Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Xiuqun Zou"'
Autor:
Xiuqun Zou, Li Ma, Yihong Zhang, Qun Zhang, Chu Xu, Dan Zhang, Yimin Chu, Jie Zhang, Mengying Li, Hui Zhang, Jiamin Wang, Chicheng Peng, Gang Wei, Yingjie Wu, Zhaoyuan Hou, Hao Jia
Publikováno v:
Cell Death and Disease, Vol 14, Iss 6, Pp 1-15 (2023)
Abstract The transcriptional repressor Snail induces EMT during embryonic development and tumor metastasis. Growing evidence indicates that Snail functions as a trans-activator to induce gene expression; however, the underlying mechanism remains elus
Externí odkaz:
https://doaj.org/article/46f849ba008241049837ec6b27461ba8
Autor:
Dan Zhang, Yihong Zhang, Xiuqun Zou, Mengying Li, Hui Zhang, Yaning Du, Jiamin Wang, Chicheng Peng, Chunyan Dong, Zhaoyuan Hou
Publikováno v:
Cell Death and Disease, Vol 14, Iss 4, Pp 1-12 (2023)
Abstract Snail is a denoted transcriptional repressor that plays key roles in epithelial-mesenchymal transition (EMT) and metastasis. Lately, a plethora of genes can be induced by stable expression of Snail in multiple cell lines. However, the biolog
Externí odkaz:
https://doaj.org/article/0a09993791aa449e83431d9c2abb87dd
Autor:
Qun Zhang, Yihong Zhang, Jie Zhang, Dan Zhang, Mengying Li, Han Yan, Hui Zhang, Liwei Song, Jiamin Wang, Zhaoyuan Hou, Yunhai Yang, Xiuqun Zou
Publikováno v:
Cells, Vol 10, Iss 12, p 3593 (2021)
p66α is a GATA zinc finger domain-containing transcription factor that has been shown to be essential for gene silencing by participating in the NuRD complex. Several studies have suggested that p66α is a risk gene for a wide spectrum of diseases s
Externí odkaz:
https://doaj.org/article/8c12ed8d0e164c968ff7e1869b24bdd6
Autor:
Zhaoyuan Hou, Chenghong Peng, Frank J. Rauscher, Y. Eugene Chin, Aiwu Zhou, Xiaxing Deng, Baiyong Shen, Hao Chen, Yi Zhu, Jiamin Wang, Xiuqun Zou, Hong Xu, Jiangzhi Chen
PDF file - 329K, Supplementary Figure 1: Mutation of Ring domains of Ring1A/B proteins does not change their subcellular localization. Supplementary Figure 2: qRT-PCR analysis of the known PRC1 target genes HOXC5 and HOXB4 and Snail target gene Cycli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::410264d69aed418fb41716614b8bcf7a
https://doi.org/10.1158/0008-5472.22403010
https://doi.org/10.1158/0008-5472.22403010
Ajuba transactivates N‐cadherin expression in colorectal cancer cells through interaction with Twist
Autor:
Ying Xu, Yimin Chu, Zhou Fengli, Zhaoxia Wu, Rong Kuai, Daming Yang, Xiuqun Zou, Ji Li, Haixia Peng
Publikováno v:
Journal of Cellular and Molecular Medicine
Ajuba is a multiple LIM domain‐containing protein and functions as a transcriptional coregulator to modulate many gene expressions in various cellular processes. Here, we describe that the LIM domain of Ajuba interacts with Twist, and the Twist box
Autor:
Huan Song, Jiamin Wang, Dan Zhang, Ying Xu, Yuquan Yang, Mengying Li, Hao Jia, Haixia Peng, Hong Xu, Zhaoyuan Hou, Xiuqun Zou, Yimin Chu, Jie Zhang, Qun Zhang
Publikováno v:
EMBO Rep
Snail is a dedicated transcriptional repressor and acts as a master inducer of EMT and metastasis, yet the underlying signaling cascades triggered by Snail still remain elusive. Here, we report that Snail promotes colorectal cancer (CRC) migration by
Autor:
Zichao Yu, Qun Zhang, Jiamin Wang, Yingjie Wu, Han Yan, Jie Zhang, Hao Jia, Qi Li, Dan Zhang, Mengying Li, Ningning Bai, Xiuqun Zou, Zhaoyuan Hou
Publikováno v:
Molecular and Cellular Endocrinology. 539:111485
Adipogenesis is regulated by a complicated network of transcription factors among which PPARγ and C/EBP family members are the major regulators. During adipogenesis, C/EBPβ is induced early and then transactivates PPARγ and C/EBPα, which cooperat
Autor:
Yijian Zhang, Chuan-Peng Zhang, Haixia Peng, Qian Cong, Hao Jia, Xiaohong Zhang, J Wang, Yimin Chu, Z Li, Y E Chin, Li Song, Zhaoyuan Hou, K Zhu, Bo Wang, Huanbai Xu, Qing Li, Xiuqun Zou
Publikováno v:
Oncogene. 36:2655-2666
The LIM protein AJUBA is a scaffold protein participating in the regulation of cell adhesion, mitosis, DNA damage, cell differentiation, proliferation, migration and gene transcription. However, its roles in tumorigenesis and progression are poorly d
Autor:
Dan Zhang, Xiao-Dong Yang, Qiwei Li, Wenli Qian, Xiuqun Zou, Mengying Li, Zhaoyuan Hou, Wenguo Li, Jie Zhang, Hongxia Zhao, Xinglong Wu, Lingqiang Zhang, Hao Jia, Qi Li
Publikováno v:
Oncogene. 39(44)
Snail is a master inducer of epithelial-mesenchymal transition (EMT) and metastasis, however, Snail protein is labile and is quickly degraded through the predominate ubiquitination-mediated proteasome pathway. Deubiquitinases (DUBs) can counteract th
Autor:
Weibing Dong, Hongyan Fan, Shengxian Li, Xiuqun Zou, Zhaoyuan Hou, Haipeng Sun, Ying Dong, Jiamin Wang, Qi Li, Wei Liu, Yihong Zhang
Publikováno v:
Molecular Endocrinology. 29:1608-1618
The liver X receptors (LXRs) are important regulators of lipid, cholesterol, and glucose homeostasis by transcriptional regulation of many key genes in these processes, and the transcriptional activities of LXRs are finely controlled by cooperating w