Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Xiuqi Bao"'
Autor:
Caixia Zang, Hui Liu, Jingwen Ning, Qiuzhu Chen, Yueqi Jiang, Meiyu Shang, Yang Yang, Jingwei Ma, Yirong Dong, Jinrong Wang, Fangfang Li, Xiuqi Bao, Dan Zhang
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 172, Iss , Pp 116204- (2024)
HACE1 is a member of the HECT domain-containing E3 ligases with 909 amino acid residues, containing N-terminal ankyrin-repeats (ANK) and C-terminal HECT domain. Previously, it was shown that HACE1 is inactive in human tumors and plays a crucial role
Externí odkaz:
https://doaj.org/article/bc0afd4978f6487ab0d05790511664be
Autor:
Qing-Tong Han, Wan-Qi Yang, Caixia Zang, Linchao Zhou, Chong-Jing Zhang, Xiuqi Bao, Jie Cai, Fangfei Li, Qinyan Shi, Xiao-Liang Wang, Jing Qu, Dan Zhang, Shi-Shan Yu
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 8, Iss 1, Pp 1-10 (2023)
Abstract Tutin, an established toxic natural product that causes epilepsy in rodents, is often used as a tool to develop animal model of acute epileptic seizures. However, the molecular target and toxic mechanism of tutin were unclear. In this study,
Externí odkaz:
https://doaj.org/article/efb38a4a96524d398e3a9b3504c63fdc
Autor:
Hui Liu, Caixia Zang, Junmei Shang, Zihong Zhang, Lu Wang, Hanyu Yang, Chanjuan Sheng, Fangyu Yuan, Cheng Ju, Fangyuan Li, Yang Yu, Xinsheng Yao, Xiuqi Bao, Dan Zhang
Publikováno v:
Food & Nutrition Research, Vol 66, Pp 1-15 (2022)
Background: GJ-4 is extracted from Gardenia jasminoides J. Ellis (Fructus Gardenia) with crocin composition and has been demonstrated to improve memory deficits in several dementia models in our previous studies. Objective: This study aimed to evalua
Externí odkaz:
https://doaj.org/article/d0d23da8ed084344a01f72f70e64907f
Autor:
Cheng Ju, Fangyu Yuan, Lu Wang, Caixia Zang, Jingwen Ning, Meiyu Shang, Jingwei Ma, Gen Li, Yang Yang, Qiuzhu Chen, Yueqi Jiang, Fangfang Li, Xiuqi Bao, Dan Zhang
Publikováno v:
Neurobiology of Disease, Vol 177, Iss , Pp 105988- (2023)
CXC chemokine receptor 2 (CXCR2) plays an important role in demyelinating diseases, but the detailed mechanisms were not yet clarified. In the present study, we mainly investigated the critical function and the potential molecular mechanisms of CXCR2
Externí odkaz:
https://doaj.org/article/455bfa5369e747b894c8870f3c0b3ba8
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 11, Iss 5, Pp 1213-1226 (2021)
The gut microbiota plays an important role in regulating the pharmacokinetics and pharmacodynamics of many drugs. FLZ, a novel squamosamide derivative, has been shown to have neuroprotective effects on experimental Parkinson's disease (PD) models. FL
Externí odkaz:
https://doaj.org/article/09da8f9d6d9f4f24b41535324080feaf
Autor:
Qian Wei, Jian Bai, Daojiang Yan, Xiuqi Bao, Wenting Li, Bingyu Liu, Dan Zhang, Xiangbing Qi, Dequan Yu, Youcai Hu
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 11, Iss 2, Pp 572-587 (2021)
Endophytic fungi are promising producers of bioactive small molecules. Bioinformatic analysis of the genome of an endophytic fungus Penicillium dangeardii revealed 43 biosynthetic gene clusters, exhibited its strong ability to produce numbers of seco
Externí odkaz:
https://doaj.org/article/2c3a43fcb7034fea8a92f6c76f8037bd
Autor:
Hanyu Yang, Lu Wang, Caixia Zang, Xu Yang, Xiuqi Bao, Junmei Shang, Zihong Zhang, Hui Liu, Cheng Ju, Fangyuan Li, Fangyu Yuan, Dan Zhang
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Mitochondrial dysfunction is involved in the pathogenesis of Parkinson’s disease (PD). Mitochondrial morphology is dynamic and precisely regulated by mitochondrial fission and fusion machinery. Aberrant mitochondrial fragmentation, which can result
Externí odkaz:
https://doaj.org/article/c0292df3317942d783b168b72ad7da60
Autor:
Zihong Zhang, Hui Liu, Zhe Zhao, Caixia Zang, Cheng Ju, Fangyuan Li, Lu Wang, Hanyu Yang, Xiuqi Bao, Yang Yu, Xinsheng Yao, Dan Zhang
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 128, Iss , Pp 110335- (2020)
Externí odkaz:
https://doaj.org/article/9f92436781b54df1980cbd3fff065633
GJ-4 alleviates Aβ25-35-induced memory dysfunction in mice through protecting the neurovascular unit
Autor:
Zihong Zhang, Hui Liu, Zhe Zhao, Caixia Zang, Cheng Ju, Fangyuan Li, Lu Wang, Hanyu Yang, Xiuqi Bao, Yang Yu, Xinsheng Yao, Dan Zhang
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 127, Iss , Pp 110131- (2020)
Alzheimer's disease (AD) is the most common neurodegenerative disease. AD has become an important social health problem but there are few therapeutic drugs. Many researchers devote to the development of drugs for the treatment of AD. GJ-4 is crocin e
Externí odkaz:
https://doaj.org/article/99fd6b16113f410d840feeadca31e284
Autor:
Lu Wang, Hanyu Yang, Caixia Zang, Yi Dong, Junmei Shang, Jiajing Chen, Yue Wang, Hui Liu, Zihong Zhang, Heng Xu, Xiuqi Bao, Dan Zhang
Publikováno v:
Neurobiology of Disease, Vol 134, Iss , Pp - (2020)
Multiple sclerosis (MS) is a chronic autoimmune demyelinating disease characterized by the autoimmune attack of oligodendrocytes, leading to demyelination and progressive functional deficits. CXC chemokine receptor 2 (CXCR2) is recently reported to o
Externí odkaz:
https://doaj.org/article/ef9adc22e5dd4f2abb8586e64295adeb