5549f954eb28f33d8b5ac325dbe9efc
https://doi.org/10.1161/circresaha.116.309603
https://doi.org/10.1161/circresaha.116.309603
Autor:
Xiuye, Cao, Jianuo, Chen, Dan, Li, Peipei, Xie, Mengyang, Xu, Weize, Lin, Shiqian, Li, Guoping, Pan, Yong, Tang, Jun, Xu, Vesa M, Olkkonen, Daoguang, Yan, Wenbin, Zhong
Publikováno v:
FASEB journal : official publication of the Federation of American Societies for Experimental BiologyREFERENCES. 33(12)
Oxysterol-binding protein-related protein (ORP) 4L acts as a scaffold protein assembling CD3-ε, G-α
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::78cbefaabb06ff6f9e0866dd12b9372a
https://pubmed.ncbi.nlm.nih.gov/31648575
https://pubmed.ncbi.nlm.nih.gov/31648575
Autor:
Mengyang, Xu, Biying, Zhu, Xiuye, Cao, Shannai, Li, Dan, Li, Huihao, Zhou, Vesa M, Olkkonen, Wenbin, Zhong, Jun, Xu, Daoguang, Yan
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 204(5)
Phospholipase C (PLC) isoforms play central roles in signaling cascades by cleaving PIP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::52ef7a5ebdf0724c0a0019c13313a7e9
https://pubmed.ncbi.nlm.nih.gov/31953353
https://pubmed.ncbi.nlm.nih.gov/31953353