Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Xiushan Yin"'
Autor:
Qinyao Zhu, Xiaofang He, Junhua Liu, Heming Wang, Xiaojiao Shan, Guangqi Song, Luo Zhang, Yicheng Zhao, Xiushan Yin
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-9 (2024)
Abstract Chimeric antigen receptor (CAR) T-cell therapies have shown remarkable results in patients with hematological malignancies. However, their success in treating solid tumors has been limited. As an alternative candidate for the CAR therapy, CA
Externí odkaz:
https://doaj.org/article/693a32daa084493b8e5ccdde45323b2b
Autor:
Lili Guan, Shanshan Wu, Qinyao Zhu, Xiaofang He, Xuelong Li, Guangqi Song, Luo Zhang, Xiushan Yin
Publikováno v:
Biochemistry and Biophysics Reports, Vol 39, Iss , Pp 101741- (2024)
Chimeric antigen receptor (CAR)-modified macrophages are a promising treatment for solid tumor. So far the potential effects of CAR-M cell therapy have rarely been investigated in hepatocellular carcinoma (HCC). Glypican-3 (GPC3) is a biomarker for a
Externí odkaz:
https://doaj.org/article/67c9f07ed25d48ad97605b63b30442fd
Publikováno v:
STAR Protocols, Vol 5, Iss 4, Pp 103350- (2024)
Summary: Human-derived macrophages are notoriously difficult to infect with HIV-1-based lentiviruses, posing a limitation to the advancement of chimeric antigen receptor macrophage (CAR-M) therapy. Here, we present a protocol for generating human chi
Externí odkaz:
https://doaj.org/article/7d057147f1d84941a7fbb98e27ef4d17
Publikováno v:
Heliyon, Vol 9, Iss 12, Pp e21886- (2023)
Genetically modified macrophage infusion has been proven to be a novel treatment for cancer. One of the most important processes in macrophage-based therapy is the efficient transfer of genes. HIV-1-derived lentiviruses were widely used as delivery v
Externí odkaz:
https://doaj.org/article/223f711759734faca9e830a1e36f1f12
Autor:
Huiying Liu, Cuiping Yang, Yun Gao, Xueli Zhang, Min Wang, Xinting Yu, Weidong Wang, Lixin Xie, Ping Tang, Xiushan Yin, Changqing Bai, Luo Zhang
Publikováno v:
Bioengineering & Translational Medicine, Vol 8, Iss 5, Pp n/a-n/a (2023)
Abstract Idiopathic pulmonary fibrosis (IPF) is a fatal interstitial lung disease characterized by chronic, progressive, and fibrotic lung injury. Although remarkable progress has been made toward understanding the pathogenesis of PF, finding more ef
Externí odkaz:
https://doaj.org/article/bbc09e3ca29a48808c1c18f9965cd511
Publikováno v:
Viruses, Vol 16, Iss 1, p 65 (2023)
Preventing the spread of SARS-CoV-2 and its variants is crucial in the fight against COVID-19. Inhibition of the main protease (Mpro) of SARS-CoV-2 is the key to disrupting viral replication, making Mpro a promising target for therapy. PF-07321332 an
Externí odkaz:
https://doaj.org/article/8f5787b852e54caca799bc2f4a2500f8
Publikováno v:
Fungal Biology and Biotechnology, Vol 8, Iss 1, Pp 1-9 (2021)
Abstract Background Sclerotium rolfsii is a potent producer of many secondary metabolites, one of which like scleroglucan is an exopolysaccharide (EPS) appreciated as a multipurpose compound applicable in many industrial fields. Results Aspartate tra
Externí odkaz:
https://doaj.org/article/f985c3932f6d4b4db534fbc98bd3d48e
Publikováno v:
Stem Cell Research & Therapy, Vol 12, Iss 1, Pp 1-13 (2021)
Abstract Background Age-related bone loss plays a vital role in the development of osteoporosis and osteoporotic fracture. Bone marrow stromal cell (BMSC) senescence is highly associated with osteoporosis and limits the application of BMSCs in regene
Externí odkaz:
https://doaj.org/article/4dd85b94a1934130b0b0495c1948d295
Autor:
Alisa Alekseenko, Donal Barrett, Yerma Pareja-Sanchez, Rebecca J. Howard, Emilia Strandback, Henry Ampah-Korsah, Urška Rovšnik, Silvia Zuniga-Veliz, Alexander Klenov, Jayshna Malloo, Shenglong Ye, Xiyang Liu, Björn Reinius, Simon J. Elsässer, Tomas Nyman, Gustaf Sandh, Xiushan Yin, Vicent Pelechano
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract RT-LAMP detection of SARS-CoV-2 has been shown to be a valuable approach to scale up COVID-19 diagnostics and thus contribute to limiting the spread of the disease. Here we present the optimization of highly cost-effective in-house produced
Externí odkaz:
https://doaj.org/article/1f27a366d4e94aed943f786f5264f7a0
Publikováno v:
Stem Cells International, Vol 2022 (2022)
The chronic liver diseases will slowly develop into liver fibrosis, cirrhosis, and even liver cancer if no proper control is performed with high efficiency. Up to now, the most effective treatment for end-stage liver diseases is liver transplantation
Externí odkaz:
https://doaj.org/article/028d960dd26c4715adcc2e205966bb7f