Zobrazeno 1 - 10
of 137
pro vyhledávání: '"Xiuping, Yu"'
Autor:
Santhanasabapathy Rajasekaran, Siyuan Cheng, Nithya Gajendran, Sahar Shekoohi, Liudmila Chesnokova, Xiuping Yu, Stephan N. Witt
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract The Parkinson’s disease protein, alpha-synuclein (α-syn/SNCA), is highly expressed in neurons and melanomas. The goal of this study was to reveal the mechanism(s) of α-syn’s involvement in melanoma pathogenesis. To decipher the genes a
Externí odkaz:
https://doaj.org/article/e0b3c8a4780b4b5f8952b79fd5412b48
Unveiling novel double-negative prostate cancer subtypes through single-cell RNA sequencing analysis
Publikováno v:
npj Precision Oncology, Vol 8, Iss 1, Pp 1-10 (2024)
Abstract Recent advancements in single-cell RNA sequencing (scRNAseq) have facilitated the discovery of previously unrecognized subtypes within prostate cancer (PCa), offering new insights into cancer heterogeneity and progression. In this study, we
Externí odkaz:
https://doaj.org/article/93af65cbcce64ac1a1e9f0bb040c8afc
Autor:
Lin Li, Siyuan Cheng, Yunshin Yeh, Yingli Shi, Nikayla Henderson, David Price, Xin Gu, Xiuping Yu
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
BackgroundNeuroendocrine prostate cancer (NEPCa) is the most aggressive type of prostate cancer (PCa). However, energy metabolism, one of the hallmarks of cancer, in NEPCa has not been well studied. Pyruvate kinase M (PKM), which catalyzes the final
Externí odkaz:
https://doaj.org/article/ba1a2f366d1546e3919fc2496c548a8c
Autor:
Evan Kidder, Meleah Pea, Siyuan Cheng, Satya-Priya Koppada, Suren Visvanathan, Quartina Henderson, Moe Thuzar, Xiuping Yu, Mabruka Alfaidi
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 10 (2023)
IntroductionAtherosclerosis is a progressive disease that develops in areas of disturbed flow (d-flow). Progressive atherosclerosis is characterized by bulky plaques rich in mesenchymal cells and high-grade inflammation that can rupture leading to su
Externí odkaz:
https://doaj.org/article/33e35635e7f04bfaa0ba133242effb8a
Publikováno v:
Biomedicines, Vol 11, Iss 11, p 2987 (2023)
Cellular organisms possess intricate DNA damage repair and tolerance pathways to manage various DNA lesions arising from endogenous or exogenous sources. The dysregulation of these pathways is associated with cancer development and progression. Synth
Externí odkaz:
https://doaj.org/article/b0fe4599ff5f46a29fffb47220391ad0
Autor:
Sahar Shekoohi, Santhanasabapathy Rajasekaran, Dhaval Patel, Shu Yang, Wang Liu, Shile Huang, Xiuping Yu, Stephan N. Witt
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Abstract The protein alpha-synuclein (α-syn) is unusual because, depending on its conformation and the type of cell in which it is expressed, it is pro-death or pro-survival, triggering neurodegeneration in Parkinson’s disease and enhancing cell s
Externí odkaz:
https://doaj.org/article/97f081a407604a379445ec7aeb245044
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract HOX gene-encoded homeobox proteins control body patterning during embryonic development; the specific expression pattern of HOX genes may correspond to tissue identity. In this study, using RNAseq data of 1019 human cancer cell lines that or
Externí odkaz:
https://doaj.org/article/36a528856c4a429f962a893e44363394
Publikováno v:
Frontiers in Molecular Biosciences, Vol 8 (2022)
Externí odkaz:
https://doaj.org/article/03ab0adf2a1d4ef3ba744e0c18b7df0c
Autor:
Hosne Ara, Utsab Subedi, Papori Sharma, Susmita Bhattarai, Sudha Sharma, Shrivats Manikandan, Xiuping Yu, Md. Shenuarin Bhuiyan, Hong Sun, Sumitra Miriyala, Manikandan Panchatcharam
Publikováno v:
Biomolecules, Vol 12, Iss 12, p 1805 (2022)
Lysophosphatidic acid (LPA), a multifunctional endogenous phospholipid, plays a vital role in cellular homeostasis and the malignant behavior of cancer cells through G-protein-coupled receptors. However, the role of LPA in β-catenin-mediated gastric
Externí odkaz:
https://doaj.org/article/f1640294c03644e688e55b75ddfbf7c9
Publikováno v:
Journal of Marine Science and Engineering, Vol 9, Iss 11, p 1204 (2021)
This study focuses on the problem of finite-time tracking control for underactuated surface vessels (USVs) through sliding-mode control algorithms with external disturbances. Considering the nonexistence of relative degree caused by the underactuated
Externí odkaz:
https://doaj.org/article/9d06b904f220412c862d772a21c6c1eb